POM-VPS Prescription Required

Spirovac Suspension for Injection

Active ingredient: Leptospira borgpetersenii

Form

Injection

Species

Cattle

Manufacturer

Zoetis Belgium S.A.

VMD MA No.

60021/3062

What it's used for

Onset of immunity: 3 weeks. Duration of immunity: 12 months (demonstrated by challenge with Leptospira borgpetersenii serovar Hardjo type hardjobovis). For...

Full indications, dosage and side effects ↓

View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Leptospira borgpetersenii

1

Ask your vet for a written prescription

They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

Fill it at a registered online retailer

The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

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Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Spirovac Suspension for Injection — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

Onset of immunity: 3 weeks.
Duration of immunity: 12 months (demonstrated by challenge with Leptospira
borgpetersenii serovar Hardjo type hardjobovis).
For active immunisation of cattle from 4 weeks of age persistently infected with
Leptospira borgpetersenii serovar Hardjo type hardjobovis: to reduce urinary shedding of
Leptospira borgpetersenii serovar Hardjo type hardjobovis without clearance of renal
colonisation. The epidemiological significance of the reduced shedding has not been
demonstrated.
Onset of immunity: 4 weeks.
Duration of immunity: unknown.

Administration route:
Subcutaneous injection, preferably in the neck. Shake the container well before
withdrawing the dose.
Vaccination scheme:
Basic vaccination scheme:
2 doses of vaccine separated by a 4 to 6 week interval, from 4 weeks of age.
Revaccination scheme:
A single 2 ml dose on an annual basis.

None.

Cattle:
Very common
(>1 animal / 10 animals
treated):
Injection site swelling
Injection site nodule
1
Diffuse and oedematous, up to 10 cm in diameter which can last for up to 66 days. May
be sensitive to palpation the week following vaccination. The swelling is more marked in
pregnant animals, particularly in their third trimester of pregnancy, and can be up to
22 cm in diameter following second injection.
May persist for several weeks.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or the national competent authority via the
national reporting system. See the package leaflet for respective contact details.

Vaccinate healthy animals only.
The vaccination may not prevent abortion is cows in which placental infection has already
occurred.

Special precautions for safe use in the target species:
Vaccinated cattle may be positive in diagnostic tests for leptospirosis and therefore
unacceptable for export to some countries.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals:
Even though animals may have been vaccinated, the risk of transmission of leptospirosis
from cattle to their handlers, albeit very much reduced, remains. Appropriate precautions
should be maintained at all times and prompt medical advice sought in the event of
clinical signs of possible infection.
Special precautions for the protection of the environment:
Not applicable.
Other precautions:
Not applicable.

No information is available on the safety and efficacy of this vaccine when used with any
other veterinary medicinal product.
A decision to use this vaccine before or after any other veterinary medicinal product
therefore needs to be made on a case by case basis.

Store and transport refrigerated (2°C - 8°C).
Do not freeze.
Protect from light.

Zero days.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.