Clamoxyl Long Acting 150 mg/ml Suspension for Injection

In common with all other penicillins, amoxicillin should not be used orally or
parenterally in rabbits, guinea pigs, hamsters or gerbils. Caution is advised in its
use in any other very small herbivores. The product is not suitable for
intravenous injection.
Although preruminants such as lambs may be treated orally or parenterally,
animals possessing a functional rumen should only be treated parenterally.
4.4 Special warnings for each target species
Do not use in animals with known sensitivity to the active substance.
The product is not effective against beta-lactamase producing organisms.
Complete cross-resistance has been shown between amoxicillin and other
penicillins, in particular amino-penicillins.
Use of the product/amoxicillin should be carefully considered when antimicrobial
susceptibility testing has shown resistance to penicillins because its
effectiveness may be reduced.
4.5 Special precautions for use
i) Special precautions for use in animals
Shake vial before use. The product does not contain an antimicrobial
preservative. Swab the septum before removing each dose. Since amoxicillin
hydrolyses rapidly in the presence of water, it is important that a dry sterile
needle and syringe is used when withdrawing the suspension to avoid
contaminating the remaining suspension with drops of water.
Do not broach more than 40 times.
Use of the product should be based on susceptibility testing of the bacteria
isolated from the animal. If this is not possible, therapy should be based on
local epidemiological information.

Revised: December 2025
MA split from NI Expiry following AN: 02986/2025
ii) Special precautions to be taken by the person administering the veterinary
medicinal product to animals
Care should be taken to avoid accidental self-injection.
Penicillins and cephalosporins may cause hypersensitivity (allergy) following
injection, inhalation, ingestion or skin contact. Hypersensitivity to penicillins
may lead to cross-reactions to cephalosporins and vice versa. Allergic
reaction to these substances may occasionally be serious.
Do not handle this product if you know you are sensitised, or if you have
been advised not to work with such preparations.
Handle this product with great care to avoid exposure taking all
recommended precautions.
If you develop symptoms following exposure, such as a skin rash, you should
seek medical advice and show the doctor this warning. Swelling of the face,
lips, or eyes or difficulty with breathing are more serious symptoms and
require urgent medical attention.
Wash hands after use.
4.6 Adverse reactions (frequency and seriousness)
Use of the product may occasionally result in local tissue reaction.
Penicillins and cephalosporins may cause hypersensitivity (allergy, allergic skin
reactions) after use. Allergic reactions may occasionally be serious
(anaphylaxis).
The frequency of adverse reactions is defined using the following convention:
- very common (more than 1 in 10 animals treated displaying adverse
reaction(s))
- common (more than 1 but less than 10 animals in 100 animals treated)
- uncommon (more than 1 but less than 10 animals in 1,000 animals treated)
- rare (more than 1 but less than 10 animals in 10,000 animals treated)
- very rare (less than 1 animal in 10,000 animals treated, including isolated
reports).
4.7 Use during pregnancy, lactation or lay
the product is indicated for use in pregnancy and lactation.
4.8 Interaction with other medicinal products and other forms of interaction
It is not generally recommended to use bactericidal and bacteriostatic
antibiotics at the same time.
Beta-lactam antibiotics are known to interact with antibiotics with bacteriostatic
action such as chloramphenicol, macrolides, sulfonamides and tetracyclines.
There is also synergic action of penicillins with aminoglycosides.

Revised: December 2025
MA split from NI Expiry following AN: 02986/2025
4.9 Amounts to be administered and administration route
The product is intended for use via the intramuscular or subcutaneous routes in
cats and dogs and via the intramuscular route only in sheep.
Dosage rate: the recommended dosage rate is 15 mg/kg which is equivalent to
1.0 ml/10 kg bodyweight. The dose may be repeated after 48 hours.
Use a new anatomical site for repeated injections.
To ensure the correct dosage, bodyweight should be determined as accurately
as possible to avoid overdosing.
Dosing guide:
The following table gives examples of doses for the different species.
AnimalSpecimen Weight (kg)Dose (ml)Sheep65