Nobilis IB 4-91 Lyophilisate for Oculonasal Suspension/use in Drinking Water for Chickens
Active ingredient: Infectious bronchitis virus
Form
Lyophilisate
Species
Manufacturer
MSD Animal Health UK Limited
VMD MA No.
01708/5043
What it's used for
Active immunisation of chickens to reduce the respiratory signs of infectious bronchitis caused by the IBV variant strain 4-91. Onset of immunity: 3 weeks....
Full indications, dosage and side effects ↓The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.
Paying less for Infectious bronchitis virus
-
1
Ask your vet for a written prescription
They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
-
2
Fill it at a registered online retailer
The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.
Done — we'll email you when prices land.
Prescription required
Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.
Nobilis IB 4-91 Lyophilisate for Oculonasal Suspension/use in Drinking Water for Chickens — SPC Details
Source: VMD Summary of Product Characteristics (SPC). Last updated 26 Mar 2026.
bronchitis caused by the IBV variant strain 4-91.
Onset of immunity: 3 weeks.
Duration of immunity: 6 weeks.
Revised: January 2024
AN: 03422/2022
Very common
(>1 animal / 10 animals
treated):
Respiratory signs
1
May persist for a few days.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
Revised: January 2024
AN: 03422/2022
either the marketing authorisation holder or the national competent authority via the
national reporting system. See the package leaflet for respective contact details.
Special precautions for use in animals
Nobilis IB 4-91 is intended to protect chickens against respiratory signs of disease
caused by IBV variant strain 4-91 only and should not be used as a replacement for
other IBV vaccines.
The product should only be used after it has been established that IBV variant strain
4-91 is epidemiologically relevant in the area. Care should be taken to avoid the
introduction of the variant strain into an area where it is not present.
Care should be taken to avoid spread of the vaccine virus from vaccinated chickens
to pheasants.
The vaccine virus may spread from vaccinated to non-vaccinated chickens and
appropriate care should be taken to separate vaccinated from non-vaccinated
chickens.
Wash and disinfect hands and equipment after vaccinating to avoid spread of the
virus.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals
In case of spray administration, personal protective equipment consisting of masks
with eye protection should be worn when handling the veterinary medicinal product.
Special precautions for the protection of the environment:
Not applicable.
Other precautions
Not applicable.
-
intranasal/ocular administration to commercial chicks from one day of age
onwards. For the mixed products the onset of immunity is 3 weeks, and the
duration of immunity is 6 weeks for the claimed protection against
Massachusetts and variant strain 4-91 of IBV. The safety parameters of the
mixed vaccines are not different from those described for the vaccines
administered separately. Simultaneous use of both vaccines increases the risk
of recombination of viruses and potential emergence of new variants. However,
the chance of a hazard occurring has been estimated very low and is minimized
by routinely vaccinating all chickens on the premise at the same time and
cleaning and disinfection after each production round. Read the product
information of Nobilis IB Ma5 before use.
-
by the subcutaneous or in ovo route with Innovax-ND-IBD.
-
by the subcutaneous or in ovo route with Innovax-ND-ILT
Nobilis IB 4-91 given at day-old can adversely affect the efficacy of turkey
rhinotracheitis (TRT) vaccine given within 7 days.
No information is available on the safety and efficacy of this vaccine when used with
any other veterinary medicinal product. A decision to use this vaccine before or after
any other veterinary medicinal product therefore needs to be made on a case by
case basis.
Do not freeze.
Protect from light.
5. IMMUNOLOGICAL PROPERTIES
Pharmacotherapeutic group: Immunologicals for Aves, domestic fowl, live viral
vaccine, avian infectious bronchitis virus.
ATCvet code: QI01AD07.
Active immunisation against avian infectious bronchitis virus (IBV) variant strain IB 4-
91 which causes infectious bronchitis in chickens.
This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.
Medication costs adding up?
Pet insurance can cover prescription medications. Find the right policy for your pet.
Other Products Containing Infectious bronchitis virus
These products share the same active ingredient and may be suitable alternatives. Always consult your vet.
Avishield IB GI-13, Lyophilisate for Oculonasal Suspension/Use in Drinking Water for Chickens
POM-VIZO S.r.l a socio unico
Avishield IB GI-13, Lyophilisate for Oculonasal Suspension/Use in Drinking Water for Chickens
POM-VIZO S.r.l a socio unico
Avishield IB H120, Lyophilisate for Oculonasal Suspension/Use in Drinking Water for Chickens
POM-VIZO S.r.l a socio unico
Avishield IB H120, Lyophilisate for Oculonasal Suspension/Use in Drinking Water for Chickens
POM-VIZO S.r.l a socio unico
CEVAC IBird Lyophilisate for Oculonasal Suspension/Use in Drinking Water for Chickens
POM-VCeva Sante Animale
CEVAC IBird Lyophilisate for Oculonasal Suspension/Use in Drinking Water for Chickens
POM-VCeva Sante Animale
Alternative options to consider
Retailers we earn a commission from. It costs you nothing and never changes what we show.
The Pharm Pet Co. — Pet Pharmacy
UK online pet pharmacy. Flea, worm, prescription medications, supplements and pet food. Save vs vet prices.
Pet Care at Pharmacy2U
The UK's largest online pharmacy. Pet wormers, flea treatments, dental and joint care. Free delivery on orders over £30.
KatKin Fresh Cat Food
The UK's top-rated cat food. 100% fresh, human-quality meat, gently cooked and delivered frozen. Vet-formulated for every life stage.
We may earn a small commission if you purchase through these links, at no extra cost to you.
Related Medications
Aftopur AlSap
POM-VFoot-and-mouth disease virus
Aftopur AlSap
POM-VFoot-and-mouth disease virus
Aftopur DOE
POM-VFoot-and-mouth disease virus
Aftopur DOE
POM-VFoot-and-mouth disease virus
Alpha Ject Micro 1 PD Emulsion for Injection for Atlantic Salmon
POM-VSalmon pancreas disease virus
Alpha Ject Micro 1 PD Emulsion for Injection for Atlantic Salmon
POM-VSalmon pancreas disease virus
Find cheaper vets near you
Compare vet consultation prices in your area. Save on procedures and get a prescription to buy medications online.