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POM-V Prescription Required Companion Animal

Efex 40 mg Chewable Tablets for Dogs

Active ingredient: Marbofloxacin

Form

Chewable

Species

Dogs

Manufacturer

Ceva Sante Animale

VMD MA No.

14966/3035

What it's used for

- urinary tract infections (UTI) associated or not with prostatitis or epididymitis. - respiratory tract infections.

Full indications, dosage and side effects ↓
View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Marbofloxacin

  1. 1

    Ask your vet for a written prescription

    They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.

  2. 2

    Fill it at a registered online retailer

    The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Efex 40 mg Chewable Tablets for Dogs — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

- urinary tract infections (UTI) associated or not with prostatitis or epididymitis.
- respiratory tract infections.
Dogs:
- in skin and soft tissue infections, treatment duration is at least 5 days. Depending
on the course of the disease, it may be extended up to 40 days.
- in urinary tract infections, treatment duration is at least 10 days. Depending on the
course of the disease, it may be extended up to 28 days.
- in respiratory infections, treatment duration is at least 7 days and depending on the
course of the disease, it may be extended up to 21 days.
To ensure a correct dosage body weight should be determined as accurately as
possible.
The chewable tablets may be accepted by dogs or can be administered directly
into the mouth of the animals.
Instruction on how to divide the tablet: Put the tablet on an even surface, with its
scored side facing down (convex face up). With the tip of the forefinger, exert slight
vertical pressure on the middle of the tablet to break it along its width into halves.
Then, in order to obtain quarters, exert slight pressure on the middle of one half with
the forefinger to break it into two parts.
Do not use in dogs aged less than 12 months, or less than 18 months for giant
breeds of dogs with a longer growth period.
AN: 01804/2025Page 2 of 6
Do not use in cases of hypersensitivity to the active substance, other
(fluoro)quinolones or any of the excipients.
Dogs:
Very rare
(<1 animal / 10,000 animals
treated, including isolated
reports ):
Vomiting
, Soft stool
Hyperactivity
1,2
Modification of thirst
1
Transient
Cease spontaneously after treatment
AN: 01804/2025Page 3 of 6
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or the national competent authority via the
national reporting system. See the package leaflet for respective contact details.
A low urinary pH could have an inhibitory effect on the activity of marbofloxacin.

Special precautions for safe use in the target species:
The chewable tablets are flavoured. In order to avoid any accidental ingestion, store
tablets out of reach of the animals.
The fluoroquinolones have been shown to induce erosion of articular cartilage in
juvenile dogs and care should be taken to dose accurately especially in young
animals.
The fluoroquinolones are also known for their potential neurological side effects.
Cautious use is recommended in dogs and cats diagnosed as suffering from
epilepsy.
Fluoroquinolones should be reserved for the treatment of clinical conditions which
have responded poorly, or are expected to respond poorly to other classes of
antimicrobials. Whenever possible, use of fluoroquinolones should be based on
susceptibility testing. Use of the product deviating from the instructions given in the
SPC may increase the prevalence of bacteria resistant to the fluoroquinolones and
may decrease effectiveness of treatment with other quinolones due to the potential
for cross-resistance.
Official and local antimicrobial policies should be taken into account when the product
is used.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals
People with known hypersensitivity to (fluoro)quinolones or other components of the
formulation should avoid contact with the veterinary medicinal product. In case of
accidental ingestion seek medical advice immediately and show the package leaflet
or the label to the physician. Wash hands after use.
Special precautions for the protection of the environment:
Not applicable.
Fluoroquinolones are known to interact with orally administered cations (Aluminium,
Calcium, Magnesium, Iron). In such cases, the bioavailability may be reduced.
Serum levels of theophylline should be carefully monitored when theophylline and
marbofloxacin are used concomitantly, as fluoroquinolones may increase serum levels
of theophylline.
Blister: PVC-TE-PVDC – aluminium heat sealed: Do not store above 30°C.
Blister: PA-AL-PVC – aluminium heat sealed: This veterinary medicinal product does
not require any special temperature storage conditions.
Tablet portions should be stored in the blister pack.
Any tablet portions remaining after 72 hours should be discarded.
Keep the blister in the outer carton.
Not applicable.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.

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