Kesium 500 mg / 125 mg Chewable Tablets for Dogs
Active ingredients: Amoxicillin, Clavulanic Acid
Form
Chewable
Species
Manufacturer
Ceva Sante Animale
VMD MA No.
14966/5067
What it's used for
- Respiratory tract infections associated with Pasteurella spp. - Digestive tract infections associated with - Infections of the oral cavity (mucous membra...
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Prescription required
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Kesium 500 mg / 125 mg Chewable Tablets for Dogs — SPC Details
Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.
Pasteurella spp.
- Digestive tract infections associated with
- Infections of the oral cavity (mucous membrane) associated with
Streptococcus spp Escherichia coli.
clavulanic acid per kg body weight twice a day by the oral route in dogs, i.e. 1 tablet per
50 kg body weight every 12 h, according to the following table:
Body weight (kg)Number of tablets to be administered
twice daily
> 9 to 12.5¼12.6 to 20Use the 200mg / 50mg20.1 to 25 ½25.1 to 37.5¾37.6 to 50 150.1 to 62.51¼62.6 to 75 1½
In refractory cases, the dose may be doubled to 20 mg of amoxicillin / 5 mg clavulanic
acid/kg bodyweight twice daily, at the clinician’s discretion.
The chewable tablets are flavoured and are accepted by a majority of dogs. The
chewable tablets can be administered directly into the mouth of the animals or added to a
small quantity of food.
Duration of therapy
The majority of routine cases respond to 5 – 7 days of therapy.
In chronic cases, a longer case of therapy is recommended. In such circumstances
overall treatment length must be at the clinician’s discretion, but should be long enough to
ensure complete resolution of the bacterial disease.
To ensure the correct dosage, body weight should be determined as accurately as
possible.
Instruction on how to divide the tablet: Put the tablet on an even surface, with its scored
side facing down (convex face up). With the tip of the forefinger, exert slight vertical
pressure on the middle of the tablet to break it along its width into halves. Then, in order
to obtain quarters, exert slight pressure on the middle of one half with the forefinger to
break it into two parts.
group or to any excipients.
Do not use in animals with serious dysfunction of the kidneys accompanied by anuria and
oliguria.
Do not administer to gerbils, guinea pigs, hamsters, rabbits and chinchillas. Do not use in
horses and ruminating animals.
Do not use where resistance to this combination is known to occur.
Very rare
(<1 animal / 10,000 animals
treated, including isolated reports
):
Gastrointestinal signs (e.g. diarrhoea or vomiting)
Allergic reaction (e.g. allergic skin reaction,
anaphylaxis)
1
Treatment may be discontinued depending on the severity of the undesirable effects and
a benefit/risk evaluation by the veterinary surgeon.
In these cases, administration should be discontinued, and a symptomatic treatment
given.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or the national competent authority via the
national reporting system. See the package leaflet for respective contact details.
Special precautions for safe use in the target species:
Official, national and regional antimicrobial policies with respect to the use of broad-
spectrum antibiotics should be taken into account.
Do not use in case of bacteria sensitive to narrow spectrum penicillins or to amoxicillin
as single substance.
It is advised that upon initiating therapy appropriate sensitivity testing is performed and
that therapy is continued only after susceptibility to the combination has been
established.
Use of the veterinary medicinal product deviating from the instructions given in the SPC
may increase the prevalence of bacteria resistant to the amoxicillin/clavulanate, and may
decrease the effectiveness of treatment with beta-lactam antibiotics.
In animals with hepatic and renal dysfunction, the dosing regimen should be carefully
evaluated and the use of the veterinary medicinal product based on a risk/benefit
evaluation by the veterinary surgeon.
Caution is advised in the use in small herbivores other than those in the section 3.3.
The potential for allergic cross-reactions with other penicillin derivates and
cephalosporins should be considered.
The chewable tablets are flavoured. In order to avoid any accidental ingestion, store
tablets out of reach of the animals.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals
Penicillins and cephalosporins may cause hypersensitivity (allergy) following injection,
inhalation, ingestion or skin contact. Hypersensitivity to penicillins may lead to cross-
reactions to cephalosporins and vice versa. Allergic reactions to these substances may
occasionally be serious.
Do not handle this product if you know you are sensitised, or if you have been advised
not to work with such preparations.
Handle this product with great care to avoid exposure, taking all recommended
precautions.
If you develop symptoms following exposure such as a skin rash, you should seek
medical advice and show the doctor this warning. Swelling of the face, lips or eyes or
difficulty with breathing are more serious symptoms and require urgent medical attention.
Wash hands after use.
Special precautions for the protection of the environment:
Not applicable.
effect of penicillins because of the rapid onset of bacteriostatic action.
Penicillins may increase the effect of aminoglycosides.
Divided tablets should be stored in the blister pack.
This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.
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Other Products Containing Amoxicillin
These products share the same active ingredient and may be suitable alternatives. Always consult your vet.
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Amoxy Active 697 mg/g Oral Powder for Pigs and Chickens
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Amoxy Active 697 mg/g Oral Powder for Pigs and Chickens
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