POM-V Prescription Required

Coxevac Suspension for Injection for Cattle, Goats and Sheep

Active ingredient: Coxiella burnetii

Form

Injection

Species

Cattle Goats Sheep

Manufacturer

Ceva Sante Animale

VMD MA No.

EU/2/10/110/001-002

What it's used for

Cattle: For the active immunisation of cattle to lower the risk for non-infected animals vaccinated when nonpregnant to become shedder (5 times lower proba...

Full indications, dosage and side effects ↓

View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Coxiella burnetii

1

Ask your vet for a written prescription

They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

Fill it at a registered online retailer

The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Your prescription rights → VMD register of retailers →

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Coxevac Suspension for Injection for Cattle, Goats and Sheep — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

Cattle:
For the active immunisation of cattle to lower the risk for non-infected animals
vaccinated when nonpregnant to become shedder (5 times lower probability in
comparison with animals receiving a placebo), and to reduce shedding of Coxiella
burnetii in these animals via milk and vaginal mucus.
Onset of immunity: not established.
Duration of immunity: 280 days after completion of the primary vaccination course.
Goats:

Revised: December 2024
AN: 02877/2023
Page 2 of 7For the active immunisation of goats to reduce abortion caused by Coxiella burnetii
and to reduce shedding of the organism via milk, vaginal mucus, faeces and
placenta.
Onset of immunity: not established.
Duration of immunity: one year after completion of the primary vaccination course.
Sheep:
For the active immunisation of sheep against Coxiella burnetii to reduce shedding of
the organism via milk, vaginal mucus and faeces.
Onset of immunity: not established
Duration of immunity: 4 months

None.

Revised: December 2024
AN: 02877/2023
Cattle:
Very common
(>1 animal / 10 animals
treated):
Injection site swelling* Rare
(1 to 10 animals / 10,000
animals treated):
Lethargy, Hyperthermia, Anorexia
* Palpable, of 9 to 10 cm diameter maximum, which may last for 17 days, reduces
gradually and disappears without need for treatment.
Goats:
Very common
(>1 animal / 10 animals
treated):
Injection site swelling*
Hyperthermia**
Uncommon
(1 to 10 animals / 1,000
animals treated):
Lethargy, Malaise, AnorexiaRare
(1 to 10 animals / 10,000
animals treated):
Diarrhoea
* Palpable, of 3 to 4 cm diameter maximum, which may last for 14 days, reduces and
disappears without need for treatment.
** For 4 days post-vaccination.
Sheep:
Very common
(>1 animal / 10 animals
treated):
Injection site inflammation, application site
thickening*
Rare
(1 to 10 animals / 10,000
animals treated)
Lethargy, Hyperthermia**, Anorexia
* Palpable, of 5 cm diameter maximum, which may last for 14 days, reduces and
disappears without need for treatment. Reactions are expected to be more severe
after the second injection.
** 2.5°C increase maximum, not lasting more than one day.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or the national competent authority via the
national reporting system. See also section 16 of the package leaflet for contact
details.

Vaccination of animals already infected at the time of vaccination will have no
adverse effect.
No efficacy data are available concerning the use of COXEVAC in male animals.
However, in safety laboratory trials, the use of COXEVAC in males proved to be safe.
In the case that it is decided to vaccinate the whole herd, it is advisable to vaccinate
the male animals at the same time.
There are no benefits of the vaccine (as described in the indications for cattle), when
used in infected and/or pregnant cows.
The biological significance of the levels of reduction shown in shedding in cattle and
goats is not known.

i) Special precautions for use in animals
It is advisable to vaccinate all the animals in the herd at the same time.
Under field conditions, vaccination with COXEVAC has commonly been followed by a
decrease in milk production in goats. Since stress could contribute to this adverse
reaction, appropriate precautions should be taken to reduce stress as much as
possible during the administration of the product.
ii) Special precautions to be taken by the person administering the veterinary
medicinal product to animals
In case of accidental self-injection, seek medical advice immediately and show the
package leaflet or the label to the physician.
iii) Other precautions
None

No information is available on the safety and efficacy of this vaccine when used with
any other veterinary medicinal product. A decision to use this vaccine before or after
any other veterinary medicinal product therefore needs to be made on a case-by-
case basis.

Store and transport refrigerated (2 ºC − 8 ºC). Do not freeze.
Keep the vial in the outer carton in order to protect from light.

Meat, milk and offal: Zero days.
5. IMMUNOLOGICAL PROPERTIES
Pharmacotherapeutic group: immunologicals for bovidae, inactivated bacterial
vaccines for cattle.
ATC Vet Code: QI02AB.
The vaccine contains phase I Coxiella burne
immunity against Q fever in cattle, goats and sheep.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.