Quiflor 20 mg Tablets for Dogs

A low urinary pH could have an inhibitory effect on the activity of marbofloxacin.
Pyoderma occurs mostly secondary to an underlying disease, thus, it is advisable to
determine the underlying cause and to treat the animal accordingly.

Special precautions for safe use in the target species:
High doses of some fluoroquinolones may have epileptogenic potential. Cautious use
is recommended in dogs diagnosed as suffering from epilepsy. However, at the
therapeutic recommended dosage, no severe side-effects are to be expected in
dogs. Fluoroquinolones have been shown to induce erosion of articular cartilage in
juvenile dogs and care should be taken to dose accurately especially in young
animals. At the recommended dose rate, no lesions of the articular joints were
encountered in clinical studies.
Official and local antimicrobial policies should be taken in to account when the
veterinary medicinal product is used. Fluoroquinolones should be reserved for the
treatment of clinical conditions which have responded poorly, or are expected to
respond poorly to other classes of antimicrobials. Whenever possible, use of
fluoroquinolones should be based on susceptibility testing. Use of the product
deviating from the instructions given in the SPC may increase the prevalence of
bacteria resistant to the (fluoro)quinolones and may decrease effectiveness of
treatment with other quinolones due to the potential for cross-resistance.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals:
People with known hypersensitivity to (fluoro)quinolones should avoid contact with
the veterinary medicinal product.
In case of accidental ingestion seek medical advice immediately and show the
package leaflet or the label to the physician.
Wash hands after use.
Special precautions for the protection of the environment:
Not applicable.