POM-V Prescription Required

Rispoval RS+PI3 IntraNasal Nasal Spray Lyophilisate and Solvent for Suspension for Cattle

Active ingredients: Bovine parainfluenza virus 3, Bovine respiratory syncytial virus

Form

Injection

Species

Cattle

Manufacturer

Zoetis UK Limited

VMD MA No.

42058/5145

What it's used for

For vaccination with Rispoval RS+PI3 IntraNasal only: For active immunisation of maternally derived antibody positive or negative calves from 9 days of age...

Full indications, dosage and side effects ↓

View official SPC (PDF)

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Paying less for Bovine parainfluenza virus 3...

1

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They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

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Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Rispoval RS+PI3 IntraNasal Nasal Spray Lyophilisate and Solvent for Suspension for Cattle — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

For vaccination with Rispoval RS+PI3 IntraNasal only:
For active immunisation of maternally derived antibody positive or negative calves
from 9 days of age against BRSV and PI3V,
excretion of both viruses.
Onset of immunity: 5 days for BRSV and 10 days for PI3V after a single vaccination.
Duration of immunity: 12 weeks after a single vaccination.The duration of protective
immunity against the PI3V fraction may be reduced in MDA positive calves vaccinated
before 3 weeks of age.
For primary vaccination using Rispoval RS/Pi3 IntraNasal and booster vaccination with
Rispoval 2/BRSV + Pi3*, refer to the Rispoval 2/BRSV Pi3* product information for
specific details on indications.

Revised October 2024
AN: 02386/2023
* Where this veterinary medicinal product is authorised.

None.

Cattle:
Rare
(1 to 10 animals / 10,000 animals
treated):
Hypersensitivity reaction (e.g. anaphylactic-type
reaction)
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or the national competent authority via the
national reporting system. See the package leaflet for respective contact details.

Revised October 2024
AN: 02386/2023

Vaccinate healthy animals only.
Animals should preferably be vaccinated at least 10 days before a period of stress or
high infection risk like re-grouping or transport of animals, or at the start of the autumn
season. To achieve optimal results, it is recommended to vaccinate all the calves
within the same herd.

Special precautions for use in animals
Vaccinal viruses can spread from vaccinated to non-vaccinated calves and may cause
a serological response, but without causing clinical signs. In laboratory experiments
based on the data using 3 week-old animals, shedding was observed for BRSV and
PI3V up to 11 and 7 days respectively after vaccination with one dose containing the
maximal virus content.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals
Not applicable.
Special precautions for the protection of the environment
Not applicable.
Other precautions
Not applicable.

No information is available on the safety and efficacy of this vaccine when used with any
other veterinary medicinal product. A decision to use this vaccine before or after any
other veterinary medicinal product therefore needs to be made on a case by case basis.

Store and transport refrigerated (2 °C – 8 °C).
Do not freeze.
Protect from light.

- 10
8.6
CCID50.
Bovine respiratory syncytial virus (BRSV), strain 375, live 10
5.0
- 10
7.2
CCID50.
CCID50: Cell Culture Infective Dose 50%.
Excipients:
For a full list of excipients, see section

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.