POM-V Prescription Required

Troxxan 100 mg/ml Solution for Injection for Cattle, Pigs and Sheep

Active ingredient: Tulathromycin

Form

Injection

Species

Cattle Pigs Sheep

Manufacturer

Laboratorios SYVA S.A.

VMD MA No.

31592/4008

What it's used for

Cattle Treatment and metaphylaxis of bovine respiratory disease (BRD) associated with Mannheimia haemolytica, Pasteurella multocida, Histophilus somni and...

Full indications, dosage and side effects ↓

View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Tulathromycin

1

Ask your vet for a written prescription

They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

Fill it at a registered online retailer

The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Your prescription rights → VMD register of retailers →

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Troxxan 100 mg/ml Solution for Injection for Cattle, Pigs and Sheep — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 26 Mar 2026.

Cattle
Treatment and metaphylaxis of bovine respiratory disease (BRD) associated with
Mannheimia haemolytica, Pasteurella multocida, Histophilus somni and
bovis
established before the veterinary medicinal product is used.
Treatment of infectious bovine keratoconjunctivitis (IBK) associated with
bovis
Pigs
Treatment and metaphylaxis of swine respiratory disease (SRD) associated with
Actinobacillus pleuropneumoniae, Pasteurella multocida, Mycoplasma
hyopneumoniae, Haemophilus parasuis and susceptible to
tulathromycin. The presence of the disease in the group must be established before
the veterinary medicinal product is used. The veterinary medicinal product should
only be used if pigs are expected to develop the disease within 2–3 days.

Issued: May 2021
AN: 02134/2019
Sheep
Treatment of the early stages of infectious pododermatitis (foot rot) associated with
virulent Dichelobacter nodosus requiring systemic treatment.

Cattle
Subcutaneous use.
A single subcutaneous injection of 2.5 mg tulathromycin/kg bodyweight (equivalent to
1 ml/40 kg bodyweight). For treatment of cattle over 300 kg bodyweight, divide the
dose so that no more than 7.5 ml are injected at one site.

Issued: May 2021
AN: 02134/2019
Pigs
Intramuscular use.
A single intramuscular injection of 2.5 mg tulathromycin/kg bodyweight (equivalent to
1 ml/40 kg bodyweight) in the neck.
For treatment of pigs over 80 kg bodyweight, divide the dose so that no more than
2 ml are injected at one site.
For any respiratory disease, it is recommended to treat animals in the early stages of
the disease and to evaluate the response to treatment within 48 hours after injection.
If clinical signs of respiratory disease persist or increase, or if relapse occurs,
treatment should be changed, using another antibiotic, and continued until clinical
signs have resolved.
Sheep
Intramuscular use.
A single intramuscular injection of 2.5 mg tulathromycin/kg body weight (equivalent to
1 ml/40 kg body weight) in the neck.
To ensure correct dosage bodyweight should be determined as accurately as
possible to avoid underdosing. For multiple vial entry, an aspirating needle or multi-
dose syringe is recommended to avoid excessive broaching of the stopper.
The cap may be safely punctured up to 25 times in 100 ml-vials and 50 times in 250
ml-vials.

Do not use in cases of hypersensitivity to macrolide antibiotics or to any of the
excipients.

Subcutaneous administration of the veterinary medicinal product to cattle causes
very commonly transient pain reactions and local swellings at the injection site that
can persist for up to 30 days. No such reactions have been observed in pigs and
sheep after intramuscular administration.
Pathomorphological injection site reactions (including reversible changes of
congestion, oedema, fibrosis and haemorrhage) are very common for approximately
30 days after injection in cattle and pig.
In sheep transient signs of discomfort (head shaking, rubbing injection site, backing
away) are very common after intramuscular injection. These signs resolve within a
few minutes.
The frequency of adverse reactions is defined using the following convention:
- very common (more than 1 in 10 animals treated displaying adverse reaction(s))
- common (more than 1 but less than 10 animals in 100 animals treated)
- uncommon (more than 1 but less than 10 animals in 1,000 animals treated)
- rare (more than 1 but less than 10 animals in 10,000 animals treated)
- very rare (less than 1 animal in 10,000 animals treated, including isolated reports).

Cross resistance occurs with other macrolides. Do not administer simultaneously with
antimicrobials with a similar mode of action such as other macrolides or
lincosamides.
Sheep:
The efficacy of antimicrobial treatment of foot rot might be reduced by other factors,
such as wet environmental conditions, as well as inappropriate farm management.
Treatment of foot rot should therefore be undertaken along with other flock
management tools, for example providing dry environment.
Antibiotic treatment of benign foot rot is not considered appropriate. Tulathromycin
showed limited efficacy in sheep with severe clinical signs or chronic foot rot and
should therefore only be given at an early stage of foot rot.

Special precautions for use in animals
Use of the veterinary medicinal product should be based on susceptibility testing of
the bacteria isolated from the animal. If this is not possible, therapy should be based
on local (regional, farm level) epidemiological information about susceptibility of the
target bacteria.
Official, national and regional antimicrobial policies should be taken into account
when the veterinary medicinal product is used. Use of the veterinary medicinal
product deviating from the instructions given in the SPC may increase the prevalence
of bacteria resistant to tulathromycin and may decrease the effectiveness of
treatment with other macrolides, lincosamides and group B streptogramins, due to
the potential for cross resistance.
If a hypersensitivity reaction occurs appropriate treatment should be administered
without delay.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals
Tulathromycin is irritating to eyes. In case of accidental eye exposure, flush the eyes
immediately with clean water.

Issued: May 2021
AN: 02134/2019
Tulathromycin may cause sensitisation by skin contact. In case of accidental spillage
onto skin, wash the skin immediately with soap and water.
Wash hands after use.
In case of accidental self-injection, seek medical advice immediately and show the
package leaflet or the label to the physician.

None known.

This veterinary medicinal product does not require any special storage conditions.

Cattle (meat and offal): 22 days.
Pigs (meat and offal): 13 days.
Sheep (meat and offal): 16 days.

Issued: May 2021
AN: 02134/2019
Not authorised for use in animals producing milk for human consumption.
Do not use in pregnant animals, which are intended to produce milk for human
consumption, within 2 months of expected parturition.
5.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.