POM-V Prescription Required

Tulaxa 100 mg/ml Solution for Injection for Cattle, Pigs and Sheep

Active ingredient: Tulathromycin

Form

Injection

Species

Cattle Pigs Sheep

Manufacturer

KRKA, d.d., Novo mesto

VMD MA No.

01656/5073

What it's used for

Cattle Treatment and metaphylaxis of bovine respiratory disease (BRD) associated with Mannheimia haemolytica, Pasteurella multocida, Histophilus somni and...

Full indications, dosage and side effects ↓

View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Tulathromycin

1

Ask your vet for a written prescription

They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

Fill it at a registered online retailer

The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Your prescription rights → VMD register of retailers →

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Tulaxa 100 mg/ml Solution for Injection for Cattle, Pigs and Sheep — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 26 Mar 2026.

Cattle
Treatment and metaphylaxis of bovine respiratory disease (BRD) associated with
Mannheimia haemolytica, Pasteurella multocida, Histophilus somni and
bovis
established before the product is used.
Treatment of infectious bovine keratoconjunctivitis (IBK) associated with
bovis
Pigs
Treatment and metaphylaxis of swine respiratory disease (SRD) associated with
Actinobacillus pleuropneumoniae, Pasteurella multocida, Mycoplasma
hyopneumoniae, and susceptible to
tulathromycin. The presence of the disease in the group must be established before
the product is used. The veterinary medicinal product should only be used if pigs are
expected to develop the disease within 2–3 days.

Revised: May 2024
AN: 01453/2023
Sheep
Treatment of the early stages of infectious pododermatitis (foot rot) associated with
virulent Dichelobacter nodosus requiring systemic treatment.

Cattle
Subcutaneous use.
A single subcutaneous injection of 2.5 mg tulathromycin/kg bodyweight (equivalent to
1 ml/40 kg bodyweight). For treatment of cattle over 300 kg bodyweight, divide the
dose so that no more than 7.5 ml are injected at one site.
Pigs
Intramuscular use.
A single intramuscular injection of 2.5 mg tulathromycin/kg bodyweight (equivalent to
1 ml/40 kg bodyweight) in the neck.
For treatment of pigs over 80 kg bodyweight, divide the dose so that no more than 2
ml are injected at one site.
For any respiratory disease, it is recommended to treat animals in the early stages of
the disease and to evaluate the response to treatment within 48 hours after injection.
If clinical signs of respiratory disease persist or increase, or if relapse occurs,
treatment should be changed, using another antibiotic, and continued until clinical
signs have resolved.
Sheep
Intramuscular use.
A single intramuscular injection of 2.5 mg tulathromycin/kg body weight (equivalent to
1 ml/40 kg body weight) in the neck.
To ensure a correct dosage, body weight should be determined as accurately as
possible. The cap may be safely punctured up to 20 times. When treating groups of
animals in one run, use a draw-off needle that has been placed in the vial stopper to
avoid excess broaching of the stopper. The draw-off needle should be removed after
treatment.

Do not use in cases of hypersensitivity to macrolide antibiotics or to any of the
excipients.

Cattle:
Very common
(>1 animal / 10 animals
treated):
Injection site reactions (congestion, oedema,
fibrosis, haemorrhage, pain, swelling)
1
Reversible. May be observed or persist for approximately 30 days after injection.
Pigs:
Very common
(>1 animal / 10 animals
treated):
Injection site reactions (congestion, oedema,
fibrosis, haemorrhage)
1
Reversible, may be observed approximately for 30 days after injection.
Sheep:
Very common
(>1 animal / 10 animals
treated):
Discomfort (head shaking, rubbing injection site,
backing away)
1
The signs resolve within a few minutes.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or the national competent authority via the
national reporting system. See also section 16 of the package leaflet for contact
details.

Cross resistance occurs with other macrolides. Do not administer simultaneously with
antimicrobials with a similar mode of action such as other macrolides or
lincosamides.
Sheep:
The efficacy of antimicrobial treatment of foot rot might be reduced by others factors,
such as wet environmental conditions, as well as inappropriate farm management.
Treatment of foot rot should therefore be undertaken along with other flock
management tools, for example providing dry environment.
Antibiotic treatment of benign foot rot is not considered appropriate. Tulathromycin
showed limited efficacy in sheep with severe clinical signs or chronic foot rot, and
should therefore only be given at an early stage of foot rot.

Special precautions for use in animals
Use of the product should be based on susceptibility testing of the bacteria isolated
from the animal.
If this is not possible, therapy should be based on local (regional, farm level)
epidemiological information about susceptibility of the target bacteria.
Official, national and regional antimicrobial policies should be taken into account
when the product is used.
Use of the product deviating from the instructions given in the SPC may increase the
prevalence of bacteria resistant to tulathromycin and may decrease the effectiveness
of treatment with other macrolides, lincosamides and group B streptogramins, due to
the potential for cross resistance.
If a hypersensitivity reaction occurs appropriate treatment should be administered
without delay.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals
Tulathromycin is irritating to eyes. In case of accidental eye exposure, flush the eyes
immediately with clean water.
Tulathromycin may cause sensitisation by skin contact. In case of accidental spillage
onto skin, wash the skin immediately with soap and water.

Revised: May 2024
AN: 01453/2023
Wash hands after use.
In case of accidental self-injection, seek medical advice immediately and show the
package leaflet or the label to the physician.
Special precautions for the protection of the environment:
Not applicable.
Other precautions:
Not applicable.

None known.

Store in the original container.
Once opened, store below 25C.

Revised: May 2024
AN: 01453/2023

Cattle (meat and offal): 22 days.
Pigs (meat and offal): 13 days.
Sheep (meat and offal): 16 days.
Not authorised for use in animals producing milk for human consumption.
Do not use in pregnant animals, which are intended to produce milk for human
consumption, within 2 months of expected parturition.
5.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.