POM-V Prescription Required Companion Animal

Chanazine 2% Solution for Injection

Active ingredient: Xylazine

Form

Injection

Species

Cats Cattle Dogs Horses

Manufacturer

Chanelle Pharmaceuticals Manufacturing Ltd

VMD MA No.

08749/5063

What it's used for

Chanazine 2% is a sedative with analgesic and muscle relaxant properties for use in cattle, horses, dogs and cats in cases where sedation is required inclu...

Full indications, dosage and side effects ↓

View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Xylazine

1

Ask your vet for a written prescription

They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

Fill it at a registered online retailer

The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Your prescription rights → VMD register of retailers →

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Chanazine 2% Solution for Injection — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 26 Mar 2026.

Chanazine 2% is a sedative with analgesic and muscle relaxant properties for
use in cattle, horses, dogs and cats in cases where sedation is required
including:
1. Handling fractious animals e.g. for transportation.
2. Medical examinations e.g. X-ray examinations, removal of bandages;
examination of the penis and oral cavity.
3. Premedication for minor superficial operations, and local or regional
anaesthesia.
4. Elimination of defecation when examining and treating the vagina, uterus
and hindquarters.

Cattle:
Chanazine 2% is given by intramuscular injection.
The dose rate is 0.05-0.3 mg/kg (0.25-1.5 ml /100 kg) bodyweight, according to
the degree of sedation required. Very fractious animals may require the higher
dose rates not exceeding 0.3 mg/kg (Dose rate 4).
Dose mg/kg mg/50 kg ml/50 kg
1 0.05 2.5 0.12
2 0.10 5.0 0.25
3 0.20 10 0.50
4 0.30 15 0.75
Horses:
Chanazine 2% is given by slow intravenous injection. Dosage depends upon the
degree of sedation required and the response of the animal and is 0.6-1 mg/kg (3-
5 ml/100 kg) bodyweight. Nervous or excitable horses may require higher doses.
Older horses and those having undergone severe physical exertion before
treatment should receive the lowest dose rate. The horse does not usually
become recumbent with Chanazine 2% and light to deep sedation with variable
degree of analgesia is obtained. Effects are usually seen within 5 minutes and
persist for approximately 20 minutes. Chanazine 2% may be employed in the
horse as a premedication to barbiturate anaesthesia or in combination with
regional or local anaesthesia.
Dogs:
Chanazine 2% is administered intramuscularly at dose rates of 1 - 3 mg/kg (0.05 -
0.15 ml/kg bodyweight). It may be used in combination with a local anaesthetic.
Premedication with atropine may be desirable in some cases. Chanazine 2% is
synergistic with the barbiturates and reduces the dosage of the latter by
approximately one half.
Cats:
Chanazine 2% is administered intramuscularly at a dose rate of 3 mg/kg (0.15
ml/kg bodyweight). Premedication with atropine may occasionally be desirable.

Revised: September 2025
AN: 01687/2025

Not in cases of gastro-intestinal obstruction.
Do not administer by the intra-carotid route.
Careful consideration should also be given before administering to animals
exposed to stress conditions such as extreme heat, cold high altitude or fatigue.

Revised: September 2025
AN: 01687/2025

Following the use of Chanazine 2% in cattle profuse salivation, bloat and polyuria
may occur.
Tympany should be avoided in recumbent cattle by maintaining the animal in
sternal recumbency.
Provision should also be made for facilitating dependent drainage from the mouth
to avoid inhalation asphyxia.
Side effects such as bradycardia, cardiac arrhythmia and polyuria may occur in the
horse.
Following intravenous administration to horses a transient rise followed by a fall in
blood pressure usually occurs.
Vomiting is commonly observed in dogs and cats following use of the product.

Revised: September 2025
AN: 01687/2025

None Known

i. Special precautions for use in animals
Caution where pulmonary disease is suspected.
ii. Special precautions to be taken by the person administering the veterinary
medicinal product to animals
Horses sedated with xylazine usually remain standing and may still kick with
accuracy.
Precaution should be taken to avoid accidental injection / self injection.
1. In the case of accidental oral intake or self-injection, seek medical
advice immediately and show the package leaflet to the doctor but DO
NOT DRIVE as sedation and changes in blood pressure may occur.
2. Avoid skin, eye or mucosal contact.
3. Immediately after exposure, wash the exposed skin with large amounts
of fresh water.
4. Remove contaminated clothes that are in direct contact with the skin.
5. In the case of accidental contactof the product with eyes, rinse with
large amounts of fresh water. If symptoms occur, seek the advice of a
doctor.
6. If pregnant women handle the product, special caution should be
observed not to self-inject as uterine contractions and decreased foetal
blood pressure may occur after accidental systemic exposure.
7. Advice to Doctors: Xylazine is an alpha2-adrenoreceptor agonist.
Symptoms after absorption may involve clinical effects including dose-
dependent sedation, respiratory depression, brachycardia, hypotension,
a dry mouth, and hyperglycaemia. Ventricular arrhythmias have also
been reported. Respiratory and haemodynamic symptoms should be
treated symptomatically.

Do not store above 25°C.
Following withdrawal of the first dose, use the product within 28 days.
Discard unused material.

large amounts of fresh water. If symptoms occur, seek the advice of a
doctor.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.