POM-V Prescription Required

Equibactin Vet. (333 mg/g + 67 mg/g) Oral Paste for Horses

Active ingredients: Sulfadiazine, Trimethoprim

Form

Paste

Species

Horses

Manufacturer

Le Vet B.V.

VMD MA No.

19994/4004

What it's used for

aureus; Gastrointestinal infections associated with E. coli; Urogenital infections associated with beta-hemolytic streptococci; Wound infections and open o...

Full indications, dosage and side effects ↓

View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Sulfadiazine + Trimethoprim

1

Ask your vet for a written prescription

They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

Fill it at a registered online retailer

The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

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Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Equibactin Vet. (333 mg/g + 67 mg/g) Oral Paste for Horses — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

aureus;
Gastrointestinal infections associated with E. coli;
Urogenital infections associated with beta-hemolytic streptococci;
Wound infections and open or drained abscesses associated with
spp. and Staphylococcus aureus.

Posology:
5 mg trimethoprim and 25 mg sulfadiazine per kg body weight per day to a maximum
of 5 days.
One syringe is intended for 600 kg body weight and each syringe is subdivided into
12 markings.
The equivalent of one marking is sufficient to treat 50 kg of body weight and the
minimum body weight for treatment is 50 kg.
Directions for use:
To ensure a correct dosage, body weight should be determined as accurately as
possible.
The calculated dose is provided by adjusting the ring on the plunger according to the
body weight of the horse.
The paste is administered orally by inserting the nozzle of the syringe through the
interdental space and depositing the required amount of paste on the back of the
tongue. The animal's mouth should be free of any food. Immediately after
administration, elevate the head of the horse for a few seconds to ensure the dose is
swallowed.

Do not use in cases of hypersensitivity to sulfonamides.
AN: 00081/2025 & 00082/2025
Do not use in animals with serious hepatic or renal insufficiency or with blood
dyscrasias.
Do not use in case resistance to sulphonamides occurs.
Do not use to treat abscesses without proper drainage.

Horses:
Very rare
(<1 animal / 10 000 animals
treated, including isolated
reports):
Decreased appetite, appetite loss
Loose stool, diarrhoea
Undetermined frequency
(cannot be estimated from the
available data):
Haematuria, crystalluria
Renal tubular disorder
1
Tubular obstruction.
AN: 00081/2025 & 00082/2025
If such effects appear, discontinue treatment immediately and institute appropriate
symptomatic measures.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or its local representative or the national
competent authority via the national reporting system. See the package leaflet for
respective contact details.

None.

Special precautions for safe use in the target species:
During treatment with the veterinary medicinal product animals must have free and
easy access to drinking water.
Do not use the same syringe in more than one animal.
Use of the product should be based on susceptibility testing and take into account
official and local antimicrobial policies.
Use of the veterinary medicinal product deviating from the instructions given in the
SPC may increase the prevalence of bacteria resistant to the combination of
sulfadiazine and trimethoprim, and may decrease the effectiveness of treatment with
sulphonamides and/or trimethoprim due to the potential for cross-resistance.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals:
People with known hypersensitivity to sulfonamides should avoid contact with the
veterinary medicinal product.
In case of hypersensitivity-type reactions after exposure (such as skin rash), seek
medical advice and show the package leaflet or the label to the physician.
In case of severe reactions (swelling of the face, lips or eyes), seek prompt medical
attention and take the package leaflet with you.
Special precautions for the protection of the environment:
Not applicable.

Potentiated sulfonamides used in conjunction with detomidine are known to be able
to cause fatal arrhythmias in the horse.

Do not refrigerate or freeze.

Meat and offal: 14 days.
Not authorised for use in animals producing milk for human consumption.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.