POM-V Prescription Required

Synulox Lactating Cow Intramammary Suspension

Active ingredients: Amoxicillin, Clavulanic Acid, Prednisolone

Form

Intramammary

Species

Cattle

Manufacturer

Zoetis Belgium S.A.

VMD MA No.

60021/3038

What it's used for

For the treatment of infections caused by bacteria susceptible to amoxicillin and clavulanic acid including: skin disease (including deep and superficial p...

Full indications, dosage and side effects ↓

View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

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1

Ask your vet for a written prescription

They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

Fill it at a registered online retailer

The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

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Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Synulox Lactating Cow Intramammary Suspension — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

For the treatment of infections caused by bacteria susceptible to amoxicillin and
clavulanic acid including: skin disease (including deep and superficial pyodermas);
soft tissue infections (abscesses and anal sacculitis); dental infections (e.g.
gingivitis); urinary tract infections; respiratory disease (involving upper and lower
respiratory tract); enteritis.

disinfected.
The contents of one syringe should be infused into each affected quarter via the teat
canal, immediately after milking, at 12 hour intervals for three consecutive milkings.
In cases of infections caused by Staphylococcus aureus, a longer course of
antibacterial therapy may be required. Therefore overall treatment length must be at
the veterinarian’s discretion but should be long enough to ensure complete resolution
of intramammary infection.

Do not use in cases of hypersensitivity to the active substance or to any of the
excipients.
Do not use in animals which are known to be hypersensitive to -lactamase
antibiotics.

Cattle (lactating cows)
None known.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product.
Reports should be sent, preferably via a veterinarian, to either the marketing
authorisation holder or its local representative or the national competent authority via
the national reporting system. See package leaflet for respective contact details.

Do not use in cases associated with

Special precautions for safe use in the target species:
Swab teat end with appropriate disinfectant before treatment.
Recommendations for prudent use
The product should be used for treatment of clinical mastitis only.
Use of the product should be based on local (regional, farm level) epidemiological
information about susceptibility of the target bacteria and take into account official
and local antimicrobial policies.
The use of the product should preferably be based on susceptibility tests.
Avoid use of the product in herds where no β-lactamase
strains have been isolated. Veterinarians should strive to use narrow spectrum
antibiotics if possible.
Inappropriate use of the product may increase the prevalence of bacteria resistant to
ß-lactam antibiotics and may decrease the effectiveness of treatment with ß-lactam
antibiotics, due to the potential for cross-resistance.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals:
Penicillins and cephalosporins may cause hypersensitivity (allergy) following
injection, inhalation, ingestion or skin contact. Hypersensitivity to penicillins may lead
to cross reactions to cephalosporins and vice versa. Allergic reactions to these
substances may occasionally be serious.
Do not handle this product if you know you are sensitised, or if you have been
advised not to work with such preparations.
Handle this product with great care to avoid exposure, taking all recommended
precautions.
If you develop symptoms following exposure such as a skin rash, you should seek
medical advice and show the doctor this warning. Swelling of the face, lips or eyes or
difficulty with breathing, are more serious symptoms and require urgent medical
attention.
Wash hands after use.
Special precautions for the protection of the environment:
Not applicable.

None known.

Do not store above 25
°
C.
Store in a dry place.

Meat and offal: 7 days.
Milk: 84 hours.
With cows milked twice daily, milk for human consumption may only be taken from
the 7
th
milking after the last treatment. Where any other milking routine is followed,
milk may be taken for human consumption only after the same period from the last
treatment (e.g. with 3 times a day milking, milk may be taken for human consumption
at the 11
th
milking).
4.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.