POM-V Prescription Required Companion Animal

Clavaseptin 62.5 mg Palatable Tablets for Dogs and Cats

Active ingredients: Amoxicillin, Clavulanic Acid

Form

Tablet

Species

Cats Dogs

Manufacturer

Vetoquinol SA

VMD MA No.

06462/3003

What it's used for

• caused by spp and E. coli. • spp, and Pasteurella spp. •, Proteus mirabilis. •E. coli. In cats: treatment of infections caused by bacteria susceptible to...

Full indications, dosage and side effects ↓

View official SPC (PDF)

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Prescription required

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Clinical information

Clavaseptin 62.5 mg Palatable Tablets for Dogs and Cats — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

•
caused by spp and E. coli.
• spp,
and Pasteurella spp.
•,
Proteus mirabilis.
•E. coli.
In cats: treatment of infections caused by bacteria susceptible to amoxicillin in
combination with clavulanic acid (including beta-lactamase producing strains), in
particular:
•
caused by spp, Streptococcus spp and Pasteurella spp.
•
caused by spp and E. coli.
• spp,
and Pasteurella spp.
•, spp,
Klebsiella spp and Proteus mirabilis.
•E. coli.

To ensure the correct dosage, body weight should be determined as accurately as
possible.
The recommended dose of the veterinary medicinal product is 10 mg amoxicillin
/2.5 mg clavulanic acid per kg body weight twice a day, i.e. 1 tablet per 5 kg body
weight every 12 h, for 5 to 7 days, according to the following table:
Bodyweight (kg)Number of tablets twice daily[ 1.0 - 2.5 ]½[ 2.6 - 5.0 ]1[ 5.1 - 7.5 ]1 ½[ 7.6 - 10.0 ]2
In severe cases, the dose can be doubled at the discretion of the responsible
veterinarian.
Duration of the treatment:
For all indications, a treatment of 5 to 7 days is sufficient in the majority of cases.
For chronic or recurrent cases, it may be necessary to continue treatment for
2 to 4 weeks.

Do not use in cases of hypersensitivity to penicillins or other substances of the
lactam group or to any of the excipients.
Do not administer to gerbils, guinea pigs, hamsters, rabbits and chinchillas or other
small herbivores.
Do not use in animals with serious dysfunction of the kidneys accompanied by anuria
or oliguria.
Do not administer to horses and ruminating animals.

Dogs and cats.
Very rare (<1 animal / 10,000 animals
treated, including isolated reports):
Vomiting
, Diarrhoea.
Hypersensitivity reaction (Allergic skin
reactions
), anaphylaxis
1)
Treatment may be discontinued depending on the severity of the undesirable
effects and a benefit/risk evaluation by the veterinary surgeon
2)
In these cases, administration should be discontinued and a symptomatic treatment
given
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or its local representative or the national
competent authority via the national reporting system. See the package leaflet for
respective contact details.

Cross-resistance has been shown between amoxicillin/clavulanic acid and -lactam
antibiotics. Use of the veterinary medicinal product should be carefully considered
when susceptibility testing has shown resistance to lactam antibiotics because its
effectiveness may be reduced.
Methicillin resistant (MRSA) and methicillin resistant S. pseudintermedius
(MRSP) have been isolated in cats and dogs with proportion of resistance that varies
across EU countries.
Do not use in cases of known resistance to the combination of amoxicillin and
clavulanic acid.
Do not use in cases of suspected or confirmed MRSA/MRSP infections, as isolates
should be considered resistant to all including amoxicillin/clavulanic acid
combination.
High resistances (up to 100%) have been reported in isolates from skin and
soft tissue infections in dogs.

Special precautions for safe use in the target species:
In animals with impaired liver and kidney function, the use of the veterinary medicinal
product should be subject to a benefit/risk evaluation by the veterinary surgeon and
the posology evaluated carefully.
Use of the veterinary medicinal product should be based on identification and
susceptibility testing of the target pathogen(s). If this is not possible, therapy should
be based on epidemiological information and knowledge of susceptibility of the target
pathogens at local/regional level.
Use of the veterinary medicinal product should be in accordance with official, national
and regional antimicrobial policies.
Aminopenicillins in combination with beta-lactamase inhibitors are in AMEG category
„C”. An antibiotic with a lower risk of antimicrobial resistance selection (lower AMEG
category) should be used for first line treatment where susceptibility testing suggests
the likely efficacy of this approach.
Narrow spectrum antibiotic therapy with a lower risk of antimicrobial resistance
selection should be used for first line treatment where susceptibility testing suggests
the likely efficacy of this approach.
The tablets are flavoured. In order to avoid any accidental ingestion, store tablets out
of reach of the animals.
The potential for allergic cross-reactivity with other penicillins should be considered.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals:
Penicillins and cephalosporins may cause hypersensitivity (allergy) following
injection, inhalation, ingestion or skin contact. Hypersensitivity to penicillins may lead
to cross reactions to cephalosporins and
substances may occasionally be serious.
Do not handle this veterinary medicinal product if you know you are sensitised, or if
you have been advised not to work with such preparations.
Handle this veterinary medicinal product with great care to avoid exposure, taking all
recommended precautions.
If you develop symptoms following exposure, such as skin rash, you should seek
medical advice and show the doctor this warning.
Swelling of the face, lips or eyes or difficulty breathing are more serious symptoms
and require urgent medical attention.
Wash hands after handling the tablets.
Accidental ingestion of the veterinary medicinal product by a child may be harmful.
To avoid accidental ingestion, particularly by a child, unused part-tablets should be
returned to the open blister space and inserted back into the carton.
In case of accidental ingestion, seek medical advice immediately and show the
package leaflet or the label to the physician.
Special precautions for the protection of the environment:
Not applicable.

The bactericidal activity of amoxicillin may be reduced by the simultaneous use of
bacteriostatic substances such as macrolides, tetracyclines, sulfonamides and
chloramphenicol.
Penicillins may increase the effect of aminoglycosides.

This veterinary medicinal product does not require any special storage conditions.
Return any halved tablet to the opened blister- pack and use within 16h.

Not applicable.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.