POM-V Prescription Required Companion Animal

Tolfedine Tablets 6 mg

Active ingredient: Tolfenamic Acid

Form

Tablet

Species

Cats Dogs

Manufacturer

Vetoquinol UK Limited

VMD MA No.

08007/5063

What it's used for

In cats: in febrile syndrome (abscess, fever of unknown origin).

Full indications, dosage and side effects ↓

View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Tolfenamic Acid

1

Ask your vet for a written prescription

They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

Fill it at a registered online retailer

The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Your prescription rights → VMD register of retailers →

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Tolfedine Tablets 6 mg — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

In cats: in febrile syndrome (abscess, fever of unknown origin).

To ensure a correct dosage, body weight should be determined as accurately as
possible.
4 mg tolfenamic acid/kg once daily, i.e. 1 tablet for 1.5 kg of bodyweight
administered in feed for 3 days according to the following table:
Weight of the animal (kg)Number of tablets1 - 212.5 - 3.523.5 - 4.53
In dogs, subject to clinical response, the administration may be repeated every 7
days, ie 3 days of medication followed by 4 days without medication.

Do not administer to animals suffering from cardiac, hepatic or renal disease, where
there is a possibility of gastro-intestinal ulceration or bleeding, where there is
evidence of a blood dyscrasia.
Do not use in cases of hypersensitivity to the active substance or to any of the
excipients.

Dogs and cats:
Rare
(1 to 10 animals / 10,000 animals treated):
Vomiting
, diarrhoea
Polyuria
1,2
Polydipsia
1,2
In most of the cases, these signs cease spontaneously after the treatment
Temporary
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian,
to either the marketing authorisation holder or the national competent authority via
the national reporting system. See the package leaflet for respective contact details.

NSAIDS can cause inhibition of phagocytosis and hence in the treatment of
inflammatory conditions associated with bacterial infections appropriate concurrent
antimicrobial therapy should be instigated.
In dogs, long term treatment of over 3 months duration should be under regular
veterinary supervision. In particular, dogs with hepatic insufficiency should be closely
monitored.

Special precautions for safe use in the target species:
Use in animals less than 6 weeks of age, or in aged animals, may involve additional
risk. If such a use cannot be avoided, animals may require a reduced dosage and
careful clinical management.
Avoid use in any dehydrated, hypovolaemic or hypotensive animal, as there is a
potential risk of increased renal toxicity.
Concurrent administration of potential nephrotoxic drugs should be avoided.
It is preferable that the product is not administered to animals undergoing general
anaesthesia until fully recovered.
Do not exceed the prescribed dosage or duration of treatment.
Animals suffering from a chronic renal insufficiency and requiring an anti-
inflammatory treatment may be treated with tolfenamic acid without requiring an
adjustment of the dosage. However, the use of this product is contraindicated in
acute cases of renal insufficiency.
In case of undesirable effects (anorexia, vomiting, diarrhoea, presence of blood in
faeces) occurring during the treatment, your veterinarian should be contacted for
advice.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals:
In case of accidental contact with eyes, wash with plenty of water.
Special precautions for the protection of the environment:
Not applicable.

Do not administer NSAIDs concurrently or within 24 hours of each other. Some
NSAIDs may be highly bound to plasma proteins and compete with other highly
bound drugs, which can lead to toxic effects.

Do not store above 25°C.
Store in a dry place.

Not applicable.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.