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POM-VPS Prescription Required

Cocci-Drench 2.5 mg/ml Oral Suspension

Active ingredient: Diclazuril

Form

Liquid

Species

Cattle Sheep

Manufacturer

Intervet International B.V.

VMD MA No.

06376/3038

What it's used for

To aid in the control of coccidiosis in calves caused by Eimeria bovis and

Full indications, dosage and side effects ↓
View official SPC (PDF)

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Clinical information

Cocci-Drench 2.5 mg/ml Oral Suspension — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

To aid in the control of coccidiosis in calves caused by Eimeria bovis and
To ensure a correct dosage, bodyweight should be determined as accurately as possible.
Lambs:
Therapeutic use: 1 mg diclazuril per kg bodyweight or 1 ml of the veterinary medicinal
product per 2.5 kg bodyweight, as a single administration.
Preventative use: 1 mg diclazuril per kg bodyweight or 1 ml of the veterinary medicinal
product per 2.5 kg bodyweight at about 4 - 6 weeks of age at the time that coccidiosis can
normally be expected on the farm.
Under conditions of high infection pressure, a second treatment may be indicated about 3
weeks after the first dosing.
Calves:
To aid in the control of coccidiosis: 1 mg diclazuril per kg bodyweight or 1 ml of the
veterinary medicinal product per 2.5 kg bodyweight, administered as a single dose, 14
days after moving into a potentially high-risk environment.
If a satisfactory response is not observed, then further advice should be sought from your
veterinary surgeon and the cause of the condition should be reviewed. It is good practice
to ensure the cleanliness of calf housing.
Treatment with diclazuril causes interruption of the coccidial cycle and of excretion of
oocysts for approximately 2 to 3 weeks after administration.
Method of administration
Shake well before use.
After using the draw-off cap, re-close the container with the original cap. The veterinary
medicinal product should be administered with a drenching gun. Appropriate drenching
equipment should be used to allow accurate dosing. This is particularly important when
administering small volumes.
None.
Sheep (lambs) and cattle (calves):
Very rare
(<1 animal / 10,000 animals
treated, including isolated reports):
Gastrointestinal signs (e.g. Diarrhoea
1,2
);
Lethargy, Recumbency;
Agitation;
Neurological signs (e.g. Paresis).
with possible presence of blood.
in some treated animals, even though oocyst excretion is reduced to a very low level.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or its local representative or the national
competent authority via the national reporting system. See the package leaflet for
respective contact details.
None.

Special precautions for safe use in the target species:
For oral use only.
It is advocated to treat all lambs of the flock and all calves in a pen. This will contribute to
reduce the infection pressure and assure a better epidemiological control of the
coccidiosis infection.
Lambs
On rare occasions, in highly susceptible lambs e.g. where they have been housed for long
periods of time before being turned out onto heavily contaminated pasture, a severe scour
has been seen shortly after dosing. In such cases, fluid therapy is essential and the use of
a sulphonamide should be considered. It is also important to consider other potential
pathogens that may be playing a role e.g. Cryptosporidium, Nematodirus, Rotavirus,
GiardiaE. .
In the event of any stress factors (e.g. cold weather, other diseases) or high challenge
(e.g. warm wet weather, inability to move lambs from infected pastures after dosing) the
timing of the doses may need to be adjusted.
Calves
Clinical coccidiosis generally occurs late in the parasite’s life cycle after most of the
damage to the calf’s intestine has already been done. This severely damaged intestine
can easily be infected by secondary bacteria and/or other agents. In cases of acute clinical
coccidiosis treated with the veterinary medicinal product, fluid therapy is essential and the
use of an antibiotic should be considered. Symptoms of clinical disease may remain
obvious in some calves treated with the veterinary medicinal product, even though oocyst
excretion is reduced to a very low level, and overall prevalence of diarrhoea is decreased.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals:
Wash hands after use.
Special precautions for the protection of the environment:
Not applicable.
None known.
Do not store above 30 °C.
Protect from frost.
Lambs and calves:
Meat and offal: Zero days.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.

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