POM-V Prescription Required

Huvexxin 100 mg/ml Solution for Injection for Cattle, Pigs and Sheep

Active ingredient: Tulathromycin

Form

Injection

Species

Cattle Pigs Sheep

Manufacturer

Huvepharma N.V.

VMD MA No.

30282/5001

What it's used for

Cattle Treatment and metaphylaxis of bovine respiratory disease (BRD) associated with Mannheimia haemolytica, Histophilus somni and Mycoplasma bovis suscep...

Full indications, dosage and side effects ↓

View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Tulathromycin

1

Ask your vet for a written prescription

They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

Fill it at a registered online retailer

The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Your prescription rights → VMD register of retailers →

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Huvexxin 100 mg/ml Solution for Injection for Cattle, Pigs and Sheep — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 26 Mar 2026.

Cattle
Treatment and metaphylaxis of bovine respiratory disease (BRD)
associated with Mannheimia haemolytica,
Histophilus somni and Mycoplasma bovis susceptible to tulathromycin. The
presence of the disease in the group must be established before the
veterinary medicinal product is used.
Treatment of infectious bovine keratoconjunctivitis (IBK) associated with
Moraxella bovis susceptible to tulathromycin.
Pigs
Treatment and metaphylaxis of swine respiratory disease (SRD)
associated with Actinobacillus pleuropneumoniae, Pasteurella multocida,
Mycoplasma hyopneumoniae, Haemophilus parasuis and Bordetella
bronchiseptica susceptible to tulathromycin. The presence of the disease
in the group must be established before the veterinary medicinal product is
used. The veterinary medicinal product should only be used if pigs are

Revised: February 2024
AN: 00773/2023
expected to develop the disease within 2–3 days.
Sheep
Treatment of the early stages of infectious pododermatitis (foot rot)
associated with virulent Dichelobacter nodosus requiring systemic
treatment.

Do not use in cases of hypersensitivity to macrolide antibiotics or to any of
the excipients.

Cattle:
Very common
(>1 animal / 10 animals
treated):
Injection site pain
Injection site swelling
Injection site reactions
(e.g.congestion, oedema, fibrosis
and haemorrhage)
1
transient and can persist for up to 30 days
reversible and present for approximately 30 days after injection
Pigs:
Very common
(>1 animal / 10 animals
treated):
Injection site reactions (e.g.
congestion, oedema, fibrosis and
haemorrhage)
3
reversible and present for approximately 30 days after injection
Sheep:
Very common
(>1 animal / 10 animals
treated):
Discomfort (e.g.head shake –
behavioural disorder, injection site
scratching, anxiety)
4
these signs are transient and resolve within a few minutes

Revised: February 2024
AN: 00773/2023
Reporting adverse events is important. It allows continuous safety
monitoring of a veterinary medicinal product. Reports should be sent,
preferably via a veterinarian, to either the marketing authorisation holder or
its local representative or the national competent authority via the national
reporting system. See the package leaflet for respective contact details.

Cross resistance occurs with other macrolides. Do not administer
simultaneously with antimicrobials with a similar mode of action such as
other macrolides or lincosamides.
Sheep:
The efficacy of antimicrobial treatment of foot rot might be reduced by
other factors, such as wet environmental conditions, as well as
inappropriate farm management. Treatment of foot rot should therefore be
undertaken along with other flock management tools, for example
providing dry environment.
Antibiotic treatment of benign foot rot is not considered appropriate.
Tulathromycin showed limited efficacy in sheep with severe clinical signs
or chronic foot rot and should therefore only be given at an early stage of
foot rot.

Special precautions for use in animals
Use of the veterinary medicinal product should be based on susceptibility
testing of the bacteria isolated from the animal. If this is not possible,
therapy should be based on local (regional, farm level) epidemiological
information about susceptibility of the target bacteria.
Official, national and regional antimicrobial policies should be taken into
account when the veterinary medicinal product is used.
Use of the veterinary medicinal product deviating from the instructions
given in the SPC may increase the prevalence of bacteria resistant to
tulathromycin and may decrease the effectiveness of treatment with other
macrolides, lincosamides and group B streptogramins due to the potential
for cross resistance.
If a hypersensitivity reaction occurs appropriate treatment should be
administered without delay.
Special precautions to be take by the person administering the veterinary
medicinal product to animals
Tulathromycin is irritating to eyes. In case of accidental eye exposure, flush

Revised: February 2024
AN: 00773/2023
the eyes immediately with clean water.
Tulathromycin may cause sensitisation by skin contact resulting in e.g.
reddening of the skin (erythema) and/or dermatitis. In case of accidental
spillage onto skin, wash the skin immediately with soap and water.
Wash hands after use.
In case of accidental self-injection, seek medical advice immediately and
show the package leaflet or the label to the physician.
If there is suspicion of a hypersensitivity reaction following accidental
exposure (recognised by e.g. itching, difficulty in breathing, hives, swelling
on the face, nausea, vomitus) appropriate treatment should be
administered. Seek medical advice immediately and show the package
leaflet or the label to the physician.
Special precautions for the protection of the environment
Not applicable.
Other precautions
Not applicable.

interaction
None known.

This veterinary medicinal product does not require any special storage
conditions.

Meat and offal:
Cattle: 22 days.
Pigs: 13 days.
Sheep: 16 days.
Not authorised for use in animals producing milk for human consumption.
Do not use in pregnant animals, which are intended to produce milk for
human consumption, within 2 months of expected parturition.
5.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.