Tribex 50 mg/ml Oral Suspension for Sheep
Active ingredient: Triclabendazole
Form
Liquid
Species
Manufacturer
Chanelle Pharmaceuticals Manufacturing Ltd
VMD MA No.
08749/3146
What it's used for
The product is indicated for the treatment of acute, sub-acute and chronic fasciolosis in sheep caused by early immature, immature and adult stages of live...
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Prescription required
Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.
Tribex 50 mg/ml Oral Suspension for Sheep — SPC Details
Source: VMD Summary of Product Characteristics (SPC). Last updated 26 Mar 2026.
in sheep caused by early immature, immature and adult stages of liverfluke (Fasciola
hepatica) susceptible to triclabendazole.
Amended pages: November 2025
AN: 01686/2025
Estimate bodyweight accurately. Shake container before use.
Recommended dose rate:
administration.
DOSAGE GUIDE:
BodyweightDosageBodyweightDosageUp to 10 kg
15 kg
20 kg
25 kg
30 kg
2 ml
3 ml
4 ml
5 ml
6 ml
40 kg
50 kg
60 kg
70 kg
80 kg
8 ml
10 ml
12 ml
14 ml
16 ml
For animals over 80 kg - give an additional 2 ml for each additional 10 kg
bodyweight.
DOSING PROGRAMME:
Routine treatment (Areas of heavy fluke infection)
As a guide, dose all cattle exposed to fluke infected pastures preventatively at
regular intervals of 10 weeks from March/April through to October/November. In
situations where stock are out-wintered, another dose in January may be required.
All animals grazing the pasture should be treated at these times. All bought in
animals should be dosed before joining the main flock. Veterinary advice should be
sought with regard to specific preventative dosing regimes.
Routine treatment (Areas of moderate fluke infection)
Dose all sheep on fluke infected pastures at intervals of 10 weeks throughout the
fluke season, usually September to January/February. All bought in animals should
be dosed before joining the main flock.
An additional preventative treatment in the spring will assist in reducing the amount
of new infestation on pasture in the following autumn.
Treatment of sub-acute and acute outbreaks
The flock should be treated immediately after diagnosis and veterinary advice should
be sought for subsequent dosing intervals. If a preventative fluke dosing programme
is employed, the occurrence of acute fluke is greatly reduced. Retreatment may not
be carried out within 8 weeks.
of development of resistance and could ultimately result in ineffective therapy:
• Too frequent and repeated use of anthelmintics from the same class, over an
extended period of time.
• Under dosing, which may be due to under estimation of body weight,
misadministration of the product or lack of calibration of the dosing device (if any).
Amended pages: November 2025
AN: 01686/2025
Suspected clinical cases of resistance to anthelmintics should be further investigated
using appropriate tests (e.g. Faecal Egg Count Reduction Test). Where the results
of the test(s) strongly suggest resistance to a particular anthelmintic, an anthelmintic
belonging to another pharmacological class and having a different mode of action
should be used.
Resistance to triclabendazole has been reported in Fasciola hepatica in sheep.
Therefore, the use of this product should be based on local (regional / farm)
epidemiological information about susceptibility of the
recommendations on how to limit further selection for resistance to anthelmintics.
Special precautions for use in animals
Only use for liverfluke strains susceptible to triclabendazole. Care must be taken not
to damage the mouth or pharyngeal region when dosing. Clean drenching
equipment before and after use. Shake container before use. Use unaltered
product from the original container.
Special precautions to be taken by the person administering the veterinary
medicinal product to animals
When using the product do not eat, drink or smoke. Wear gloves. Wash splashes
from eyes and skin immediately. Take off any contaminated clothing immediately.
Wash hands and exposed skin before meals and after work. In cases of
hypersensitivity and contact allergy, direct skin contact and inhalation should be
avoided.
Other precautions
The use of Tribex 5% may have harmful effects on fish and aquatic invertebrates.
Sheep must not have any access to surface water such as streams, ponds or ditches
within 7 days after treatment with Tribex. When spreading manure from treated
animals on arable lands a safety distance of 10 m to adjacent surface waters must
be kept.
Protect from frost.
4.9 Amounts to be administered and administration route
For oral administration only, using properly calibrated dosing equipment.
Amended pages: November 2025
AN: 01686/2025
Estimate bodyweight accurately. Shake container before use.
Recommended dose rate:
administration.
DOSAGE GUIDE:
BodyweightDosageBodyweightDosageUp to 10 kg
15 kg
20 kg
25 kg
30 kg
2 ml
3 ml
4 ml
5 ml
6 ml
40 kg
50 kg
60 kg
70 kg
80 kg
8 ml
10 ml
12 ml
14 ml
16 ml
For animals over 80 kg - give an additional 2 ml for each additional 10 kg
bodyweight.
DOSING PROGRAMME:
Routine treatment (Areas of heavy fluke infection)
As a guide, dose all cattle exposed to fluke infected pastures preventatively at
regular intervals of 10 weeks from March/April through to October/November. In
situations where stock are out-wintered, another dose in January may be required.
All animals grazing the pasture should be treated at these times. All bought in
animals should be dosed before joining the main flock. Veterinary advice should be
sought with regard to specific preventative dosing regimes.
Routine treatment (Areas of moderate fluke infection)
Dose all sheep on fluke infected pastures at intervals of 10 weeks throughout the
fluke season, usually September to January/February. All bought in animals should
be dosed before joining the main flock.
An additional preventative treatment in the spring will assist in reducing the amount
of new infestation on pasture in the following autumn.
Treatment of sub-acute and acute outbreaks
The flock should be treated immediately after diagnosis and veterinary advice should
be sought for subsequent dosing intervals. If a preventative fluke dosing programme
is employed, the occurrence of acute fluke is greatly reduced. Retreatment may not
be carried out within 8 weeks.
4.10 Overdose (symptoms, emergency procedures, antidotes), if necessary
No adverse effects were reported following a dose of 12.5 times the recommended
dose. At higher doses (up to 20-fold), mild transient ataxia and weight loss were
observed in some animals 3-6 days after treatment.
Amended pages: November 2025
AN: 01686/2025
4.11 Withdrawal Period(s)
Meat and offal: 56 days.
Milk: Not authorised for use in ewes producing milk for human consumption
including during the dry period. Do not use within 1 year prior to the first lambing in
ewes intended to produce milk for human consumption.
5.
This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.
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Other Products Containing Triclabendazole
These products share the same active ingredient and may be suitable alternatives. Always consult your vet.
Combinex 50 mg/ml + 37.5 mg/ml Oral Suspension for Sheep
POM-VPSElanco GmbH
Combinex 50 mg/ml + 37.5 mg/ml Oral Suspension for Sheep
POM-VPSElanco GmbH
Combinex Cattle Oral Suspension
POM-VPSElanco Europe Ltd
Cydectin TriclaMox 1 mg/ml + 50 mg/ml Oral Solution for Sheep
POM-VPSZoetis UK Limited
Cydectin TriclaMox 1 mg/ml + 50 mg/ml Oral Solution for Sheep
POM-VPSZoetis Belgium S.A.
Cydectin TriclaMox 5 mg/ml + 200 mg/ml Pour-on Solution for Cattle
POM-VPSZoetis UK Limited
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