Tullavis 100 mg/ml Solution for Injection for Cattle, Pigs and Sheep
Active ingredient: Tulathromycin
Form
Injection
Species
Manufacturer
Industrial Veterinaria SA
VMD MA No.
36547/5003
What it's used for
Treatment of infectious bovine keratoconjunctivitis (IBK) associated with susceptible to tulathromycin. Pigs Treatment and metaphylaxis of swine respirator...
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Tullavis 100 mg/ml Solution for Injection for Cattle, Pigs and Sheep — SPC Details
Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.
susceptible to tulathromycin.
Pigs
Treatment and metaphylaxis of swine respiratory disease (SRD) associated with
Actinobacillus pleuropneumoniae, Pasteurella multocida, Mycoplasma hyopneumoniae,
Haemophilus parasuis
presence of the disease in the group must be established before the product is used.
AN: 02317/2025Page 2 of 8
The
disease within 2–3 days.
Sheep
Treatment of the early stages of infectious pododermatitis (foot rot) associated with
virulent Dichelobacter nodosus
Cattle
A single subcutaneous injection of 2.5 mg tulathromycin/kg bodyweight (equivalent to 1
ml/40 kg bodyweight). For treatment of cattle over 300 kg bodyweight, divide the dose
so that no more than 7.5 ml are injected at one site.
Pigs
A single intramuscular injection of 2.5 mg tulathromycin/kg bodyweight (equivalent to 1
ml/40 kg bodyweight) in the neck.
For treatment of pigs over 80 kg bodyweight, divide the dose so that no more than 2 ml
are injected at one site.
For any respiratory disease, it is recommended to treat animals in the early stages of the
disease and to evaluate the response to treatment within 48 hours after injection. If
clinical signs of respiratory disease persist or increase, or if relapse occurs, treatment
should be changed, using another antibiotic, and continued until clinical signs have
resolved.
Sheep
A single intramuscular injection of 2.5 mg tulathromycin/kg body weight (equivalent to 1
ml/40 kg body weight) in the neck.
To ensure correct dosage bodyweight should be determined as accurately as possible.
The cap may be safely punctured up to 100 times.
needle or multi-dose syringe is recommended to avoid excessive broaching of the
stopper.
to any of the excipients.
Very common
(>1 animal / 10 animals
treated):
Injection site swelling
, Injection site fibrosis
,
Injection site haemorrhage
, Injection site
oedema
, Injection site reaction
1,2
, Injection site
pain
1
Can persist for approximately 30 days after injection.
Reversible changes of congestion.
Transient.
Pigs:
Very common
(>1 animal / 10 animals
treated):
Injection site reaction
1,2
, Injection site fibrosis
,
Injection site haemorrhage
, Injection site oedema
1
Can persist for approximately 30 days after injection.
Reversible changes of congestion.
Sheep:
Very common
(>1 animal / 10 animals
treated):
Discomfort
1
Transient, resolving within a few minutes: head shaking, rubbing injection site,
backing away.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or its local representative or the national
competent authority via the national reporting system. See the package leaflet for
respective contact details.
antimicrobials with a similar mode of action such as other macrolides or lincosamides.
Sheep:
The efficacy of antimicrobial treatment of foot rot might be reduced by other factors, such
as wet environmental conditions, as well as inappropriate farm management. Treatment
of foot rot should therefore be undertaken along with other flock management tools, for
example providing dry environment.
Antibiotic treatment of benign foot rot is not considered appropriate. Tulathromycin
showed limited efficacy in sheep with severe clinical signs or chronic foot rot and should
therefore only be given at an early stage of foot rot.
Special precautions for safe use in the target species:
Use of the veterinary medicinal product should be based on susceptibility testing of the
bacteria isolated from the animal. If this is not possible, therapy should be based on local
(regional, farm level) epidemiological information about susceptibility of the target
bacteria. Official, national and regional antimicrobial policies should be taken into account
when the veterinary medicinal product is used.
Use of the
may increase the prevalence of bacteria resistant to tulathromycin and may decrease
the effectiveness of treatment with other macrolides, lincosamides and group B
streptogramins, due to the potential for cross resistance.
If a hypersensitivity reaction occurs appropriate treatment should be administered
without delay.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals:
Tulathromycin is irritating to eyes. In case of accidental eye exposure, flush the eyes
immediately with clean water.
Tulathromycin may cause sensitisation by skin contact. In case of accidental spillage
onto skin, wash the skin immediately with soap and water.
AN: 02317/2025Page 3 of 8
Wash hands after use.
In case of accidental self-injection, seek medical advice immediately and show the
package leaflet or the label to the physician.
Special precautions for the protection of the environment:
Not applicable.
Pigs (meat and offal): 13 days.
Sheep (meat and offal): 16 days.
Not authorised for use in animals producing milk for human consumption.
Do not use in pregnant animals, which are intended to produce milk for human
consumption, within 2 months of expected parturition.
This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.
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