POM-V Prescription Required

Chanazine 10% Solution for Injection

Active ingredient: Xylazine

Form

Injection

Species

Horses

Manufacturer

Chanelle Pharmaceuticals Manufacturing Ltd

VMD MA No.

08749/5180

What it's used for

Xylazine is a sedative with analgesic and muscle relaxant properties. The product is for use in horses only, in cases where sedation is required including:...

Full indications, dosage and side effects ↓

View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Xylazine

1

Ask your vet for a written prescription

They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

Fill it at a registered online retailer

The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Your prescription rights → VMD register of retailers →

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Chanazine 10% Solution for Injection — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 26 Mar 2026.

Xylazine is a sedative with analgesic and muscle relaxant properties. The
product is for use in horses only, in cases where sedation is required including:
1. Handling fractious animals e.g. for transportation.
2. Medical examinations e.g. X-ray examinations, removal of bandages;
examination of the penis and oral cavity.
3. Premedication for minor superficial operations, and local or regional
anaesthesia.
4. Elimination of defaecation when examining and treating the vagina,
uterus and hindquarters.

The product is given by slow intravenous injection. Dosage depends on the
degree of sedation required and the response of the animal, and is 0.5 – 1
ml/100 kg (0.5 - 1 mg/ kg bodyweight). Nervous or excitable horses may
require higher doses. Older horses and those having undergone severe
physical exertion before treatment should receive the lowest dose rate.

Animals do not usually become recumbent after administration and light to deep
sedation with variable degree of analgesia is obtained. Effects are usually seen
within 5 minutes and persist for approximately 20 minutes. The product may be
employed as a premedication to barbiturate anaesthesia or in combination with
regional or local anaesthesia.

Do not administer by the intra-carotid route.
Careful consideration should be given before administering to animals exposed
to stress conditions such as extreme heat, cold, high altitude or fatigue.

Side effects of bradycardia, cardiac arrhythmia and polyuria may occur.
Following intravenous administration a transient rise followed by a fall in blood
pressure usually occurs.

None known

Amended pages: November 2025
AN: 01686/2025

i. Special precautions for use in animals
Should be used with caution when pulmonary disease is suspected.
Do not exceed the recommended dosage
ii. Special precautions to be taken by the person administering the veterinary
medicinal product to animals
Horses sedated with xylazine usually remain standing and may still kick
with accuracy.
Precaution should be taken to avoid accidental injection / self-injection.
1. In the case of accidental oral intake or self-injection, seek medical
advice immediately and show the package leaflet to the doctor but
DO NOT DRIVE as sedation and changes in blood pressure may
occur.
2. Avoid skin, eye or mucosal contact.
3. Immediately after exposure, wash the exposed skin with large
amounts of fresh water.
4. Remove contaminated clothes that are in direct contact with skin.
5. In the case of accidental contact of the product with eyes, rinse with
large amounts of fresh water. If symptoms occur, seek the advice of
a doctor.
6. If pregnant women handle the product, special caution should be
observed not to self inject as uterine contractions and decreased
foetal blood pressure may occur after accidental systemic
exposure.
7. Advice to Doctors: Xylazine is an alpha2-adrenoreceptor agonist.
Symptoms after absorption may involve clinical effects including
dose-dependent sedation, respiratory depression, brachycardia,
hypotension, a dry mouth, and hyperglycaemia. Ventricular
arrhythmias have also been reported. Respiratory and
haemodynamic symptoms should be treated symptomatically.

None known.

large amounts of fresh water. If symptoms occur, seek the advice of
a doctor.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.