POM-V Prescription Required

Marbiflox 100 mg/ml Solution for Injection for Cattle and Pigs (Sows)

Active ingredient: Marbofloxacin

Form

Injection

Species

Cattle Pigs

Manufacturer

KRKA, d.d., Novo mesto

VMD MA No.

01656/4023

What it's used for

- Treatment of acute forms of mastitis induced by marbofloxacin-sensitive Escherichia coli strains, during lactation. In pigs: - Treatment of the Metritis...

Full indications, dosage and side effects ↓

View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Marbofloxacin

1

Ask your vet for a written prescription

They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

Fill it at a registered online retailer

The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Your prescription rights → VMD register of retailers →

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Marbiflox 100 mg/ml Solution for Injection for Cattle and Pigs (Sows) — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

- Treatment of acute forms of mastitis induced by marbofloxacin-sensitive Escherichia coli
strains, during lactation.
In pigs:
- Treatment of the Metritis Mastitis Agalactia syndrome caused by marbofloxacin-sensitive
bacterial strains.

medicinal product/25 kg bodyweight in a single injection.
If the volume to be injected is more than 20 ml, it should be divided between two or more
injection sites.
Acute mastitis:
- Intramuscular or subcutaneous use:
The recommended dosage is 2 mg marbofloxacin /kg i.e. 1 ml of the veterinary medicinal
product /50 kg bodyweight in a single daily injection, for 3 days.
The first injection may also be given by the intravenous route too.
Pigs (sows):
- Intramuscular use:
The recommended dosage is 2 mg marbofloxacin /kg i.e. 1 ml of the veterinary medicinal
product /50kg bodyweight in a single daily injection, for 3 days.
The cap may be safely punctured up to 25 times. The user should choose the most
appropriate vial size according to the target species to treat.

Do not use in cases where the pathogen involved is resistant to other fluoroquinolones
(cross resistance).
AN: 03385/2024 & 03386/2024
Do not use in cases of hypersensitivity to marbofloxacin or any other quinolone or to any of
the excipients.

Cattle and pigs:
Undetermined frequency
(cannot be estimated from the
available data)
Injection site reaction
1,2
(e.g. injection site pain,
injection site oedema), injection site inflammation
1,3
Arthropathy
1
After intramuscular injection
Transient
Can persist for at least 12 days after injection.
It has never been observed with marbofloxacin in cattle.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or its local representative or the national
AN: 03385/2024 & 03386/2024
competent authority via the national reporting system. See the package leaflet for
respective contact details.

None.

Special precautions for safe use in the target species:
Official and local antimicrobial policies should be taken into account when the veterinary
medicinal product is used.
Fluoroquinolones should be reserved for the treatment of clinical conditions which have
responded poorly, or are expected to respond poorly, to other classes of antimicrobials.
Whenever possible, fluoroquinolones should only be used based on susceptibility testing.
Use of the veterinary medicinal product deviating from the instructions given in the SPC
may increase the prevalence of bacteria resistant to the fluoroquinolones and may
decrease the effectiveness of treatment with other quinolones due to the potential for cross
resistance.
The efficacy data showed that the veterinary medicinal product has insufficient efficacy for
the treatment of acute forms of mastitis induced by gram-positive bacteria.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals:
People with known hypersensitivity to (fluoro)quinolones should avoid contact with the
veterinary medicinal product.
Care should be taken to avoid accidental self injection.
In case of accidental self injection, seek medical advice immediately and show the
package leaflet or the label to the physician.
Accidental self-injection can induce a slight irritation.
In case of contact with skin or eyes, rinse with plenty of water.
Wash hands after use.
Special precautions for the protection of the environment:
Not applicable.

None known.

Store in the original package in order to protect from light.
Do not freeze.

Cattle:
8 mg/kg single dose:
Meat and offal: 3 days
Milk: 72 hours
2 mg/kg single daily injection, for 3 days:
Meat and offal: 6 days
Milk: 36 hours
Pigs (sows):
Meat and offal: 4 days

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.