Endofluke 100 mg/ml Oral Suspension

Care should be taken to avoid the following practices, because they increase the risk of
development of resistance and could ultimately result in ineffective therapy:
- Too frequent and repeated use of anthelmintics from the same class, over an
extended period of time.
-
misadministration of the veterinary medicinal product or lack of calibration of the
dosing device (if any).
Suspected clinical cases of resistance to anthelmintics should be further investigated
using appropriate tests (e.g. Faecal Egg Count Reduction Test). Where the results of
the test(s) strongly suggest resistance to a particular anthelmintic, an anthelmintic
belonging to another pharmacological class and having a different mode of action
should be used.
Resistance to triclabendazole has been reported in Fasciola hepatica in cattle and
sheep. Therefore, the use of this veterinary medicinal product should be based on
local (regional/farm) epidemiological information about susceptibility of the Fasciola
hepatica and recommendations on how to limit further selection for resistance to
anthelmintics.

Special precautions for safe use in the target species:
Care should be taken when dosing animals to avoid causing injury to the mouth and
pharynx.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals
When using, do not eat, drink or smoke.
Wash splashes from eyes and skin immediately.
Take off immediately any contaminated clothing.
Wash hands and exposed skin before meals and after use.
Special precautions for the protection of the environment:
The use of this veterinary medicinal product may have harmful effects on fish and
aquatic invertebrates. Cattle and sheep must not have any access to the surface water
such as streams, ponds or ditches within 7 days after treatment. When spreading
manure from treated animals on arable lands, a safety distance of 10 metres to
adjacent surface waters must be kept.
AN: 01240/2024 & 01241/2024