Ingelvac CircoFlex Suspension for Injection for Pigs

Single intramuscular injection of one dose (1 ml), irrespective of body weight.
Shake well before use.
Avoid introduction of contamination during use.
Vaccines devices should be used in accordance with the device instructions provided
by the manufacturer. After correct handling in accordance with the mixing instructions
no leakage should occur. In case of any leakage or incorrect handling of the product
the bottle should be discarded.
Avoid multiple broaching.
When mixed with Ingelvac MycoFLEX:
• Vaccinate only pigs as from 3 weeks of age.
• Cannot be administered in pregnant or lactating pigs.
When mixed with Ingelvac MycoFLEX the following equipment should be used:
• Use the same volumes of Ingelvac CircoFLEX and Ingelvac MycoFLEX.
• Use a pre-sterilised transfer needle. Pre-sterilised transfer needles (CE
certified) are commonly available via medical equipment suppliers.
To ensure correct mixing follow the steps as described below:
1. Connect one end of the transfer needle to the vaccine bottle of Ingelvac
MycoFLEX.
2. - Connect the opposite end of the transfer needle to the vaccine bottle of
Ingelvac CircoFLEX.
- Transfer the Ingelvac CircoFLEX vaccine into the vaccine bottle of Ingelvac
MycoFLEX. If needed, gently press the vaccine bottle of Ingelvac CircoFLEX to
facilitate the transfer.
- After the transfer of the full content of Ingelvac CircoFLEX, disconnect and
discard transfer needle and empty vaccine bottle of Ingelvac CircoFLEX.
3. To ensure appropriate mixing of the vaccines, gently shake the vaccine bottle of
Ingelvac MycoFLEX until the mixture is of uniform orange to reddish colour. During
vaccination the uniformity of the coloured mixture should be monitored and
maintained by continuous agitation.
4. Administer one single injection dose (2 ml) of the mixture intramuscularly per
pig, irrespective of body weight. For administration, vaccine devices should be used
in accordance with the device instructions provided by the manufacturer.
To ensure correct mixing with the TwistPak bottles follow the steps as described
below:
1. the red base of the bottle of Ingelvac MycoFLEX to uncover
the connection system. The red base could be used upside down as a stand to
position of the Ingelvac MycoFLEX bottle upside down.
Twist and remove the green base of the Ingelvac CircoFLEX bottle.
2. the connection ends of the two bottles until they engage.
3. the bottles together until they touch one another completely.
A click confirms that the bottles are engaged.
4. the two vaccine bottles clockwise to complete the coupling of both
bottles.
5. To ensure appropriate mixing, slowly invert the locked bottles until the mixture
is of uniform orange to reddish colour. During vaccination the uniformity of the
coloured mixture should be monitored and maintained by continuous agitation.
6. Administer one single injection dose (2 ml) of the mixture intramuscularly per
pig, irrespective of body weight. For administration, vaccine devices should be
used in accordance with the device instructions provided by the manufacturer.
Use the entire vaccine mixture immediately after mixing. Any unused mixture or
waste material should be disposed according to the instructions given in section 5.5.
When mixed with Ingelvac PRRSFLEX EU:
• Vaccinate only pigs as from 17 days of age.
• Cannot be administered in pregnant or lactating pigs.
When mixed with Ingelvac PRRSFLEX EU the following equipment should be used:
• Use the same volumes of Ingelvac CircoFLEX and Ingelvac PRRSFLEX EU.
• Ingelvac CircoFLEX hereby replaces the solvent of Ingelvac PRRSFLEX EU.
• Use a pre-sterilised transfer needle. Pre-sterilised transfer needles (CE
certified) are commonly available via medical equipment suppliers.
To ensure correct mixing follow the steps as described below:
1. Connect one end of the transfer needle to the vaccine bottle of Ingelvac
CircoFLEX.
2. Connect the opposite end of the transfer needle to the vaccine bottle of Ingelvac
PRRSFLEX EU.
3. Transfer the Ingelvac CircoFLEX vaccine into the vaccine bottle of Ingelvac
PRRSFLEX EU. If needed, gently press the vaccine bottle of Ingelvac
CircoFLEX to facilitate the transfer.
After the transfer of the full content of Ingelvac CircoFLEX, disconnect and
discard transfer needle and empty vaccine bottle of Ingelvac CircoFLEX.
4. To ensure appropriate mixing of the vaccines, gently shake the vaccine bottle of
Ingelvac PRRSFLEX until the cake is fully dissolved.
5. Administer one single injection dose (1 ml) of the mixture intramuscularly per
pig, irrespective of body weight. For administration, vaccine devices should be
used in accordance with the device instructions provided by the manufacturer.
Use the entire vaccine mixture within 4 hours after mixing. Any unused mixture or
waste material should be disposed according to the instructions given in section 5.5.