POM-V Prescription Required

Nobilis Rhino CV Lyophilisate for Oculonasal Suspension for Chickens

Active ingredient: Avian pneumovirus

Form

Lyophilisate

Species

Chickens

Manufacturer

Intervet International B.V.

VMD MA No.

06376/3061

What it's used for

Broilers, future layers and breeders Active immunisation in order to reduce the frequency and the severity of clinical signs due to infection with avian rh...

Full indications, dosage and side effects ↓

View official SPC (PDF)

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Paying less for Avian pneumovirus

1

Ask your vet for a written prescription

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2

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Prescription required

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Clinical information

Nobilis Rhino CV Lyophilisate for Oculonasal Suspension for Chickens — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

Broilers, future layers and breeders
Active immunisation in order to reduce the frequency and the severity of clinical signs due
to infection with avian rhinotracheitis virus (avian metapneumovirus).
Onset of immunity: 3 weeks.
Duration of immunity: 16 weeks post-vaccination.
Future layers and breeders
Priming with Nobilis Rhino CV, followed by a second vaccination with an inactivated
vaccine containing the avian rhinotracheitis virus strain But1#8544 before the onset of lay
results in a reduction of the clinical signs including egg drop, caused by infection with
avian rhinotracheitis virus. Protective immunity is maintained for the normal laying period.

Oculonasal route
Reconstitute the freeze-dried vaccine in clean, disinfectant- and antiseptic-free water to
which 2% liquid skimmed milk is added and administer by means of a standardised
dropper. The amount of fluid required for eye- or nose-drop administration depends on the
number of doses and the droplet size, but approximately 35 ml per 1 000 doses is used.
Apply one drop in a nare or eye. Check that the drop is entirely absorbed before releasing
the bird.
After reconstitution the suspension looks homogeneous opalescent to slightly white.
Spray vaccination
The vaccine must be reconstituted with clean, disinfectant- and antiseptic-free water to
which 2% of liquid skimmed milk is added. The appropriate number of vials must be
opened under water. The volume of vaccine suspension must be sufficient to ensure a
homogeneous vaccination of the birds.
Depending on the age of the chickens to be vaccinated and the rearing system, take 250
to 500 ml of water per 1 000 doses. The vaccine suspension is to be sprayed evenly over
the appropriate number of animals at a distance of 30-40 cm with a regular spraying
apparatus, preferably when the animals sit together under a dim light. The spray apparatus
must be free from sediments, corrosion and traces of disinfectants and ideally should be
used for vaccination purposes only.
If applicable, reduce ventilation to prevent loss of spray.
After reconstitution the suspension looks clear.

None.

Chicken:
Common
(1 to 10 animals / 100 animals
treated):
Nasal discharge
, Cough
1
Mild. Between 2 to 7 days after administration for 1 to 2 days.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or the national competent authority via the
national reporting system. See the package leaflet for respective contact details.

Vaccinate healthy animals only.

Special precautions for safe use in the target species:
In order to reduce the circulation of the vaccine strain, all susceptible animals on the site
have to be vaccinated properly and preferably at the same time. The vaccine virus can
spread to other susceptible species with which they have direct contact. It was shown that
the spreading has negligible impact on turkeys, which together with chickens constitute the
species that are most susceptible to avian rhinotracheitis virus.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals:
Not applicable.

Safety and efficacy data are available which demonstrate that this vaccine can be
administered on the same day but not mixed with vaccines against infectious bronchitis
containing strain H120 and against Newcastle disease containing strains Clone 30 or C2
and infectious bronchitis vaccine (strain IB Ma5) when given on day 1 (the efficacy of
the IB Ma5 vaccine has not been investigated).
The company’s live vaccine against Gumboro disease (infectious bursal disease)
containing the D78 strain can be given 7 days after Nobilis Rhino CV.
No information is available on the safety and efficacy of this vaccine when used with any
other veterinary medicinal product except the products mentioned above.
A decision to use this vaccine before or after any other veterinary product therefore needs
to be made on a case by case basis.

Store in a refrigerator (2°C to 8°C).
Do not freeze
Keep the vial in the outer carton in order to protect from light.

Zero days.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.