POM-VPS Prescription Required

Rotacur Emulsion for Injection for Cattle

Active ingredients: Bovine coronavirus, Bovine rotavirus, Escherichia coli

Form

Injection

Species

Cattle

Manufacturer

Forte Healthcare Limited

VMD MA No.

27819/5001

What it's used for

For the active immunisation of pregnant cows and heifers to raise antibodies against E. coli are fed colostrum from vaccinated cows during the first week o...

Full indications, dosage and side effects ↓

View official SPC (PDF)

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Clinical information

Rotacur Emulsion for Injection for Cattle — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 26 Mar 2026.

For the active immunisation of pregnant cows and heifers to raise antibodies against
E. coli
are fed colostrum from vaccinated cows during the first week of life, these antibodies
have been demonstrated to reduce the severity of diarrhoea caused by bovine
rotavirus, bovine coronavirus and enteropathogenic F5 (K99)

Amended pages: January 2026
AN: 01140/2025
reduce the shedding of virus by calves infected with bovine rotavirus or bovine
coronavirus.
Onset of immunity: Passive immunity commences with colostrum feeding and is
dependent on calves receiving sufficient colostrum after birth.

For intramuscular use.
Common aseptic procedures should be used during vaccination.
Only sterile syringes and needles should be used.
Allow the vaccine to reach room temperature before use. Shake well before and
occasionally during use to ensure that the sediment is dissolved prior to administration.
For the 90 ml and 450 ml pack sizes, it is recommended to use automated dosing
equipment to protect the stopper against damage from multiple piercing.
One dose: 3 ml
One dose in the course of each pregnancy, given in the 12 – 3 week period before
calving is expected.
Feeding of colostrum
The protection of calves depends on adequate ingestion of colostrum from vaccinated
cows. Measures should be taken to ensure that calves receive sufficient amounts of
colostrum within the first few days of life. If calves do not get enough antibodies through
the colostrum soon after they are born, they will have failure of passive transfer of
antibodies. It is important that all calves receive as much colostrum as possible from
the first milking within the first six hours after calving. It is recommended that at least 3
litres of colostrum are fed within the first 24 hours and this amount is equivalent to
approximately 10% of the weight of a calf.

To achieve optimum results and to reduce infection pressure on the farm, a whole herd
cow vaccination policy should be adopted.

Amended pages: January 2026
AN: 01140/2025

None.

A slight swelling of 5-7 cm in diameter at the site of injection is common and may in
some cases be accompanied initially by increased local temperature. Typically, such
swelling resolves within 15 days.
Slight, transient increases in temperature (up to 0.8 °C) may be observed within 24
hours of vaccination, resolving within 4 days after vaccination.

Amended pages: January 2026
AN: 01140/2025
The frequency of adverse reactions is defined using the following convention:
- very common (more than 1 in 10 animals treated displaying adverse reaction(s))
- common (more than 1 but less than 10 animals in 100 animals treated)
- uncommon (more than 1 but less than 10 animals in 1,000 animals treated)
- rare (more than 1 but less than 10 animals in 10,000 animals treated)
- very rare (less than 1 animal in 10,000 animals treated, including isolated reports).

Vaccinate healthy animals only.

Special precautions for use in animals
Not applicable.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals
To the user:
This veterinary medicinal product contains mineral oil. Accidental injection/self-
injection may result in severe pain and swelling, particularly if injected into a joint or
finger, and in rare cases could result in the loss of the affected finger if prompt medical
attention is not given.
If you are accidentally injected with this veterinary medicinal product, seek prompt
medical advice even if only a very small amount is injected and take the package leaflet
with you.
If pain persists for more than 12 hours after medical examination, seek medical advice
again.
To the physician:
This veterinary medicinal product contains mineral oil. Even if small amounts have
been injected, accidental injection with this veterinary medicinal product can cause
intense swelling, which may, for example, result in ischemic necrosis and even the loss
of a digit. Expert, PROMPT, surgical attention is required and may necessitate early
incision and irrigation of the injected area, especially where there is involvement of
finger pulp or tendon.

No information is available on the safety and efficacy of this vaccine when used with
any other veterinary medicinal product. A decision to use this vaccine before or after
any other veterinary medicinal product therefore needs to be made on a case by case
basis.

Escherichia coli strain EC/17 (inactivated)
expressing F5 (K99) and F41Adhesin ≥ 44.8 % of inhibition (ELISA F5)***
*VNT – virus neutralisation test (rabbit serology induced by 2/3 dose of vaccine)
**HIT – haemagglutination inhibition test (rabbit serology induced by 2/3 dose of
vaccine)
***ELISA – Enzyme-linked immunosorbent assay (rabbit serology induced by 2/3 dose
of vaccine)
Adjuvant:
Montanide ISA 206 VG 1.6 ml
Excipients:
Formaldehyde max. 1.5 mg
Thiomersal max. 0.36 mg
For the full list of excipients, see section

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.