POM-V Prescription Required

Nobilis REO Inac Emulsion for Injection for Chickens

Active ingredient: Avian reovirus

Form

Injection

Species

Chickens

Manufacturer

Intervet International B.V.

VMD MA No.

06376/4133

What it's used for

Onset of immunity: Active immunity develops in the parent within 4 weeks, and offspring born at any stage of the subsequent laying period will have passive...

Full indications, dosage and side effects ↓

View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Avian reovirus

1

Ask your vet for a written prescription

They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

Fill it at a registered online retailer

The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

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Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Nobilis REO Inac Emulsion for Injection for Chickens — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

Onset of immunity: Active immunity develops in the parent within 4 weeks, and offspring
born at any stage of the subsequent laying period will have passive immunity against
reovirus infections.
Duration of immunity: Offspring born to a vaccinated parent at any stage of the
subsequent laying period will have passive immunity against reovirus infections for
protection during the susceptible period in the early phase of life.
AN: 04335/2024Page 2 of 5

The veterinary medicinal product should be given to birds around 10–20 weeks of age
but not later than 4 weeks before the expected onset of lay.
Dose: 0.5 ml vaccine per bird by intramuscular injection into the thigh or chest muscle or
by subcutaneous injection into the back of the neck, using a medium sized needle (20 g x
½”). For an optimal response in birds not primed by field virus, two vaccinations should
be given approximately 6 weeks apart.
Allow the vaccine to reach ambient temperature (15 C – 25 C) before use.
The vaccine may occasionally separate into two layers on storage. This in no way affects
its potency, but the vaccine should be shaken vigorously before and during use to ensure
a good emulsification.
An automatic injection system, incorporating a means to prevent back flushing and hence
possible contamination of the vaccine, should be used to administer the vaccine.
Ensure that vaccination equipment is clean and sterile before use. Do not use
vaccination equipment with rubber parts as the excipient may damage certain types of
rubber.

None.

Chickens (for reproduction):
Very common
(>1 animal / 10 animals treated):
Injection site swelling
.
A slight transient swelling may be observed which resolves within 3 weeks and may be
palpable at the site of vaccination in 50% of vaccinated birds.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or its local representative or the national
competent authority via the national reporting system. See the package leaflet for
respective contact details.
AN: 04335/2024Page 3 of 5

Vaccinate healthy animals only.

Special precautions for safe use in the target species:
Not applicable.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals:
To the user:
This veterinary medicinal product contains mineral oil. Accidental injection/self-injection
may result in severe pain and swelling, particularly if injected into a joint or finger, and in
rare cases could result in the loss of the affected finger if prompt medical attention is not
given. If you are accidentally injected with this veterinary medicinal product, seek prompt
medical advice even if only a very small amount is injected and take the package leaflet
with you. If pain persists for more than 12 hours after medical examination, seek medical
advice again.
To the physician:
This veterinary medicinal product contains mineral oil. Even if small amounts have been
injected, accidental injection with this veterinary medicinal product can cause intense
swelling, which may, for example, result in ischaemic necrosis and even the loss of a
digit. Expert, PROMPT, surgical attention is required and may necessitate early incision
and irrigation of the injected area, especially where there is involvement of finger pulp or
tendon.
Special precautions for the protection of the environment:
Not applicable.

Safety and efficacy data are available which demonstrate that this vaccine can be
administered on the same day but not mixed with other Intervet inactivated oil emulsion
vaccines, containing the avian infectious bronchitis (IB), Gumboro disease (GD),
Newcastle disease (ND), turkey rhinotracheitis (TRT) and/or egg drop syndrome (EDS)
antigens.
No information is available on the safety and efficacy of this vaccine when used with any
other veterinary medicinal product except the products mentioned above. A decision to
use this vaccine before or after any other veterinary medicinal product therefore needs to
be made on a case-by-case basis.

Store in a refrigerator (2 C – 8 C).
Do not freeze.
Protect from light.

Zero days.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.