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POM-V Prescription Required Companion Animal

Rilexine 300 mg Tablets for Dogs

Active ingredient: Cefalexin

Form

Tablet

Species

Dogs

Manufacturer

Virbac

VMD MA No.

05653/4133

What it's used for

For the treatment of urinary-tract infections in dogs (including nephritis and cystitis) caused by organisms susceptible to Cefalexin.

Full indications, dosage and side effects ↓
View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Cefalexin

  1. 1

    Ask your vet for a written prescription

    They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.

  2. 2

    Fill it at a registered online retailer

    The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Rilexine 300 mg Tablets for Dogs — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

For the treatment of urinary-tract infections in dogs (including nephritis and cystitis) caused
by organisms susceptible to Cefalexin.
To achieve this dosage, administer:
•

Amended pages: July 2025
To ensure a correct dosage, body weight should be determined as accurately as possible
to avoid underdosing.
Due to its palatable formulation, the product is well accepted by dogs but may be crushed
or added to food if necessary.
In severe or acute conditions, the dose may be safely doubled.
Do not use in cases of hypersensitivity to penicillins and cephalosporins.
Do not use in rabbits, guinea pigs, hamsters and gerbils.

Amended pages: July 2025
Dogs:
Uncommon
(1 to 10 animals / 1,000 animals treated):
LethargyRare
(1 to 10 animals / 10,000 animals treated):
Hypersensitivity reaction
(e.g Allergic
skin reaction, Hives, Allergic oedema,
Abnormal breathing, Circulatory
disorder,)
Very rare
(<1 animal / 10,000 animals treated, including
isolated reports):
Vomiting
,
Diarrhoea
1
In animals sensitive to penicillins/cephalosporins.
lactam may occur.
If vomiting and/or diarrhea occurs repeatedly, treatment should be discontinued and the
advice of the treating veterinarian sought.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or its local representative or the national
competent authority via the national reporting system. See also the package leaflet for
respective contact details.
None.

Special precautions for safe use in the target species
As with other antibiotics which are excreted mainly by the kidneys, unnecessary
accumulation may occur in the body when renal function is impaired. In case of known
renal insufficiency, the dose should be reduced and antimicrobials known to be
nephrotoxic should not be administered concurrently.
This product should not be used to treat puppies of less than 1 kg of bodyweight.
Use of the product deviating from the instructions given in the SPC may increase the
prevalence of bacteria resistant to Cefalexin and may decrease the effectiveness of
treatment with penicillins due to the potential for cross-resistance.
Use of the product should be based on susceptibility testing of the bacteria isolated from
the animal. If this is not possible, therapy should be based on local epidemiological
information.
Official, national and regional antimicrobial policies should be taken into account when the
product is used.
As the tablets are palatable to animals there is a danger of excessive ingestion. The
tablets must therefore be stored out of the reach of animals.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals:
Penicillins and cephalosporins may cause hypersensitivity (allergy) following injection,
inhalation, ingestion or skin contact. Hypersensitivity to penicillin may lead to cross
sensitivity to cephalosporin and . Allergic reactions to these substances may
occasionally be serious.
1- Do not handle this product if you know you are sensitised or if you have been advised
not to work with such preparations.
2- Handle this product with great care to avoid exposure, taking all recommended
precautions. Wash hands after use.
3- If you develop symptoms following exposure such as skin rash, seek medical advice
and show the package leaflet or the label to the physician. Swelling of the face, lips or
eyes or difficulty with breathing are more-serious symptoms and require urgent medical
attention.
Special precautions for the protection of the environment:
Not applicable.

Amended pages: July 2025
The association of first-generation cephalosporins with aminoglycoside antibiotics and
some diuretics such as furosemide can enhance nephrotoxicity risks.
The bactericidal activity of cephalosporins is reduced by concomitant administration of
bacteriostatic acting compounds (tetracyclines, chloramphenicol, macrolides and
rifampicin).
Keep the blisters in the outer carton in order to protect from light.
Divided tablets should be stored in blister packs.
Not applicable.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.

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