POM-V Prescription Required

Fencovis Suspension for Injection

Active ingredients: Bovine coronavirus, Bovine rotavirus, Escherichia coli

Form

Injection

Species

Cattle

Manufacturer

Boehringer Ingelheim Vetmedica GmbH

VMD MA No.

04491/3000

What it's used for

(K99) adhesin and to increase the level of passive immunity of calves against neonatal diarrhoea caused by bovine rotavirus, bovine coronavirus and E. coli...

Full indications, dosage and side effects ↓

View official SPC (PDF)

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Clinical information

Fencovis Suspension for Injection — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

(K99) adhesin and to increase the level of passive immunity of calves against neonatal
diarrhoea caused by bovine rotavirus, bovine coronavirus and E. coli expressing F5 (K99)
adhesin.
In calves fed with colostrum and milk from vaccinated cows for the first week of life,
laboratory studies conducted with heterologous challenge strains (a G6 BRV strain, a
BCV strain and a K99 E. coli strain) have demonstrated that these antibodies:
-E. coli expressing F5
(K99) adhesin,
-
coronavirus,
-
coronavirus.
Onset of immunity:
In calves fed with colostrum from vaccinated heifers or cows, passive immunity
commences with colostrum feeding and is dependent on calves receiving sufficient
colostrum after birth.
Duration of immunity:
Calves fed with colostrum and milk from vaccinated dams for the first week of life are
protected against bovine rotavirus for 7 days and against bovine coronavirus for 14 days.
The duration of immunity against infections caused by E. coli expressing F5 (K99)
adhesin was not studied since such disease is usually observed in calves less than 3
days of age and susceptibility to enterotoxigenic E. coli is age dependent.

Slowly warm up to room temperature and gently shake the content of the vial before
administration.
Administration:
One dose of 2 ml by intramuscular injection.
A single injection should be given during each pregnancy between 12 and 3 weeks
before the expected calving.
Colostrum feeding:
Calves are born without protection from antibodies. Immunity against calf diarrhoea is
provided by rapid uptake of colostral antibodies from vaccinated dams. The first
colostrum intake should take place as soon as possible, ideally within 2 hours and at
most 6 hours after birth. In dairy calves, it should represent a volume equivalent to
approximately 10% of the body weight, followed by a similar volume within 12 hours. Beef
calves should stand and suckle within 2 hours of calving.

None.

Cattle (pregnant heifers and cows).
Very common
(>1 animal / 10 animals treated):
Elevated temperature
.Common
(1 to 10 animals / 100 animals
treated):
Injection site swelling
.
Mean increase of 1.0 °C that may reach 2.1 °C in individual cases, resolving within 2
days.
Localised (diameter 5 cm), mild, resolving within 2 days.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or the national competent authority via the
national reporting system. See the package leaflet for respective contact details.

Vaccinate healthy animals only.

Special precautions for safe use in the target species:
To achieve optimum results and to reduce infection pressure on the farm, a whole herd
cow vaccination policy should be adopted, as well as standard infectious diseases control
practices.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals:
In case of adverse reactions following accidental self-injection, seek medical advice
immediately and show the package leaflet or the label to the physician.
Special precautions for the protection of the environment:
Not applicable.

No information is available on the safety and efficacy of this vaccine when used with any
other immunological veterinary medicinal product. A decision to use this vaccine before
or after any other immunological veterinary medicinal product therefore needs to be
made on a case-by-case basis.

Store and transport refrigerated (2 °C – 8 °C).
Once open, the vials should not be stored above 25 °C.
Do not freeze.
Protect from light.

Zero days.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.