POM-V Prescription Required

Octacillin 697 mg/g Powder for Use in Drinking Water for Pigs

Active ingredient: Amoxicillin

Form

Powder

Species

Pigs

Manufacturer

Eurovet Animal Health B.V.

VMD MA No.

16849/4030

What it's used for

For the treatment of infections caused by bacteria susceptible to amoxicillin and clavulanic acid including: skin disease (including deep and superficial p...

Full indications, dosage and side effects ↓

View official SPC (PDF)

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Paying less for Amoxicillin

1

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2

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Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Octacillin 697 mg/g Powder for Use in Drinking Water for Pigs — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

For the treatment of infections caused by bacteria susceptible to amoxicillin and
clavulanic acid including: skin disease (including deep and superficial pyodermas);
soft tissue infections (abscesses and anal sacculitis); dental infections (e.g.
gingivitis); urinary tract infections; respiratory disease (involving upper and lower
respiratory tract); enteritis.

Pigs:
The recommended daily dose is 16 mg amoxicillin trihydrate - corresponding to 14 mg
amoxicillin per kg of body weight, i.e. 20 mg of the veterinary medicinal product per kg of
body weight equivalent to 1 gram veterinary medicinal product per 50 kg body weight per
day, given for 3-5 consecutive days. In case of severe infections the medication period
must be prolonged to 5 days as determined by the attending veterinary surgeon.
Bolus dosage: It is recommended to administer the veterinary medicinal product once a
day for a limited period of time. Shut off the drinking water system for approx. two hours
(shorter time in warm weather) until the time of medication. Sprinkle the calculated daily
quantity of powder on the surface of 5-10 litres water. Mix thoroughly until the powder has
dissolved. Mix this solution by stirring into the volume of drinking water that will be drunk
within about 2-3 hours.
Continuous treatment: The table below shows the guidelines for administering the
veterinary medicinal product, assuming consumption of 100 litres drinking water a day
based on a estimated water consumption of 1 litre per 10 kg of body weight in pigs under 4
months and 0.66 litre per 10 kg of body weight in pigs over 4 months.
Pigs under 4 months:20 g powder/100 litres/dayPigs over 4 months:30 g powder/100 litres/day
In the case of continuous treatment, the medicated water must be changed twice daily.
AN: 01132/2024 and 01139/2024Page 4 of 6
Based on the recommended dose and the number and weight of animals to be treated, the
exact daily concentration of the veterinary medicinal product should be calculated
according to the following formula:
20 mg veterinary
medicinal product / kg
body weight day
x
average body weight (kg) of
animals to be treated
average daily water intake (l/animal)*
= mg veterinary medicinal
product per litre of
drinking water

* Prepare an amount of medicated water to be consumed within the next 12 hours. Any
unused medicated water should be discarded after 12 hours, and fresh medicated water -
for the next 12 hours - should be prepared
To ensure a correct dosage, body weight should be determined as accurately as possible.
The intake of medicated water depends on the clinical condition of the animals. In case of
insufficient uptake of water, pigs should be treated parenterally. In order to obtain the
correct dosage the concentration of amoxicillin has to be adjusted accordingly. The
maximum concentration of the pre-diluted medicated water is approximately 8 grams of
veterinary medicinal product per liters. The setting of the dosing device should be changed
accordingly.
Make sure the animals do not have access to non-medicated water during the period when
the medicated water is given. Once all the medicated water has been drunk, turn the
drinking water system back on. Discard any excess medicated water after 12 hours. The
use of suitably calibrated measuring equipment is recommended.

Do not use in cases of hypersensitivity to penicillin and other substances of the ß-lactam
group or to any of the excipients.
Do not use in rabbits and rodents such as guinea pig, hamster or gerbil.
Do not use in animals with serious kidney malfunction including anuria and oliguria.

Pigs:
Undetermined frequency (cannot
be estimated from the available
data)
Hypersensitivity reaction* (e.g. skin rash, anaphylactic
shock)
*Varying in severity. If suspected adverse reactions occur, treatment should be
discontinued.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
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either the marketing authorisation holder or its local representative or the national
competent authority via the national reporting system. See the package leaflet for
respective contact details.

None.
AN: 01132/2024 and 01139/2024Page 2 of 6

Special precautions for safe use in the target species:
Use of the veterinary medicinal product should be in accordance with official, national and
regional antimicrobial policies. Use of the veterinary medicinal product should be based on
identification and susceptibility testing of the target pathogen(s). If this is not possible,
therapy should be based on epidemiological information and knowledge of susceptibility of
the target pathogens at farm level, or at local/regional level. Use of the veterinary
medicinal product deviating from the instructions given in the SPC may increase the
prevalence of bacterial resistance to amoxicillin and may decrease its effectiveness of
treatment with amoxicillin, due to the potential for cross-resistance.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals
Penicillins and cephalosporins may cause hypersensitivity (allergy) following injection,
inhalation, ingestion or skin contact. Hypersensitivity to penicillins may lead to cross
sensitivity to cephalosporins and vice versa. Allergic reactions to these substances may
occasionally be serious.
Do not handle this veterinary medicinal product if you know you are sensitised or if you
have been advised not to work with such preparations.
Handle this veterinary medicinal product with care to avoid exposure, taking all
recommended precautions. Do not smoke, eat or drink while handling the veterinary
medicinal product. During preparation and administration of the medicated drinking water,
skin contact with the veterinary medicinal product and inhalation of dust particles should
be avoided. Wear gloves and an appropriate dust mask when applying the veterinary
medicinal product. Wash hands and contaminated skin immediately after handling the
veterinary medicinal product.
In the event of eye or skin contact, rinse the affected area with large amounts of clean
water and if irritation occurs, seek medical attention.
If you develop symptoms following exposure such as skin rash, you should seek medical
advice and show this warning to the physician. Swelling of the face, lips or eyes, or
difficulty with breathing are more serious symptoms and require urgent medical attention.
Special precautions for the protection of the environment:
Not applicable.

The bactericidal effect of amoxicillin is counteracted by pharmaceuticals with a
bacteriostatic effect.

This veterinary medicinal product as packaged for sale does not require any special
storage conditions.
After opening/reconstitution:
Do not store above 25ºC.
Keep the bag tightly closed in order to protect from moisture.

Meat and offal: 2 days.
4.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.