POM-V Prescription Required Companion Animal

Kesium 50 mg / 12.5 mg Chewable Tablets for Cats and Dogs

Active ingredients: Amoxicillin, Clavulanic Acid

Form

Chewable

Species

Cats Dogs

Manufacturer

Ceva Sante Animale

VMD MA No.

14966/3065

What it's used for

- Respiratory tract infections associated with Pasteurella spp. - Digestive tract infections associated with - Infections of the oral cavity (mucous membra...

Full indications, dosage and side effects ↓

View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Amoxicillin + Clavulanic Aci...

1

Ask your vet for a written prescription

They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

Fill it at a registered online retailer

The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

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Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Kesium 50 mg / 12.5 mg Chewable Tablets for Cats and Dogs — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

- Respiratory tract infections associated with
Pasteurella spp.
- Digestive tract infections associated with
- Infections of the oral cavity (mucous membrane) associated with
Streptococcus spp Escherichia coli.

The recommended dose of the veterinary medicinal product is 10 mg amoxicillin /2.5 mg
clavulanic acid per kg body weight twice a day by the oral route in dogs and cats, i.e. 1
tablet per 5 kg body weight every 12 h, according to the following table:
Body weight
(kg)
Number of tablets twice daily>1.3 to 2.5½> 2.6 to 5.01> 5.1 to 7.51 ½> 7.6 to 10.02
In refractory cases the dose may be doubled to 20 mg of amoxicillin / 5 mg clavulanic
acid/kg bodyweight twice daily, at the clinician’s discretion.
The chewable tablets are flavoured and are accepted by a majority of cats and dogs.
The chewable tablets can be administered directly into the mouth of the animals or
added to a small quantity of food.
Duration of therapy
The majority of routine cases respond to 5 – 7 days of therapy.
In chronic cases, a longer case of therapy is recommended. In such circumstances
overall treatment length must be at the clinician’s discretion, but should be long enough
to ensure complete resolution of the bacterial disease.
To ensure the correct dosage, body weight should be determined as accurately as
possible.

Do not use in case of hypersensitivity to penicillins, to other substances of the β-lactam
group or to any excipients.
Do not use in animals with serious dysfunction of the kidneys accompanied by anuria and
oliguria.
Do not administer to gerbils, guinea pigs, hamsters, rabbits and chinchillas. Do not use
in horses and ruminating animals.
Do not use where resistance to this combination is known to occur.

Dogs, Cats:
Very rare
(<1 animal / 10,000 animals
treated, including isolated reports
):
Gastrointestinal signs (e.g. diarrhoea or vomiting)
Allergic reaction (e.g. allergic skin reaction,
anaphylaxis)
1
Treatment may be discontinued depending on the severity of the undesirable effects
and a benefit/risk evaluation by the veterinary surgeon.
In these cases, administration should be discontinued, and a symptomatic treatment
given.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or the national competent authority via the
national reporting system. See the package leaflet for respective contact details.

None.

Special precautions for safe use in the target species:
Official, national and regional antimicrobial policies with respect to the use of broad-
spectrum antibiotics should be taken into account.
Do not use in case of bacteria sensitive to narrow spectrum penicillins or to amoxicillin
as single substance.
It is advised that upon initiating therapy appropriate sensitivity testing is performed and
that therapy is continued only after susceptibility to the combination has been
established.
Use of the veterinary medicinal product deviating from the instructions given in the
SPC may increase the prevalence of bacteria resistant to the amoxicillin/clavulanate,
and may decrease the effectiveness of treatment with beta-lactam antibiotics.
In animals with hepatic and renal dysfunction, the dosing regimen should be carefully
evaluated and the use of the veterinary medicinal product based on a risk/benefit
evaluation by the veterinary surgeon.
Caution is advised in the use in small herbivores other than those in the section 3.3.
The potential for allergic cross-reactions with other penicillin derivates and
cephalosporins should be considered.
The chewable tablets are flavoured. In order to avoid any accidental ingestion, store
tablets out of reach of the animals.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals
Penicillins and cephalosporins may cause hypersensitivity (allergy) following injection,
inhalation, ingestion or skin contact. Hypersensitivity to penicillins may lead to cross-
reactions to cephalosporins and vice versa. Allergic reactions to these substances may
occasionally be serious.
Do not handle this product if you know you are sensitised, or if you have been advised
not to work with such preparations.
Handle this product with great care to avoid exposure, taking all recommended
precautions.
If you develop symptoms following exposure such as a skin rash, you should seek
medical advice and show the doctor this warning. Swelling of the face, lips or eyes or
difficulty with breathing are more serious symptoms and require urgent medical
attention.
Wash hands after use.
Special precautions for the protection of the environment:
Not applicable.

Chloramphenicol, macrolides, sulfonamides and tetracyclines may inhibit the antibacterial
effect of penicillins because of the rapid onset of bacteriostatic action.
Penicillins may increase the effect of aminoglycosides.

Do not store above 25°C.
Divided tablets should be stored in the blister pack.

Not applicable

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.