Syvazul BTV 3 Suspension for Injection for Sheep and Cattle
Active ingredient: Bluetongue virus
Form
Injection
Species
Manufacturer
Laboratorios SYVA S.A.
VMD MA No.
31592/5006
What it's used for
Onset of immunity: 4 weeks after completion of the primary vaccination scheme. The duration of immunity has not been established. Cattle: For active immuni...
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Paying less for Bluetongue virus
-
1
Ask your vet for a written prescription
They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
-
2
Fill it at a registered online retailer
The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.
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Prescription required
Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.
Syvazul BTV 3 Suspension for Injection for Sheep and Cattle — SPC Details
Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.
The duration of immunity has not been established.
Cattle:
For active immunisation of cattle to reduce viraemia caused by bluetongue virus
serotype 3.
Onset of immunity: 3 weeks after completion of the primary vaccination scheme.
The duration of immunity has not been established.
Subcutaneous use.
Administer subcutaneously to sheep from 3 months of age, according to the following
scheme:
-
Cattle:
Intramuscular use.
Administer intramuscularly to cattle from 2 months of age in naïve animals or from 3
months of age in calves born to immune cattle, according to the following scheme:
-
Revaccination:
Not established.
Very common
(>1 animal / 10 animals treated):
- Injection site reaction*, Injection site
erythema
1,
*,
Injection site oedema
1,
*, Injection site
nodule
2,
*
- Elevated temperature
Rare
(1 to 10 animals / 10,000 animals
treated):
- Injection site abscess*
- Abortion, perinatal mortality, premature
parturition
- Apathy, recumbency, anorexia, lethargy
Very rare
(<1 animal / 10,000 animals
treated,
including isolated reports):
- Milk production decrease
- Paralysis, ataxia, blindness,
incoordination
- Pulmonary congestion, dyspnoea
- Rumen atony, bloated, hypersalivation
- Hypersensitivity reactions
- Death
* Most local reactions disappear or become residual (≤ 1 cm) before 70 days,
although residual nodules can persist after that time.
1. Mild to moderate, from 1 to 6 days after administration.
2. Painless, up to 3.8 cm diameter, after 2 to 6 days and diminishes progressively
over time.
3. Not exceeding 2.3 °C, during the 48 hours following vaccination.
4. Hypersalivation may occur with hypersensitivity reactions.
Cattle
Very common
(>1 animal / 10 animals treated):
- Injection site reaction*, Injection site
erythema
1,
*, Injection site oedema
1,*
,
Injection site nodule
2,
*
- Elevated temperature
Rare
(1 to 10 animals / 10,000 animals
treated):
- Injection site abscess*
-
- Anorexia
Very rare
(<1 animal / 10,000 animals treated,
including isolated reports):
- Abortion, perinatal mortality, premature
parturition
- Apathy, recumbency, lethargy
-
-
incoordination
-
-
-
-
* Most local reactions disappear or become residual (≤ 1 cm) before 30 days,
although residual nodules can persist after that time.
1. Mild to moderate, from 1 to 6 days after administration.
2. Painless, up to 7 cm diameter, after 2 to 6 days and diminishes progressively over
time.
3. Not exceeding 2.3 °C, during the 48 hours following vaccination.
4. Hypersalivation may occur with hypersensitivity reactions.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary
medicinal product. Reports should be sent, preferably via a veterinarian, to either the
marketing authorisation holder or the national competent authority via the national
reporting system. See the package leaflet for respective contact details.
If used in other domestic and wild ruminant species that are considered at risk of
infection, its use in these species should be undertaken with care and it is advisable
to test the vaccine on a small number of animals prior to mass vaccination. The level
of efficacy for other species may differ from that observed in sheep and cattle.
No information is available on the use of the vaccine in sheep and cattle with
maternally-derived antibodies.
Special precautions for safe use in the target species:
Not applicable.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals:
In case of accidental self-injection, seek medical advice immediately and show the
package leaflet or the label to the physician.
People with known hypersensitivity to aluminium hydroxide, thiomersal or saponins
should avoid contact with the veterinary medicinal product.
Special precautions for the protection of the environment:
Not applicable.
any other veterinary medicinal product. A decision to use this vaccine before or after
any other veterinary medicinal product therefore needs to be made on a case-by-
case basis.
Do not freeze.
Protect from light.
Store in the original package.
This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.
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Other Products Containing Bluetongue virus
These products share the same active ingredient and may be suitable alternatives. Always consult your vet.
Bluevac BTV Suspension for Injection for Cattle and Sheep
POM-VCZ Vaccines S.A.U.
Bluevac BTV Suspension for Injection for Cattle and Sheep
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Bluevac-3 Suspension for Injection for Sheep and Cattle
POM-VCZ Veterinaria S.A.
BLUEVAC-3 Suspension for Injection for Sheep and Cattle
POM-VCZ Veterinaria S.A.
BTVPUR Suspension for Injection for Sheep and Cattle
POM-VBoehringer Ingelheim Vetmedica GmbH
BTVPUR Suspension for Injection for Sheep and Cattle
POM-VBoehringer Ingelheim Vetmedica Gmbh
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