POM-V Prescription Required

Synulox Bolus 500 mg Film-Coated Tablets

Active ingredients: Amoxicillin, Clavulanic Acid

Form

Tablet

Species

Cattle

Manufacturer

Zoetis UK Limited

VMD MA No.

42058/5177

What it's used for

For the treatment of enteritis and navel ill in calves.

Full indications, dosage and side effects ↓

View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Amoxicillin + Clavulanic Aci...

1

Ask your vet for a written prescription

They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

Fill it at a registered online retailer

The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

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Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Synulox Bolus 500 mg Film-Coated Tablets — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

For the treatment of enteritis and navel ill in calves.

Orally. 6.25-12.5 mg/kg bodyweight twice daily. For example a 40 kg calf
will require ½ bolus twice daily, but this may be doubled in cases of
severe infection.
Treatment should be continued for up to 12 hours after the clinical signs
have subsided, up to a maximum of 3 days of treatment.

In common with other penicillins, the product should not be administered
orally to rabbits, guinea pigs, hamsters or gerbils.
Do not use in animals with known sensitivity to the active ingredients.

None known.

None.

Revised: January 2025
AN: 02727/2024

i) Special precautions for use in animals
None.
ii) Special precautions to be taken by the person administering the
veterinary medicinal product to animals
Penicillins and cephalosporins may cause hypersensitivity (allergy)
following injection, inhalation, ingestion or skin contact.
Hypersensitivity to penicillins may lead to cross reactions to
cephalosporins and vice versa. Allergic reactions to these
substances may occasionally be serious.
Do not handle this product if you know you are sensitised, or if you
have been advised not to work with such preparations.
Handle this product with great care to avoid exposure, taking all
recommended precautions.
If you develop symptoms following exposure such as skin rash, you
should seek medical advice and show the doctor this warning.
Swelling of the face, lips or eyes or difficulty with breathing, are more
serious symptoms and require urgent medical attention.
Wash hands after use.

interaction
None known.

Do not store above 25
°
C.
Store in a dry place.

Meat: 9 Days.
5.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.