POM-V Prescription Required

Huvexxin 100 mg/ml Solution for Injection for Cattle, Pigs and Sheep

Active ingredient: Tulathromycin

Form

Injection

Species

Cattle Pigs Sheep

Manufacturer

Huvepharma N.V.

VMD MA No.

30282/3002

What it's used for

the group must be established before the veterinary medicinal product is used. Treatment of infectious bovine keratoconjunctivitis (IBK) associated with bo...

Full indications, dosage and side effects ↓

View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Tulathromycin

1

Ask your vet for a written prescription

They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

Fill it at a registered online retailer

The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Your prescription rights → VMD register of retailers →

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Huvexxin 100 mg/ml Solution for Injection for Cattle, Pigs and Sheep — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

the group must be established before the veterinary medicinal product is used.
Treatment of infectious bovine keratoconjunctivitis (IBK) associated with
bovis
Pigs
Treatment and metaphylaxis of swine respiratory disease (SRD) associated with
Actinobacillus pleuropneumoniae, Pasteurella multocida, Mycoplasma
hyopneumoniae, Haemophilus parasuis and susceptible
to tulathromycin. The presence of the disease in the group must be established
before the veterinary medicinal product is used. The veterinary medicinal product
should only be used if pigs are expected to develop the disease within 2–3 days.
Sheep
Treatment of the early stages of infectious pododermatitis (foot rot) associated
with virulent Dichelobacter nodosus

A single subcutaneous injection of 2.5 mg tulathromycin/kg bodyweight (equivalent
to 1 ml/40 kg bodyweight). For treatment of cattle over 300 kg bodyweight, divide
the dose so that no more than 7.5 ml are injected at one site.
Pigs
Intramuscular use.
A single intramuscular injection of 2.5 mg tulathromycin/kg bodyweight (equivalent
to 1 ml/40 kg bodyweight) in the neck.
For treatment of pigs over 80 kg bodyweight, divide the dose so that no more than
2 ml are injected at one site.
For any respiratory disease, it is recommended to treat animals in the early stages
of the disease and to evaluate the response to treatment within 48 hours after
injection. If clinical signs of respiratory disease persist or increase, or if relapse
occurs, treatment should be changed, using another antibiotic, and continued until
clinical signs have resolved.
Sheep
Intramuscular use.
A single intramuscular injection of 2.5 mg tulathromycin/kg body weight (equivalent
to 1 ml/40 kg body weight) in the neck.
To ensure a correct dosage, bodyweight should be determined as accurately as
possible. The closure may be safely punctured 15 times. In order to prevent
excessive broaching of the stopper, a suitable multiple dosing device should be
used.

Do not use in cases of hypersensitivity to macrolide antibiotics or to any of the
excipients.

Cattle:
Very common
(>1 animal / 10 animals
treated):
Injection site pain
Injection site swelling
Injection site reactions (e.g. congestion,
oedema, fibrosis and haemorrhage)
1
transient and can persist for up to 30 days
reversible and present for approximately 30 days after injection
Pigs:
Very common
(>1 animal / 10 animals
treated):
Injection site reactions (e.g. congestion,
oedema, fibrosis and haemorrhage)
3
reversible and present for approximately 30 days after injection
Sheep:
Very common
(>1 animal / 10 animals
treated):
Discomfort (e.g. head shake – behavioural
disorder, injection site scratching, anxiety)
4
these signs are transient and resolve within a few minutes
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian,
to either the marketing authorisation holder or its local representative or the
national competent authority via the national reporting system. See the package
leaflet for respective contact details.

Cross resistance occurs with other macrolides. Do not administer simultaneously
with antimicrobials with a similar mode of action such as other macrolides or
lincosamides.
Sheep:
The efficacy of antimicrobial treatment of foot rot might be reduced by other
factors, such as wet environmental conditions, as well as inappropriate farm
management. Treatment of foot rot should therefore be undertaken along with
other flock management tools, for example providing dry environment.
Antibiotic treatment of benign foot rot is not considered appropriate. Tulathromycin
showed limited efficacy in sheep with severe clinical signs or chronic foot rot and
should therefore only be given at an early stage of foot rot.

Special precautions for safe use in the target species:
Use of the veterinary medicinal product should be based on susceptibility testing
of the bacteria isolated from the animal. If this is not possible, therapy should be
based on local (regional, farm level) epidemiological information about
susceptibility of the target bacteria.
Official, national and regional antimicrobial policies should be taken into account
when the veterinary medicinal product is used.
Use of the veterinary medicinal product deviating from the instructions given in the
SPC may increase the prevalence of bacteria resistant to tulathromycin and may
decrease the effectiveness of treatment with other macrolides, lincosamides and
group B streptogramins due to the potential for cross resistance.
If a hypersensitivity reaction occurs appropriate treatment should be administered
without delay.
Special precautions to be taken by the person administering the veterinary
medicinal product to animals:
Tulathromycin is irritating to eyes. In case of accidental eye exposure, flush the
eyes immediately with clean water.
Tulathromycin may cause sensitisation by skin contact resulting in e.g. reddening
of the skin (erythema) and/or dermatitis. In case of accidental spillage onto skin,
wash the skin immediately with soap and water.
Wash hands after use.
In case of accidental self-injection, seek medical advice immediately and show the
package leaflet or the label to the physician.
If there is suspicion of a hypersensitivity reaction following accidental exposure
(recognised by e.g. itching, difficulty in breathing, hives, swelling on the face,
nausea, vomitus) appropriate treatment should be administered. Seek medical
advice immediately and show the package leaflet or the label to the physician.
Special precautions for the protection of the environment:
Not applicable.

None known.

This veterinary medicinal product does not require any special storage conditions.

Meat and offal:
Cattle: 22 days.
Pigs: 13 days.
Sheep: 16 days.
Not authorised for use in animals producing milk for human consumption.
Do not use in pregnant animals, which are intended to produce milk for human
consumption, within 2 months of expected parturition.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.