Skip to content
POM-V Prescription Required

Poulvac IB Primer

Active ingredient: Infectious bronchitis virus

Form

Liquid

Species

Chickens

Manufacturer

Zoetis Belgium S.A.

VMD MA No.

60021/3070

What it's used for

For active immunisation of chickens against Massachusetts serotype strains and D274 like strains of Avian Infectious Bronchitis virus (IBV). Onset of immun...

Full indications, dosage and side effects ↓
View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Infectious bronchitis virus

  1. 1

    Ask your vet for a written prescription

    They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.

  2. 2

    Fill it at a registered online retailer

    The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Poulvac IB Primer — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

For active immunisation of chickens against Massachusetts serotype strains
and D274 like strains of Avian Infectious Bronchitis virus (IBV).
Onset of immunity: 27 days after vaccination
Duration of immunity: 16 weeks
Vaccination scheme:
Broilers: vaccination from first day of life.
Future layers or breeders: vaccination from first day of life or during the 3rd to
4th week of life for immediate protection of young chickens and priming for
subsequent vaccinations with an inactivated vaccine.
Layer or breeders: vaccination from onset of lay.
One dose of vaccine per bird administered by spray administration, eye drop
administration or drinking water administration. The amount of water to be
used depends on the method of administration:
For spray administration: Dilute and administer the reconstituted vaccine at a
rate of one dose of reconstituted vaccine per bird, according to the directions
of your specific coarse spray vaccination equipment. Recommended volume
for one dose is between 0.1 and 0.5 ml.
The spray device used must be set to a droplet size of 0.12 to 0.15 mm in
diameter. The distance from the spray head to the bird should be
approximately 50 cm.
During spraying and for about 20 - 30 minutes thereafter, ventilation should be
switched off or reduced. Dimming light sources is recommended to avoid
unsettling the animals.
For eye drop administration: 50 ml per 1000 birds.

Amended Pages: July 2025
AN: 04282/2024
One drop (0.05 ml) of the vaccine solution is administered into an eye. In
doing so, the head of the animal must be fixed so that the drop does not run
down. 1000 doses of the vaccine are dissolved in 50 ml water.
For drinking water administration: Depending on the age of the birds: The
amount of water in litres per 1000 chickens should be set according to the age
of the chickens in days (up to a maximum of 40 litres).
Water containing a high level of chlorine or metal ions should not be used and
conduit pipes, tubing, etc. should be thoroughly clean and free of traces of
disinfectants and detergents. It is recommended to add protective proteins in
the form of skimmed milk powder (2 g per litre of water) or skimmed milk (1
litre per 50 litres of water) to the water.
The birds should be deprived from water about 2 hours before vaccination.
For vaccination, use as many litres of water as the age of the birds in days,
per 1000 birds, up to a maximum of 40 litres as indicated above.
Prepare the amount of vaccine to be used within 2 hours. Remove the sealing
cap and stopper from the vaccine vial and suspend the vaccine in the
corresponding amount of water and mix carefully. Care should be taken to
empty the ampoule completely and administer the diluted vaccine
immediately.
Make sure that birds do not have access to untreated water until the treated
water has been consumed.
One day before and after vaccination no drugs or disinfectants should be
applied to the chickens.
None.

Amended Pages: July 2025
AN: 04282/2024
In very rare cases, a slight reaction to vaccination can be observed in the form
of transient, mild respiratory symptoms.
The frequency of adverse reactions is defined using the following convention:
- very common (more than 1 in 10 animals treated displaying adverse
reaction(s))
- common (more than 1 but less than 10 animals in 100 animals treated)
- uncommon (more than 1 but less than 10 animals in 1,000 animals treated)
- rare (more than 1 but less than 10 animals in 10,000 animals treated)
- very rare (less than 1 animal in 10,000 animals treated, including isolated
reports).
Vaccinate healthy animals only.

Special precautions for use in animals
The vaccine strain may spread to unvaccinated chickens. Safety and
reversion to virulence trials have shown that vaccine strain is safe for
chickens. It is recommended to vaccinate all birds on a site at the same time.
Special precautions to be taken by the person administering the veterinary
medicinal product to animals
Personal protective equipment consisting of goggles and dust masks or a
helmet with filtered air circulation should be worn when handling the veterinary
medicinal product especially while vaccination according to the spraying
method.
Personnel involved in attending vaccinated chickens should follow general
hygiene principles (changing clothes, wearing gloves, cleaning and
disinfection of boots).
interaction
Safety and efficacy data are available which demonstrate that this vaccine can
be administered from day of age onwards by course spray and eyedrop
before administration of Poulvac IB QX (where authorised) with a 7 to 14 day
interval between both administrations. For the associated use, the onset of

Amended Pages: July 2025
AN: 04282/2024
immunity is 21 days after the Poulvac IB QX vaccination for the claimed
protection against QX-like IBV strain and the onset of immunity is 27 days
against Massachusetts serotype and D274-like strains of IBV after the
Poulvac IB Primer vaccination. An onset of immunity of 21 days after the
second vaccination against IBV Variant 2 (IS-1494-like) and 793B serotype
strains has also been established for the associated use, with Poulvac IB QX
as detailed above, as demonstrated by a reduction of respiratory signs caused
by Variant 2 (IS-1494-like) and 793B serotype strains of IBV (as assessed by
the ciliary activity of tracheal explants). The possible interference of MDAs on
efficacy against Variant 2 and 793B serotype strains was not investigated.
The safety parameters and adverse reactions are not different from those
described for the vaccines administered separately.
Safety and efficacy data are available which demonstrate that this vaccine,
when administered by the spray route to maternal antibody positive chicks,
can be administered on the same day as Poulvac NDW.
No information is available on the safety and efficacy of this vaccine when
used with any other veterinary medicinal product except the product
mentioned above. A decision to use this vaccine before or after any other
veterinary medicinal product therefore needs to be made on a case by case
basis.
Store and transport refrigerated (2°C – 8°C).
Protect from light.
Do not freeze.
EID50Live, attenuated avian Infectious Bronchitis Virus, strain D274
Clone:
3.0
– 10
5.4
EID50
Excipients:
For the full list of excipients, see section

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.

Medication costs adding up?

Pet insurance can cover prescription medications. Find the right policy for your pet.

Compare insurance

Find cheaper vets near you

Compare vet consultation prices in your area. Save on procedures and get a prescription to buy medications online.