Clavaseptin 250 mg Palatable Tablets for Dogs
Active ingredients: Amoxicillin, Clavulanic Acid
Form
Tablet
Species
Manufacturer
Vetoquinol UK Limited
VMD MA No.
08007/5006
What it's used for
In dogs: treatment or adjunctive treatment of periodontal infections caused by bacteria susceptible to amoxicillin in combination with clavulanic acid i.e....
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Prescription required
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Clavaseptin 250 mg Palatable Tablets for Dogs — SPC Details
Source: VMD Summary of Product Characteristics (SPC). Last updated 18 Mar 2026.
susceptible to amoxicillin in combination with clavulanic acid i.e.
Streptococcus spp and Escherichia coli.
To ensure the correct dosage, body weight should be determined as accurately as
possible to avoid under-dosing.
The recommended dose of the product is 10 mg amoxicillin /2.5 mg clavulanic acid per kg
body weight twice a day by the oral route in dogs, i.e. 1 tablet per 20 kg body weight every
12 h, according to the following table:
Bodyweight (kg)Number of tablets twice daily[ 8.1 - 10 ]½[ 10.1- 20 ]1[ 20.1- 30 ]1 ½[ 30.1- 40 ]2
For dogs, in severe periodontal infections the dose may be doubled to 20 mg amoxicillin /
5 mg clavulanic acid/kg body weight twice daily.
Duration of treatment:
- 7 days for the treatment of periodontal infections in dogs.
group or to any of the excipients.
Do not administer to gerbils, guinea pigs, hamsters, rabbits and chinchillas.
Do not administer to horses and ruminating animals.
Do not use in animals with serious dysfunction of the kidneys accompanied by anuria or
oliguria.
Do not use in cases of known resistance to the combination of amoxicillin and clavulanic
acid.
Revised: February 2020
AN: 00191/2019
depending on the severity of the undesirable effects and a benefit/risk evaluation by the
veterinary surgeon.
Hypersensitivity reactions (allergic skin reactions, anaphylaxis) may be observed very
rarely. In these cases, administration should be discontinued and a symptomatic treatment
given.
The frequency of adverse reactions is defined using the following convention:
- very common (more than 1 in 10 animals treated displaying adverse reaction(s))
- common (more than 1 but less than 10 animals in 100 animals treated)
- uncommon (more than 1 but less than 10 animals in 1,000 animals treated)
- rare (more than 1 but less than 10 animals in 10,000 animals treated)
Revised: February 2020
AN: 00191/2019
- very rare (less than 1 animal in 10,000 animals treated, including isolated reports).
Special precautions for use in animals
In animals with impaired liver and kidney function, the use of the product should be subject
to a risk/benefit evaluation by the veterinary surgeon and the posology evaluated carefully.
Caution is advised in the use in small herbivores other than those in 4.3.
Use of the product should be based on susceptibility testing.
Use of the product deviating from the instructions given in the SPC may increase the
prevalence of bacteria resistant to amoxicillin/clavulanic acid and may decrease the
effectiveness of treatment with other antibiotics, due to the potential for cross
resistance. Use of the product should take into account official and local antimicrobial
policies. Do not use in cases of bacteria sensitive to narrow spectrum penicillins or to
amoxicillin as a single substance.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals
Penicillins and cephalosporins may cause hypersensitivity (allergy) following injection,
inhalation, ingestion or skin contact. Hypersensitivity to penicillins may lead to cross
reactions to cephalosporins and . Allergic reactions to these substances may
occasionally be serious.
1. Do not handle this product if you know you are sensitised, or if you have been
advised not to work with such preparations.
2. Handle this product with great care to avoid exposure, taking all recommended
precautions.
3. If you develop symptoms following exposure, such as skin rash, you should seek
medical advice and show the doctor this warning.
Swelling of the face, lips or eyes or difficulty breathing are more serious symptoms and
require urgent medical attention.
Wash hands after handling the tablets.
bacteriostatic substances such as macrolides, tetracyclines, sulfonamides and
chloramphenicol.
The potential for allergic cross-reactivity with other penicillins should be considered.
Penicillins may increase the effect of aminoglycosides.
Revised: February 2020
AN: 00191/2019
5.
This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.
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