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POM-V Prescription Required Companion Animal

Therios 750 mg Palatable Tablets for Dogs

Active ingredient: Cefalexin

Form

Tablet

Species

Dogs

Manufacturer

Ceva Sante Animale

VMD MA No.

14966/3070

What it's used for

For the treatment of urinary tract infections in dogs (including nephritis and cystitis) caused by organisms sensitive to cefalexin.

Full indications, dosage and side effects ↓
View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Cefalexin

  1. 1

    Ask your vet for a written prescription

    They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.

  2. 2

    Fill it at a registered online retailer

    The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Therios 750 mg Palatable Tablets for Dogs — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

For the treatment of urinary tract infections in dogs (including nephritis and cystitis)
caused by organisms sensitive to cefalexin.
15 mg cefalexin per kg bodyweight twice daily (equivalent to 30 mg per kg
bodyweight per day) for duration of:
- 14 days in cases of urinary tract infection.
- At least 15 days in cases of superficial infectious dermatitis.
- At least 28 days in cases of deep infectious dermatitis.
In severe or acute conditions the dose may be safely doubled to 30 mg/kg twice
daily.
To allow for accuracy of dosing, tablets can be halved or quartered.
Any increase in the dose or duration of treatment should be according to a
risk/benefit assessment by the prescribing veterinarian.
To ensure a correct dosage bodyweight should be determined as accurately as
possible.
The veterinary medicinal product is well accepted by dogs but may be crushed or
added to a small quantity of food immediately prior to feeding if necessary.
Do not use in cases of hypersensitivity to penicillins, cephalosporins or to any the
excipients.
Do not use in case of severe renal failure.
Do not use in rabbits, guinea pigs, hamsters and gerbils.
Dogs:
Rare
(1 to 10 animals / 10,000
animals treated):
Hypersensitivity reactionUndetermined frequency
(cannot be estimated from the
available data):
Vomiting, Diarrhoea
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or the national competent authority via the
national reporting system. See the package leaflet for respective contact details.
None.

Special precautions for safe use in the target species:
Wherever possible, the use of the veterinary medicinal product should be based on
susceptibility testing and take into account official and local antimicrobial policies.
As with other antibiotics which are excreted mainly by the kidneys, systemic
accumulation may occur when renal function is impaired. In case of known renal
insufficiency the dose should be reduced.
The veterinary medicinal product is not recommended for use in dogs less than 6 kg
bodyweight.
Use of the veterinary medicinal product deviating from the instructions given in the
SPC may increase the prevalence of bacteria resistant to cefalexin and may
decrease the effectiveness of treatment with other beta-lactam antibiotics due to the
potential for cross-resistance.
Safety of the excipient, ammonium glycyrrhizate, has not been established in dogs
less than 1 year old.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals:
Cephalosporins may cause sensitisation (allergy) following injection, inhalation,
ingestion or skin contact. Sensitivity to penicillins may lead to cross sensitivity to
cephalosporin and vice versa. Allergic reactions to these substances may
occasionally be serious.
1. People with known hypersensitivity to cephalosporins should avoid contact with the
veterinary
medicinal product.
2. Handle this veterinary medicinal product with great care to avoid exposure, taking
all recommended precautions. Wash hands after use.
3. If you develop symptoms following exposure such as skin rash you should seek
medical advice and show the doctor this warning. Swellings of the face, lips or eyes
or difficulty breathing are more serious symptoms and require urgent medical
attention.
In case of accidental ingestion, particularly by a child, seek medical advice
immediately and show the package leaflet or the label to the physician.
Special precautions for the protection of the environment:
Not applicable.
In order to ensure efficacy, the veterinary medicinal product should not be used in
combination with bacteriostatic antibiotics.
Concurrent use of first generation cephalosporins with aminoglycoside antibiotics or
some diuretics such as furosemide can enhance nephrotoxicity risks.
Do not store above 25C.
Divided tablets should be stored in the blister pack.
Not applicable.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.

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