POM-V Prescription Required

Marbosyva 100 mg/ml Solution for Injection for Cattle and Pigs

Active ingredient: Marbofloxacin

Form

Injection

Species

Cattle Pigs

Manufacturer

Laboratorios SYVA S.A.

VMD MA No.

31592/3004

What it's used for

In pigs (sows): - Treatment of Postpartum Dysgalactiae Syndrome, PDS (Metritis Mastitis Agalactia Syndrome) caused by marbofloxacin-susceptible bacterial s...

Full indications, dosage and side effects ↓

View official SPC (PDF)

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Paying less for Marbofloxacin

1

Ask your vet for a written prescription

They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

Fill it at a registered online retailer

The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

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Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Marbosyva 100 mg/ml Solution for Injection for Cattle and Pigs — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

In pigs (sows):
- Treatment of Postpartum Dysgalactiae Syndrome, PDS (Metritis Mastitis Agalactia
Syndrome) caused by marbofloxacin-susceptible bacterial strains.

cattle.
Respiratory infections:
The recommended dosage is 8 mg marbofloxacin/kg body weight (2 ml veterinary
medicinal product/25 kg body weight) in a single injection by the intramuscular route.
If the volume to be injected is more than 20 ml, it should be divided between two or
more injection sites.
In cases of respiratory infections caused by , the recommended
dose is 2 mg marbofloxacin/kg body weight (1 ml veterinary medicinal product/50 kg
body weight), in a single daily injection for 3 to 5 consecutive days, by the
intramuscular or subcutaneous route. The first injection may be given by the
intravenous route.
Acute mastitis:
The recommended dosage is 2 mg marbofloxacin/kg body weight (1 ml veterinary
medicinal product/50 kg body weight) in a single daily injection, by the subcutaneous
or intramuscular route, for 3 consecutive days. The first injection may be given by the
intravenous route.
Pigs (sows):
The recommended dosage is 2 mg marbofloxacin/kg bodyweight (1 ml veterinary
medicinal product/50 kg body weight) in a single daily injection by the intramuscular
route, for 3 consecutive days.
In cattle and pigs, the preferred injection site is the neck area.
To ensure a correct dosage bodyweight should be determined as accurately as
possible to avoid underdosing.
In order to reduce the risk of particulate contamination of the product, it is
recommended that a draw-off needle be used to reduce the number of times the
septum is punctured.
As the vial cannot be broached more than 50 times, the user should choose the most
appropriate vial size according to the target species to treat.

Do not use in cases where the pathogen involved is resistant to other
fluoroquinolones (cross resistance).
Do not use in cases of hypersensitivity to the active substance, to any other
quinolone or to any of the excipients.

Cattle and pigs:
Very rare
(<1 animal / 10,000 animals
treated, including isolated reports):
Injection site lesion
1,2
Injection site reactions (such as pain and
swelling)
1
Inflammatory lesions following subcutaneous administration.
Following intramuscular administration, may persist for at least 12 days after
injection..
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder <or its local representative> or the national
competent authority via the national reporting system. See the package leaflet for
respective contact details.

None.

Special precautions for safe use in the target species:
Official and local antimicrobial policies should be taken into account when the product
is used.
Fluoroquinolones should be reserved for the treatment of clinical conditions which
have responded poorly, or are expected to respond poorly, to other classes of
antimicrobials.
Whenever possible, fluoroquinolones should only be used based on susceptibility
testing.
Use of the product deviating from the instructions given in the SPC may increase the
prevalence of bacteria resistant to the fluoroquinolones and may decrease the
effectiveness of treatment with other quinolones due to the potential for cross
resistance.
The efficacy data showed that the product has insufficient efficacy for the treatment
of acute forms of mastitis induced by gram-positive bacteria.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals:
People with known hypersensitivity to (fluoro)quinolones should avoid contact with
the veterinary medicinal product.
Care should be taken to avoid accidental self-injection, it can induce a slight irritation.
In case of accidental self-injection, seek medical advice immediately and show the
package leaflet or the label to the physician.
In case of contact with skin or eyes, rinse with plenty of water.
Wash hands after use.
Special precautions for the protection of the environment:
Not applicable.

None known.

Do not freeze.
Keep the vial in the outer carton in order to protect from light.

Cattle:
IndicationRespiratoryMastitis
Dosage
2 mg/kg for 3 to 5
days (IV/IM/SC)
8 mg/kg on a single
occasion (IM)
2mg/kg for 3 days
(IV/IM/SC)
Meat and offal6 days3 days6 daysMilk36 hours72 hours36 hours
Pigs:
Meat and offal: 4 days

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.