POM-V Prescription Required Companion Animal

Cladaxxa 200 mg/50 mg Chewable Tablets for Cats and Dogs

Active ingredients: Amoxicillin, Clavulanic Acid

Form

Chewable

Species

Cats Dogs

Manufacturer

KRKA, d.d., Novo mesto

VMD MA No.

01656/4201

What it's used for

For the treatment of infections caused by bacteria susceptible to amoxicillin and clavulanic acid including: skin disease (including deep and superficial p...

Full indications, dosage and side effects ↓

View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Amoxicillin + Clavulanic Aci...

1

Ask your vet for a written prescription

They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

Fill it at a registered online retailer

The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Your prescription rights → VMD register of retailers →

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Cladaxxa 200 mg/50 mg Chewable Tablets for Cats and Dogs — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 18 Mar 2026.

For the treatment of infections caused by bacteria susceptible to amoxicillin and
clavulanic acid including: skin disease (including deep and superficial pyodermas);
soft tissue infections (abscesses and anal sacculitis); dental infections (e.g.
gingivitis); urinary tract infections; respiratory disease (involving upper and lower
respiratory tract); enteritis.

Administration: for oral use.
Dosage rate and frequency: 10 mg amoxicillin and 2.5 mg clavulanic acid/kg body
weight (i.e. 12.5 mg of combined active substances per kg bodyweight), twice daily
(corresponding to 25 mg of combined active substances per kg per day).
The following table is intended as a guide to dispensing the product at the
recommended dose rate:
Bodyweight
(kg)
Number of tablets per
dose twice daily
≤8.0Use 40 mg/10 mg
tablet(s)
8.1-10.0½10.1-20.0120.1-30.01 ½

Revised: December 2023
AN: 00798/2023 & 00802/2023Page 4 of 8
30.1-40.02>40.0Use 400 mg/100 mg
tablet(s)
To ensure a correct dosage body weight should be determined as accurately as
possible to avoid underdosing.
If the animal does not accept the tablet from hand or bowl, then the tablets may be
crumbled and added to a little food and fed immediately.
Duration of therapy: The majority of routine cases respond to between 5 and 7 days
therapy. In chronic cases, a longer course of therapy is recommended. In such
circumstances, overall treatment length must be at the clinician’s discretion but
should be long enough to ensure complete resolution of the bacterial disease.

Do not administer to gerbils, guinea pigs, hamsters, rabbits and chinchillas. Do not
use in horses and ruminants.
Do not use in cases of serious dysfunction of the kidneys accompanied by anuria and
oliguria.
Do not use in cases of hypersensitivity to penicillins or other substances of the β-
lactam group or to any excipients.

Revised: December 2023
AN: 00798/2023 & 00802/2023Page 2 of 8
Do not use in cases of known resistance to the combination of amoxicillin and
clavulanic acid.

Very rarely, hypersensitivity reactions to penicillins may occur in treated animals; in
these cases, administration should be discontinued and a symptomatic treatment
given.
Very rarely, gastro-intestinal disturbances (diarrhoea, vomiting, …) may occur after
administration of the product. Treatment may be discontinued depending on the
severity of the undesirable effects and a benefit/risk evaluation by the veterinary
surgeon.
The frequency of adverse reactions is defined using the following convention:
- very common (more than 1 in 10 animals treated displaying adverse reaction(s))
- common (more than 1 but less than 10 animals in 100 animals treated)
- uncommon (more than 1 but less than 10 animals in 1,000 animals treated)
- rare (more than 1 but less than 10 animals in 10,000 animals treated)
- very rare (less than 1 animal in 10,000 animals treated, including isolated reports).

This product is not indicated for cases involving Pseudomonas spp.

Special precautions for use in animals
Whenever possible, the amoxicillin/clavulanic acid combination should only be used
based on susceptibility testing.
Official, national and regional antimicrobial policies should be taken into account
when the product is used.
Use of the product deviating from the instructions given in the SPC may increase the
prevalence of bacteria resistant to amoxicillin/clavulanic acid and may decrease the
effectiveness of treatment with other penicillins, due to the potential for
crossresistance.
A trend in resistance of E. coli.
In animals with hepatic and renal dysfunction, the dosing regimen should be carefully
evaluated and the use of the product based on a risk/benefit evaluation by the
veterinary surgeon.
Caution is advised in the use in small herbivores other than those in section 4.3.
The chewable tablets are flavoured. In order to avoid any accidental ingestion, store
tablets out of reach of the animals.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals
Penicillins and cephalosporins may cause hypersensitivity (allergy) following
inhalation, ingestion or skin contact. Hypersensitivity to penicillins may lead to cross
reactions to cephalosporins and vice versa. Allergic reactions to these substances
may occasionally be serious.
Do not handle this product if you know you are sensitised, or if you have been
advised not to work with such preparations.
Handle this product with care to avoid exposure, taking all recommended
precautions.
If you develop symptoms following exposure such as a skin rash, you should seek
medical advice and show the doctor this warning. Swelling of the face, lips or eyes or
difficulty with breathing, are more serious symptoms and require urgent medical
attention.
Wash hands after use.
To avoid accidental ingestion, particularly by a child, unused part-tablets should be
returned to the open blister space, inserted back into the outer packaging and kept in
a safe place out of the sight and reach of children.

Revised: December 2023
AN: 00798/2023 & 00802/2023Page 3 of 8

Chloramphenicol, macrolides, sulfonamides and tetracyclines may inhibit the
antibacterial effect of penicillins because of the rapid onset of bacteriostatic action.
Penicillins may increase the effect of aminoglycosides.

Do not store above 25 °C.
Store in the original package in order to protect from light and moisture.

Not applicable.
5.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.