POM-V Prescription Required

Orbenin Dry Cow 500 mg Intramammary Suspension

Active ingredient: Cloxacillin

Form

Intramammary

Species

Cattle

Manufacturer

Zoetis UK Limited

VMD MA No.

42058/5210

What it's used for

For the infusion of cows at drying off, to treat mastitis infections and to provide protection against further infections during the dry period.

Full indications, dosage and side effects ↓

View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Cloxacillin

1

Ask your vet for a written prescription

They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

Fill it at a registered online retailer

The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Your prescription rights → VMD register of retailers →

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Orbenin Dry Cow 500 mg Intramammary Suspension — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 26 Mar 2026.

For the infusion of cows at drying off, to treat mastitis infections and to
provide protection against further infections during the dry period.

One syringe per quarter, immediately after the final milking of lactation. At
drying off, clean and disinfect the teat following the last milking, insert
nozzle into the teat and apply gentle and continuous pressure until the
suspension is expressed.
Each syringe must only be used once. Part used syringes must be
disposed of, see section 6.6 for disposal advice.

Do not use in the lactating cow.

None.

None.

i) Special precautions for use in animals
For single use only.

Revised: May 2025
AN: 00170/2025
ii) Special precautions to be taken by the person administering
the veterinary medicinal product to animals
Penicillins and cephalosporins may cause hypersensitivity
(allergy) following injection, inhalation, ingestion or skin
contact. Hypersensitivity to penicillins may lead to cross
reactions to cephalosporins and vice versa. Allergic reaction to
these substances may occasionally be serious.
Do not handle this product if you know you are sensitised, or if
you have been advised not to work with such preparations.
Handle this product with great care to avoid exposure, taking
all recommended precautions.
If you develop symptoms following exposure, such as a skin
rash, you should seek medical advice and show the doctor this
warning. Swelling of the face, lips or eyes or difficulty with
breathing are more serious symptoms and may required urgent
medical attention.
Wash hands after use.

interaction
None known.

Do not store above 25
°
C.

Not intended for use within 30 days of calving. Milk for human
consumption may only be taken from 204 hours after calving. If calving

Revised: May 2025
AN: 00170/2025
occurs before 30 days after last treatment, milk for human consumption
may only be taken after 30 days plus 204 hours after last treatment.
Animals must not be slaughtered for human consumption during
treatment.
Cattle may be slaughtered only after 28 days from the last treatment.
5.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.