Clavaseptin 750 mg Palatable Tablets for Dogs
Active ingredients: Amoxicillin, Clavulanic Acid
Form
Tablet
Species
Manufacturer
Vetoquinol UK Limited
VMD MA No.
08007/5010
What it's used for
In dogs: treatment or adjunctive treatment of periodontal infections caused by bacteria susceptible to amoxicillin in combination with clavulanic acid i.e....
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Prescription required
Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.
Clavaseptin 750 mg Palatable Tablets for Dogs — SPC Details
Source: VMD Summary of Product Characteristics (SPC). Last updated 18 Mar 2026.
susceptible to amoxicillin in combination with clavulanic acid i.e.
Streptococcus spp and Escherichia coli.
To ensure the correct dosage, body weight should be determined as accurately as
possible to avoid under-dosing.
The recommended dose of the product is 10 mg amoxicillin / 2.5 mg clavulanic acid
per kg body weight twice a day by the oral route in dogs, i.e. 1 tablet per 60 kg body
weight every 12 h, according to the following table:
Bodyweight (kg)Number of tablets twice daily[ >20 - 30 ]½[ 30.1 - 45 ]3/4[ 45.1 - 60 ]1[60.1 - 75]1 ¼[75.1 - 90]1 ½
In severe periodontal infections the dose may be doubled to 20 mg amoxicillin / 5 mg
clavulanic acid/kg body weight twice daily.
Issued: May 2022
AN: 01361/2020
Duration of treatment:
- 7 days for the treatment of periodontal infections in dogs.
β-lactam
Do not administer to gerbils, guinea pigs, hamsters, rabbits and chinchillas.
Do not administer to horses and ruminating animals.
Do not use in animals with serious dysfunction of the kidneys accompanied by anuria
or oliguria.
Do not use in cases of known resistance to the combination of amoxicillin and
clavulanic acid.
Issued: May 2022
AN: 01361/2020
depending on the severity of the undesirable effects and a benefit/risk evaluation by
the veterinary surgeon.
Hypersensitivity reactions (allergic skin reactions, anaphylaxis) may be observed very
rarely. In these cases, administration should be discontinued and a symptomatic
treatment given.
The frequency of adverse reactions is defined using the following convention:
- very common (more than 1 in 10 animals treated displaying adverse reaction(s))
- common (more than 1 but less than 10 animals in 100 animals treated)
- uncommon (more than 1 but less than 10 animals in 1,000 animals treated)
- rare (more than 1 but less than 10 animals in 10,000 animals treated)
- very rare (less than 1 animal in 10,000 animals treated, including isolated reports).
Special precautions for use in animals
In animals with impaired liver and kidney function, the use of the product should be
subject to a benefit/risk evaluation by the veterinary surgeon and the posology
evaluated carefully.
Caution is advised in the use in small herbivores other than those in 4.3.
Use of the product should be based on susceptibility testing.
Use of the product should be in accordance with official, national and regional
antimicrobial policies.
Use of the product deviating from the instructions given in the SPC may increase the
prevalence of bacteria resistant to amoxicillin/clavulanic acid and may decrease the
effectiveness of treatment with other -lactam antibiotics, due to the potential for cross
resistance.
Narrow spectrum antibacterial therapy with a lower risk of antimicrobial resistance
selection should be used for first line treatment where susceptibility testing suggests
the likely efficacy of this approach.
Do not use in cases of bacteria sensitive to narrow spectrum penicillins or to amoxicillin
as a single substance.
The tablets are flavoured. In order to avoid any accidental ingestion, store tablets out
of reach of the animals.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals
Penicillins and cephalosporins may cause hypersensitivity (allergy) following injection,
inhalation, ingestion or skin contact. Hypersensitivity to penicillins may lead to cross
reactions to cephalosporins and . Allergic reactions to these substances
may occasionally be serious.
Do not handle this product if you know you are sensitised, or if you have been advised
not to work with such preparations.
Handle this product with great care to avoid exposure, taking all recommended
precautions.
If you develop symptoms following exposure, such as skin rash, you should seek
medical advice and show the doctor this warning.
Swelling of the face, lips or eyes or difficulty breathing are more serious symptoms and
require urgent medical attention.
Wash hands after handling the tablets.
Accidental ingestion of the product by a child may be harmful. To avoid accidental
ingestion, particularly by a child, unused part-tablets should be returned to the open
blister space and inserted back into the carton.
In case of accidental ingestion, seek medical advice and show the package leaflet or
the label to the physician.
Issued: May 2022
AN: 01361/2020
bacteriostatic substances such as macrolides, tetracyclines, sulfonamides and
chloramphenicol.
The potential for allergic cross-reactivity with other penicillins should be considered.
Penicillins may increase the effect of aminoglycosides.
Return any part of tablet to the opened blister- and use within 48 hours.
clavulanic acid/kg body weight twice daily.
Issued: May 2022
AN: 01361/2020
Duration of treatment:
- 7 days for the treatment of periodontal infections in dogs.
4.10 Overdose (symptoms, emergency procedures, antidotes), if necessary
At three times the recommended dose for a period of 28 days, diarrhoea was observed
in dogs. In the event of an overdose symptomatic treatment is advised.
4.11 Withdrawal period(s)
Not applicable
5.
This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.
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