POM-V Prescription Required

Orbenin Extra Dry Cow 600 mg Intramammary Suspension

Active ingredient: Cloxacillin

Form

Intramammary

Species

Cattle

Manufacturer

Zoetis Belgium S.A.

VMD MA No.

60021/3089

What it's used for

Orbenin Extra Dry Cow is recommended for use in cows at drying off, to treat existing intramammary infections and to provide protection against further inf...

Full indications, dosage and side effects ↓

View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Cloxacillin

1

Ask your vet for a written prescription

They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

Fill it at a registered online retailer

The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Your prescription rights → VMD register of retailers →

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Orbenin Extra Dry Cow 600 mg Intramammary Suspension — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

Orbenin Extra Dry Cow is recommended for use in cows at drying off, to
treat existing intramammary infections and to provide protection against
further infections during the dry period. The concomitant use of Orbeseal
at drying off provides additional protection against the ingress of udder
pathogens, contributing to preventing both subclinical infections and
clinical mastitis during early lactation.

One syringe to be infused per quarter immediately after cleaning and
disinfecting the teats following the last milking before drying off.
Thoroughly clean and disinfect the teat orifice before use. Care should be
taken to avoid contamination of the syringe nozzle. After infusion it is
advisable to dip each teat in an authorised teat dip.

Do not use in the lactating cow.

None.

None.

i) Special precautions for use in animals
None.

Revised: May 2025
AN: 00170/2025
ii) Special precautions to be taken by the person administering the
veterinary medicinal product to animals
Penicillins and cephalosporins may cause hypersensitivity
(allergy) following injection, inhalation, ingestion or skin
contact. Hypersensitivity to penicillins may lead to cross-
reactions to cephalosporins and vice versa. Allergic reaction to
these substances may occasionally be serious.
Do not handle this product if you know you are sensitised, or if
you have been advised not to work with such preparations.
Handle this product with great care to avoid exposure, taking
all recommended precautions.
If you develop symptoms following exposure, such as a skin
rash, you should seek medical advice and show the doctor this
warning. Swelling of the face, lips or eyes or difficulty with
breathing are more serious symptoms and may require urgent
medical attention.
Wash hands after use.

interaction
None known.

Do not store above 25°C.
The syringe may only be used once. Part used syringes must be
discarded.

The following applies to the use of Orbenin Extra Dry Cow either alone or
in combination with Orbeseal. Not intended for use in cows with dry
periods of 42 days or less. Milk for human consumption may only be taken
from 96 hours after calving (that is, at the eighth milking in cows milked
twice daily). If calving occurs before 42 days after last treatment, milk for
human consumption may only be taken from 42 days plus 96 hours after
the last treatment. Cattle must not be slaughtered for human consumption
during treatment. Cattle may be slaughtered for human consumption only
after 28 days from the last treatment.
5.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.