POM-V Prescription Required Companion Animal

Clavaseptin 62.5 mg Palatable Tablets for Dogs and Cats

Active ingredients: Amoxicillin, Clavulanic Acid

Form

Tablet

Species

Cats Dogs

Manufacturer

Vetoquinol UK Limited

VMD MA No.

08007/5009

What it's used for

In dogs: treatment or adjunctive treatment of periodontal infections caused by bacteria susceptible to amoxicillin in combination with clavulanic acid i.e....

Full indications, dosage and side effects ↓

View official SPC (PDF)

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1

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2

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Prescription required

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Clinical information

Clavaseptin 62.5 mg Palatable Tablets for Dogs and Cats — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 18 Mar 2026.

In dogs: treatment or adjunctive treatment of periodontal infections caused by
bacteria susceptible to amoxicillin in combination with clavulanic acid i.e.
spp, Streptococcus spp and Escherichia coli.
In cats: treatment of skin infections (including wounds and abscesses) caused by
bacteria susceptible to amoxicillin in combination with clavulanic acid i.e.
spp, Staphylococcus spp, Streptococcus spp and

For oral administration.
To ensure the correct dosage, body weight should be determined as accurately as
possible to avoid under-dosing.
The recommended dose of the product is 10 mg amoxicillin /2.5 mg clavulanic acid
per kg body weight twice a day by the oral route in dogs and cats, i.e. 1 tablet per 5
kg body weight every 12 h, according to the following table:
Bodyweight (kg)Number of tablets twice daily[ 1.0- 2.5 ]½[ 2.6- 5.0 ]1[ 5.1- 7.5 ]1 ½[ 7.6- 10.0 ]2
In severe infections in each target species, the dose may be doubled to 20 mg
amoxicillin/5 mg clavulanic acid/kg body weight twice daily.
Duration of treatment:
- 7 days for the treatment of periodontal infections in dogs.
- 7 days for the treatment of skin infections in cats (including wounds and
abscesses). The clinical status of animals should be re-evaluated after 7 days and
the treatment prolonged for a further 7 days if necessary. Severe cases of skin
infection may require an even longer duration of treatment and this should be at the
discretion of the responsible veterinarian.

Do not use in cases of hypersensitivity to penicillins or other substances of the
lactam group or to any of the excipients.
Do not administer to gerbils, guinea pigs, hamsters, rabbits and chinchillas.
Do not administer to horses and ruminating animals.

Revised: February 2020
AN: 00191/2019
Do not use in animals with serious dysfunction of the kidneys accompanied by anuria
or oliguria.
Do not use in cases of known resistance to the combination of amoxicillin and
clavulanic acid.

Vomiting and diarrhoea may be observed very rarely. Treatment may be discontinued
depending on the severity of the undesirable effects and a benefit/risk evaluation by
the veterinary surgeon.
Hypersensitivity reactions (allergic skin reactions, anaphylaxis) may be observed very
rarely. In these cases, administration should be discontinued and a symptomatic
treatment given.

Revised: February 2020
AN: 00191/2019
The frequency of adverse reactions is defined using the following convention:
- very common (more than 1 in 10 animals treated displaying adverse reaction(s))
- common (more than 1 but less than 10 animals in 100 animals treated)
- uncommon (more than 1 but less than 10 animals in 1,000 animals treated)
- rare (more than 1 but less than 10 animals in 10,000 animals treated)
- very rare (less than 1 animal in 10,000 animals treated, including isolated reports).

None

Special precautions for use in animals
In animals with impaired liver and kidney function, the use of the product should be
subject to a risk/benefit evaluation by the veterinary surgeon and the posology
evaluated carefully.
Caution is advised in the use in small herbivores other than those in 4.3.
Use of the product should be based on susceptibility testing.
Use of the product deviating from the instructions given in the SPC may increase the
prevalence of bacteria resistant to amoxicillin/clavulanic acid may decrease the
effectiveness of treatment with other antibiotics, due to the potential for
cross resistance. Use of the product should take into account official and local
antimicrobial policies. Do not use in cases of bacteria sensitive to narrow spectrum
penicillins or to amoxicillin as a single substance.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals
Penicillins and cephalosporins may cause hypersensitivity (allergy) following
injection, inhalation, ingestion or skin contact. Hypersensitivity to penicillins may lead
to cross reactions to cephalosporins and
substances may occasionally be serious.
1. Do not handle this product if you know you are sensitised, or if you have been
advised not to work with such preparations.
2. Handle this product with great care to avoid exposure, taking all recommended
precautions.
3. If you develop symptoms following exposure, such as skin rash, you should
seek medical advice and show the doctor this warning.
Swelling of the face, lips or eyes or difficulty breathing are more serious symptoms
and require urgent medical attention.
Wash hands after handling the tablets.

The bactericidal activity of amoxicillin may be reduced by the simultaneous use of
bacteriostatic substances such as macrolides, tetracyclines, sulfonamides and
chloramphenicol.
The potential for allergic cross-reactivity with other penicillins should be considered.
Penicillins may increase the effect of aminoglycosides.

Do not store above 25°C. Store in the original package.
Return any halved tablet to the opened blister-pack and use within 16 hours.

In severe infections in each target species, the dose may be doubled to 20 mg
amoxicillin/5 mg clavulanic acid/kg body weight twice daily.
Duration of treatment:
- 7 days for the treatment of periodontal infections in dogs.
- 7 days for the treatment of skin infections in cats (including wounds and
abscesses). The clinical status of animals should be re-evaluated after 7 days and
the treatment prolonged for a further 7 days if necessary. Severe cases of skin
infection may require an even longer duration of treatment and this should be at the
discretion of the responsible veterinarian.
4.10 Overdose (symptoms, emergency procedures, antidotes), if necessary

Revised: February 2020
AN: 00191/2019
At three times the recommended dose for a period of 28 days, a decrease in
cholesterol values and episodes of vomiting were observed in cats and diarrhoea
was observed in dogs. In the event of an overdose symptomatic treatment is advised.
4.11 Withdrawal period(s)
Not applicable
5.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.