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POM-V Prescription Required Companion Animal

Nobivac KC Nasal Drops, Lyophilisate and Solvent for Suspension for Dogs

Active ingredients: Bordetella bronchiseptica, Canine parainfluenza virus

Form

Drops

Species

Dogs

Manufacturer

Intervet International B.V.

VMD MA No.

06376/5014

What it's used for

Active immunisation of dogs against and canine parainfluenza virus for periods of increased risk to reduce clinical signs induced by B. bronchiseptica and...

Full indications, dosage and side effects ↓
View official SPC (PDF)

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Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Nobivac KC Nasal Drops, Lyophilisate and Solvent for Suspension for Dogs — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 26 Mar 2026.

Active immunisation of dogs against and canine
parainfluenza virus for periods of increased risk to reduce clinical signs induced by B.
bronchiseptica and canine parainfluenza virus and to reduce shedding of canine
parainfluenza virus.
Onset of immunity: for Bordetella bronchiseptica
for canine parainfluenza virus: 3 weeks after vaccination.
Duration of immunity: 1 year.
None.
Dogs:
Very common
(>1 animal / 10 animals treated):
Nasal discharge
.
Ocular discharge
.
Common
(1 to 10 animals / 100 animals
reacted):
Sneezing
,
cough
.
Very rare
(<1 animal / 10,000 animals treated,
including isolated reports):
Wheezing
.
Lethargy.
Vomiting.
Hypersensitivity reaction, anaphylactic-type
reaction
.
Immune mediated haemolytic anaemia,
immune mediated thrombocytopenia,
immune mediated polyarthritis.
Particularly observed in very young susceptible puppies. Signs are generally mild and
transient, but in occasional cases may persist for up to four weeks. In animals, which show
more severe signs, appropriate antibiotic treatment may be indicated.
Such reaction may evolve to a more severe condition, which may be life-threatening. If such
reaction occurs appropriate treatment should be administered without delay.

Revised: November 2024
AN: 01917/2024
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or the national competent authority via the
national reporting system. See the package leaflet for respective contact details.
Vaccinate healthy animals only.

Revised: November 2024
AN: 01917/2024

Special precautions for use in animals
Vaccinated dogs may excrete the Bordetella bronchiseptica vaccine strain up to 6
weeks and the canine parainfluenza vaccine strain up to a few days following
vaccination. During this time, the contact of immunosuppressed and unvaccinated
dogs with vaccinated dogs should be avoided.
Immunosuppressive medication may impair the development of active immunity and
may increase the chance of adverse effects caused by the live vaccine strains.
Cats, pigs and unvaccinated dogs may react to the vaccine strains with mild and
transient respiratory signs. Other animals, like rabbits and small rodents have not
been tested.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals
Immunocompromised persons are advised to avoid contact with the vaccine and
vaccinated animals up to 6 weeks after vaccination.
Disinfect hands and equipment after use.
Special precautions for the protection of the environment
Not applicable.
Other precautions
Not applicable.
Do not administer in conjunction with other intranasal treatments or during antibiotic
treatment.
Safety and efficacy data are available which demonstrate that this vaccine can be
administered on the same day, but not mixed, with the live vaccines of the Nobivac
series against canine distemper, canine contagious hepatitis caused by canine
adenovirus type 1, canine parvovirus disease (based on strain 154) and respiratory
disease caused by canine adenovirus type 2, where authorised, and inactivated
vaccines of the Nobivac series against canine leptospirosis caused by all or some of
the following serovars: L. interrogans serogroup Canicola serovar Canicola,
L. interrogans serogroup Icterohaemorrhagiae serovar Copenhageni,
serogroup Australis serovar Bratislava, and L. kirschneri
serovar Bananal/Liangguang.
Safety data are available which demonstrate that this vaccine can be administered on
the same day but not mixed with the bivalent puppy vaccine of the Nobivac series
that contains canine parvovirus strain 630a. Efficacy of this vaccine after concurrent
use has not been tested. Therefore, while safety of concurrent use has been
demonstrated, the veterinarian should take this into account when deciding to
administer the products at the same time.
In very rare cases a transient acute hypersensitivity reaction may occur when this
product is used with other vaccines.
No information is available on the safety and efficacy of this vaccine when used with
any other veterinary medicinal product except the products mentioned above. A
decision to use this vaccine before or after any other veterinary medicinal product
therefore needs to be made on a case by case basis.
In case antibiotics are administered within one week after vaccination, the
vaccination should be repeated after the antibiotic treatment is finished.
Store and transport refrigerated (2 C – 8 C).
Do not freeze. Protect from light.
TCID50
1
colony forming units
Tissue Culture Infective Dose 50%
Excipients:
For the full list of excipients, see section

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.

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