Ovivac P Plus Suspension for Injection for Sheep

Administration: Subcutaneous use.
The vaccine should be administered by subcutaneous injection in the lateral side of
the upper neck observing aseptic precautions.
All lambs not previously vaccinated with the veterinary medicinal product must
receive two injections, each of 2 ml, separated by an interval of 4 - 6 weeks.
Thereafter they must receive booster injections at intervals of not more than 12
months.
On farms where the incidence of pasteurellosis is high, a supplementary booster
vaccination with Ovipast Plus (Pasteurella vaccine) may be required 2 - 3 weeks prior
to expected seasonal outbreaks.
The veterinary medicinal product should not be used in lambs less than 3 weeks of
age due to the possible immunological incompetence of the very young lamb and
competition from any maternally derived colostral antibodies. Lambs born to
Heptavac P Plus vaccinated ewes will, provided they receive sufficient immune
colostrum during the first 1 - 2 days of life, have adequate initial levels of antibody to
aid in the control of lamb dysentery, pulpy kidney, tetanus and pasteurellosis. To
maintain aid in the control of pulpy kidney, tetanus and pasteurellosis, lambs being
retained for late fattening or storing will require a full vaccination course of Ovivac P
Plus. At a minimum age of 3 weeks these lambs should receive two injections, each
of 2 ml, separated by an interval of 4 - 6 weeks.
Lambs being retained for subsequent breeding will require a full course of vaccination
with a suitable breeding stock vaccine. The combined 7 in 1 Clostridial plus
Pasteurella vaccine, Heptavac P Plus, is the recommended breeding stock vaccine
since it provides optimal aid in the control of the predominant clostridial diseases in
adult sheep by active immunisation and in young lambs by passive immunisation.
The vaccine bottle must be shaken well before use.
The vaccine may be administered using a sterile needle and syringe, providing a
fresh sterile needle is used each time the rubber cap is punctured, to avoid
contamination of the remaining contents.
Syringes and needles must be from gamma irradiated packs or freshly sterilised by
boiling for 20 minutes.
It is recommended that an automatic vaccinator is used. Since the bottle containing
this product is non-collapsible the vaccinator must have a vented draw-off spike or
similar device. The instructions supplied with such syringes should be noted and care
should be taken to ensure the delivery of the full dose, particularly with the final few
doses from the bottle.
Partially used containers must be discarded at the end of each day's operations.
This vaccine has been developed following research and development which resulted
in the application of the ‘IRP’ technology for the manufacture of the pasteurella
components of the vaccine. The inclusion of these IRP components should provide
enhanced efficacy and cross protection e.g. protection against serotype A12, which is
not included in the vaccine, has been demonstrated. Studies on the response of
sheep to these vaccines show that two injections separated by an interval of
4-6 weeks are required to gain the full benefit of the ‘IRP’.