Ovipast Plus Suspension for Injection for Sheep
Active ingredients: Mannheimia haemolytica, Pasteurella trehalosi
Form
Injection
Species
Manufacturer
Intervet International B.V.
VMD MA No.
06376/3064
What it's used for
the control of pneumonic pasteurellosis in sheep of all ages from a minimum age of 3 weeks and in the control of systemic pasteurellosis in weaned fattenin...
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Prescription required
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Ovipast Plus Suspension for Injection for Sheep — SPC Details
Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.
3 weeks and in the control of systemic pasteurellosis in weaned fattening and
breeding sheep.
The vaccine may be used in pregnant ewes as an aid in the control of pasteurellosis
in their lambs provided that the lambs receive sufficient immune colostrum during the
first 1-2 days of life.
Onset of immunity: As with most inactivated vaccines, significant levels of immunity
cannot be expected until 2 weeks after the second dose vaccine in the primary
vaccination course.
Duration of immunity: Evidence of efficacy of the Pasteurella/Mannheimia
component was generated in an experimental infection model using Heptavac P
Plus and it is not possible to provide duration of immunity information using this
system. There are reports that active immunity will last for up to 1 year and that
passive immunity will persist for up to 4 weeks after birth in lambs from ewes
vaccinated with conventional Pasteurella vaccines.
interval of 4-6 weeks. Thereafter they must receive booster injections at intervals of
not more than 12 months.
In adult breeding ewes these yearly booster injections should be given during the
pre-lambing period, 4-6 weeks pre-lambing, as an aid in the control of pasteurellosis
in their lambs.
On farms where the incidence of pasteurellosis is high, a supplementary booster
vaccination with this vaccine may be required 2-3 weeks prior to expected seasonal
outbreaks.
The vaccine bottle must be shaken well before use.
Strict precautions should be taken against contamination of the vaccine. The vaccine
must be administered using a sterile needle and syringe, providing a fresh sterile
needle is used each time the rubber cap is punctured, to avoid contamination of the
remaining contents. Syringes and needles must be from gamma-irradiated packs or
freshly sterilised by boiling for a least 20 minutes.
The use of an automatic vaccinator is recommended. Since the bottle is non-
collapsible, a vaccinator with a vented draw-off spike or similar device must be used.
The instructions supplied with such equipment should be noted and care should be
taken to ensure the delivery of the full dose, particularly with the final few doses from
the bottle.
Partially used containers must be discarded at the end of each day's operations, as
re puncture of the rubber cap could cause contamination of the remaining contents.
This vaccine has been developed following research and development which
resulted in the application of new ‘IRP’ technology for the manufacture of the
Pasteurella/Mannheimia components in this vaccine. The inclusion of these IRP
components should provide enhanced efficacy and cross protection e.g. protection
against serotype A12, which is not included in the vaccine, has been demonstrated.
Studies on the response of sheep to this vaccine show that two injections separated
by an interval of 4-6 weeks are required to gain the full benefit of the ‘IRP’.
Common
(1 to 10 animals / 100 animals
treated):
Injection site swelling
, Injection site
warmth
Very rare
(<1 animal / 10 000 animals
treated, including isolated reports):
Hypersensitivity reaction
May be present for up to 3-4 months post-vaccination. They do not appear to
inconvenience the animals or hinder neck movement.
Typically associated with swelling and up to 14 days after vaccination.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian,
to either the marketing authorisation holder or its local representative or the national
competent authority via the national reporting system. See the package leaflet for
respective contact details.
Special precautions for safe use in the target species:
The nutritional and metabolic status of pregnant ewes is extremely important at the
time of vaccination. If in doubt, advice should be sought from a veterinary surgeon.
In any group of animals, a small number of individuals may fail to respond to
vaccination as a result of immunological incompetence. Satisfactory immune
responses will only be attained in healthy animals, thus it is important to avoid
vaccination of animals which have intercurrent infection or metabolic disorder.
Amended Pages: November 2025
MA split from GB MA following AN: 04367/2024
When handling sheep, stress should be avoided, particularly during the later stages
of pregnancy when there is a risk of inducing metabolic disorders which may lead to
abortion.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals:
In case of accidental self-injection, seek medical advice immediately and show the
package leaflet or the label to the physician.
Special precautions for the protection of the environment:
Not applicable.
any other veterinary medicinal product. A decision to use this vaccine before or after
any other veterinary medicinal product therefore needs to be made on a case-by-
case basis.
Amended Pages: November 2025
MA split from GB MA following AN: 04367/2024
Do not freeze.
Protect from light.
This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.
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Other Products Containing Mannheimia haemolytica
These products share the same active ingredient and may be suitable alternatives. Always consult your vet.
Bovalto Respi 3 Suspension for Injection for Cattle
POM-VBoehringer Ingelheim Animal Health UK Ltd
Bovalto Respi 3 Suspension for Injection for Cattle
POM-VBoehringer Ingelheim Vetmedica GmbH
Bovalto Respi 4 Suspension for Injection
POM-VBoehringer Ingelheim Animal Health UK Ltd
Bovalto Respi 4 Suspension for Injection
POM-VBoehringer Ingelheim Vetmedica GmbH
Bovilis Bovipast RSP
POM-VIntervet International B.V.
Bovilis Bovipast RSP
POM-VIntervet International B.V.
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