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POM-V Prescription Required

Nobilis IB Primo QX

Active ingredient: Infectious bronchitis virus

Form

Lyophilisate

Species

Chickens

Manufacturer

Intervet International B.V.

VMD MA No.

EU/2/14/174/001-009

What it's used for

For active immunisation of chickens in order to reduce respiratory signs of avian infectious bronchitis caused by QX-like variants of infectious bronchitis...

Full indications, dosage and side effects ↓
View official SPC (PDF)

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Paying less for Infectious bronchitis virus

  1. 1

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    They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.

  2. 2

    Fill it at a registered online retailer

    The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Nobilis IB Primo QX — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

For active immunisation of chickens in order to reduce respiratory signs of avian
infectious bronchitis caused by QX-like variants of infectious bronchitis virus
(IBV).
Onset of immunity: 3 weeks.
Duration of immunity: 8 weeks.
None.

Revised: September 2024
AN: 02637/2023
Chickens:
Very rare
(<1 animal / 10,000 animals
treated, including isolated
reports):
Respiratory signs
, Nasal discharge
1
Mild transient respiratory reaction that may occur for at least 10 days after
vaccination.

Revised: September 2024
AN: 02637/2023
Reporting adverse events is important. It allows continuous safety monitoring of
a veterinary medicinal product. Reports should be sent, preferably via a
veterinarian, to either the marketing authorisation holder or the national
competent authority via the national reporting system. See the package leaflet
for respective contact details.
Vaccinate healthy animals only.
The vaccine has been demonstrated to provide protection against QX-like
variant. The protection against other circulating IB strains has not been
investigated.

Special precautions for use in animals
All chickens on the site should be vaccinated at the same time.
The vaccine virus is capable of spreading to in contact birds for a minimum of
20 days after vaccination and appropriate care should be taken to separate
vaccinated from non-vaccinated chickens. During this time, the contact of
immunosuppressed and unvaccinated chickens with vaccinated chickens
should be avoided. Precautionary measures should be taken to prevent
spreading to wildlife. The premises must be cleaned and disinfected after each
production round.
This vaccine should only be used after it has been established that the QX-like
IBV variant strain is epidemiologically relevant. It is important to avoid
introduction of the IB D388 vaccine virus into premises in which the wild type
strain is not present. The IB D388 vaccine should only be applied in hatcheries
to chickens from 1 day of age or older if adequate controls are in place to avoid
the spread of the vaccine virus to birds that will be transported to non-IB QX
exposed flocks.
Special precautions to be taken by the person administering the veterinary
medicinal product to animals
In case of coarse spray, personal protective equipment consisting of masks with
eye protection should be worn when handling the veterinary medicinal product.
Wash and disinfect hands and equipment after vaccination to avoid the spread
of the virus.
Special precautions for the protection of the environment
Not applicable.
Other precautions
Not applicable.
Safety and efficacy data are available which demonstrate that this vaccine can
be mixed and administered with Nobilis IB Ma5 for spray or oculonasal
application. Simultaneous use of both vaccines increases the risk of
recombination of viruses and potential emergence of new variants. However,
the chance of a hazard occurring has been estimated very low. For the mixed
products the onset of immunity is 3 weeks and the duration of immunity is 8
weeks for the claimed protection against Massachusetts and QX-like strains of
IBV. The safety parameters of the mixed vaccines are not different from those
described for the vaccines administered separately. Read the product
information of Nobilis IB Ma5 before use.
No information is available on the safety and efficacy of this vaccine when used
with any other veterinary medicinal product except the product mentioned
above. A decision to use this vaccine before or after any other veterinary
medicinal product therefore needs to be made on a case by case basis.
Lyophilisate:
Store in a refrigerator (2 C – 8 C).
Do not freeze.
Protect from light.
Solvent:
Store below 25 °C.
Do not freeze.
EID50
1
EID50: 50% egg infective dose- the virus titre required to produce infection in
50% of the eggs inoculated
For the full list of excipients, see section

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.

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