POM-V Prescription Required Companion Animal

Trymox LA 150 mg/ml Suspension for Injection for Cattle, Sheep, Pigs, Dogs and Cats

Active ingredient: Amoxicillin

Form

Injection

Species

Cats Cattle Dogs Pigs Sheep

Manufacturer

Univet Limited

VMD MA No.

05150/3003

What it's used for

For the treatment of infections caused by bacteria susceptible to amoxicillin and clavulanic acid including: skin disease (including deep and superficial p...

Full indications, dosage and side effects ↓

View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Amoxicillin

1

Ask your vet for a written prescription

They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

Fill it at a registered online retailer

The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Your prescription rights → VMD register of retailers →

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Trymox LA 150 mg/ml Suspension for Injection for Cattle, Sheep, Pigs, Dogs and Cats — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

For the treatment of infections caused by bacteria susceptible to amoxicillin and
clavulanic acid including: skin disease (including deep and superficial pyodermas);
soft tissue infections (abscesses and anal sacculitis); dental infections (e.g.
gingivitis); urinary tract infections; respiratory disease (involving upper and lower
respiratory tract); enteritis.

Dogs and cats - subcutaneous or intramuscular use.
Shake the vial vigorously to achieve full resuspension before use.
This veterinary medicinal product does not contain an antimicrobial preservative.
Swab the septum before removing each dose.
To ensure the correct dosage, bodyweight should be determined as accurately as
possible.
The recommended dosage rate is 15 mg per kg bodyweight, equivalent to 1 ml per
10 kg bodyweight to be repeated once after 48 hours.
AN: 01672/2023Page 4 of 7
AnimalWeight (kg)Dosage volume (ml)Cattle450 kg45.0 mlSheep65 kg6.5 mlPigs150 kg15.0 mlDogs20 kg2.0 mlCats 5 kg0.5 ml
Dose volume is equivalent to 1 ml per 10 kg body weight. If dose volume exceeds 15
ml in cattle and 4 ml in sheep and pigs, it should be divided and injected into two or
more sites.
The stopper should not be punctured more than 40 times.

Do not administer via the intravenous or intrathecal routes.
Do not administer to rabbits, hamsters, gerbils or guinea pigs.
Do not use in cases of hypersensitivity to the active substance or to any of the
excipients.

Cattle, sheep, pigs, dogs, cats:
Rare
(1 to 10 animals / 10,000 animals
treated):
Injection site irritation
Very rare
(<1 animal/ 10,000 animals treated, including
isolated reports):
Allergic reaction (e.g. anaphylactic shock and
urticaria)
2,3
Typically of low intensity and recedes spontaneously and quickly. Frequency may be
decreased by reducing the volume of injection per injection site.
treatment should be discontinued and symptomatic treatment should be initiated.
varying in severity.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or its local representative or the national
competent authority via the national reporting system.
See the package leaflet for respective contact details.

The veterinary medicinal product is not effective against beta-lactamase producing
organisms.
Complete cross-resistance has been shown between amoxicillin and other penicillins,
in particular amino-penicillins.
AN: 01672/2023Page 2 of 7
Use of the veterinary medicinal product/amoxicillin should be carefully considered
when antimicrobial susceptibility testing has shown resistance to penicillins because
its effectiveness may be reduced.

Special precautions for safe use in the target species:
Use of the veterinary medicinal product should be based on susceptibility testing of
the bacteria isolated from the animal. If this is not possible, therapy should be based
on local (regional, farm level) epidemiological information about susceptibility of the
target bacteria.
Official, national and regional antimicrobial policies should be taken into account
when the veterinary medicinal product is used.
Use of the veterinary medicinal product deviating from the instructions given in the
SPC may increase the prevalence of bacteria resistant to amoxicillin and may
decrease the effectiveness of treatment with other penicillins, due to the potential for
cross-resistance.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals:
Care should be taken to avoid accidental self-injection. In case of accidental self-
injection, seek medical advice immediately and show the package leaflet or the label
to the physician.
Penicillins and cephalosporins may cause hypersensitivity (allergy) following
injection, inhalation, ingestion or skin contact. Hypersensitivity to penicillins may lead
to cross-reactions to cephalosporins and vice versa. Allergic reactions to these
substances may occasionally be serious.
1. People with known hypersensitivity to penicillin and cephalosporins should
avoid contact with the veterinary medicinal product.
2. Handle this veterinary medicinal product with great care to avoid exposure,
taking all recommended precautions.
3. If you develop symptoms following exposure such as skin rash, seek medical
advice and show the package leaflet or the label to the physician. Swelling of the
face, lips or eyes or difficulty with breathing, are more serious symptoms and require
urgent medical attention.
Wash hands after use.
Special precautions for the protection of the environment:
Not applicable.
AN: 01672/2023Page 3 of 7

It is not generally recommended to use bactericidal and bacteriostatic antibiotics at
the same time.
Beta-lactam antibiotics are known to interact with antibiotics with bacteriostatic action
such as chloramphenicol, macrolides, sulfonamides and tetracyclines. There is also
synergic action of penicillins with aminoglycosides.

Do not store above 25ºC.
Protect from light.

Dose volume is equivalent to 1 ml per 10 kg body weight. If dose volume exceeds 15
ml in cattle and 4 ml in sheep and pigs, it should be divided and injected into two or
more sites.
The stopper should not be punctured more than 40 times.
3.10 Symptoms of overdose (and where applicable, emergency procedures and
antidotes)
The safety of amoxicillin is typical of that of other penicillins in that intrinsic toxicity is
very low. Amoxicillin has a wide safety margin.
In case of overdose, treatment is symptomatic.
3.11 Special restrictions for use and special conditions for use, including
restrictions on the use of antimicrobial and antiparasitic veterinary
medicinal products in order to limit the risk of development of resistance
Not applicable.
3.12 Withdrawal periods
Cattle:
Meat and offal: 39 days.
Milk: 108 hours (4.5 days).
Pigs:
Meat and offal: 42 days.
Sheep:
Meat and offal: 29 days.
Milk: Not authorised for use in sheep producing milk for human consumption.
4.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.