POM-VPS Prescription Required

Nobilis IB + ND + EDS Emulsion for Injection for Chickens

Active ingredients: Avian infectious bronchitis virus, Egg drop syndrome virus, Newcastle disease virus

Form

Injection

Species

Chickens

Manufacturer

Intervet International B.V.

VMD MA No.

06376/4132

What it's used for

The vaccine is recommended for the vaccination of laying and breeding birds to:  of avian infectious bronchitis virus (IBV), and reduce infection in prime...

Full indications, dosage and side effects ↓

View official SPC (PDF)

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Paying less for Avian infectious bronchitis...

1

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They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

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Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Nobilis IB + ND + EDS Emulsion for Injection for Chickens — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 26 Mar 2026.

The vaccine is recommended for the vaccination of laying and breeding birds to:

of avian infectious bronchitis virus (IBV), and reduce infection in primed birds.

disease virus (NDV).

drop syndrome ’76 virus (EDSV).
Onset of immunity: Active immunity develops within 4 weeks.
Duration of immunity: One laying period (for avian infectious bronchitis and Newcastle
disease viruses, this requires birds to have been adequately primed with live vaccines

Revised: January 2025
AN: 02224/2024
against these pathogens during the growing phase).

Dose: 0.5 ml per bird.
Routes of administration: Intramuscular injection in the thigh or chest muscle, or by
subcutaneous injection in the back of the neck, using a medium sized needle (20 G x ½”).
Nobilis IB+ND+EDS should be given to birds around 14–20 weeks of age but not less than
4 weeks before the expected onset of lay.
Priming with live vaccines for avian infectious bronchitis and Newcastle disease viruses is
necessary unless serological tests indicate otherwise. The interval between priming and
booster should not be less than 4 weeks and preferably more than 6 weeks.
Allow the vaccine to reach ambient temperature (15–25 °C) before use.
The vaccine may occasionally separate into two layers on storage. This in no way affects its
potency. Shake the bottle vigorously before and periodically during use.
An automatic injection system, incorporating a means to prevent back-flushing and hence
possible contamination of the vaccine, should be used for administration.
Ensure that vaccination equipment is clean and sterile before use. Do not use vaccination
equipment with rubber parts as the excipient may attack certain types of rubber.

None.

A mild transient swelling may be observed at the injection site for 2 weeks.

Vaccinate healthy birds only.
A good immune response is reliant on the reaction of an immunogenic agent and a fully
competent immune system. Immunogenicity of the vaccine antigen will be reduced by poor
storage or inappropriate administration. Immuno-competence of the animal may be
compromised by a variety of factors including poor health, nutritional status, genetic factors,
concurrent drug therapy and stress. Under certain conditions, for example extreme disease
pressure, fully immune birds may succumb to disease. Therefore successful vaccination
may not be synonymous with full protection in the face of a disease challenge.

Special precautions for the use in animals
None.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals
To the user:
This veterinary medicinal product contains mineral oil. Accidental self-injection may result in
severe pain and swelling, particularly if injected into a joint or finger, and in rare cases could
result in the loss of the affected finger if prompt medical attention is not given.
If you are accidentally injected with this product, seek prompt medical advice even if only a
very small amount is injected and take the package leaflet with you.
If pain persists for more than 12 hours after medical examination, seek medical advice
again.
To the physician:
This veterinary medicinal product contains mineral oil. Even if small amounts have been
injected, accidental injection with this product can cause intense swelling, which may, for
example, result in ischaemic necrosis and even the loss of a digit. Expert, PROMPT,
surgical attention is required and may necessitate early incision and irrigation of the injected
area, especially where there is involvement of finger pulp or tendon.

Safety and efficacy data are available which demonstrate that this vaccine can be
administered on the same day but not mixed with Nobilis TRT inac, an Intervet inactivated
vaccine containing TRT antigen strain But1#8544 (subgroup A).
No information is available on the safety and efficacy of this vaccine when used with any
other veterinary medicinal product except the product mentioned above. A decision to use
this vaccine before or after any other veterinary medicinal product therefore needs to be
decided on a case-by-case basis.

Store in refrigerator (2 °C – 8 °C). Do not freeze.
Protect from light.

Zero days.
5. IMMUNOLOGICAL PROPERTIES
Pharmacotherapeutic group: Immunologicals for Aves, domestic fowl, inactivated viral
vaccines.
ATCvet code: QI01AA13.
To stimulate active immunity against avian infectious bronchitis, Newcastle disease and egg
drop syndrome ’76 viruses.

Revised: January 2025
AN: 02224/2024

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.