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POM-V Prescription Required

Cevac Mass L Lyophilisate for Oculonasal Suspension

Active ingredient: Infectious bronchitis virus

Form

Solution

Species

Chickens

Manufacturer

Ceva Sante Animale

VMD MA No.

14966/5002

What it's used for

For the active immunisation of broilers and future layers against infectious bronchitis (Massachusetts serotype), in order to reduce respiratory clinical s...

Full indications, dosage and side effects ↓
View official SPC (PDF)

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Prescription required

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Clinical information

Cevac Mass L Lyophilisate for Oculonasal Suspension — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 26 Mar 2026.

For the active immunisation of broilers and future layers against infectious bronchitis
(Massachusetts serotype), in order to reduce respiratory clinical signs, detrimental
effect on the ciliary activity and presence of virus in the trachea.
Protection was demonstrated by challenge with the Massachusetts M41 strain.
Onset of immunity: 3 weeks following vaccination.
Duration of immunity: 9 weeks following vaccination.
For nebulisation use.
The vaccine should be administered from one day of age, one dose / chicken.
Reconstitute the vaccine in distilled water, or in cold, clear water, free from
disinfectants. The quantity of water should be sufficient to allow a uniform distribution
of the vaccine when spraying the chickens. The content of a 1000-dose vaccine vial is
recommended to be dissolved in 200 ml water, whereas this ratio should be
considered when dissolving other types of presentation.
The vaccine should be applied as coarse spray with a droplet size of 100-200 µm. It is
preferable that the chickens are sitting together in dim light or closely confined during
spraying. The ventilation should be switched off during and after vaccination in order to
avoid turbulences. Vaccination should be performed during the coolest time of the day.
None.
No significant clinical symptoms were detected after administration of the product. Mild
tracheal rales commonly occurred in animals 4-6 days after vaccination, which
resolved completely in a few days. In rare cases transient conjunctivitis can occur.
The frequency of adverse reactions is defined using the following convention:
- very common (more than 1 in 10 animals treated displaying adverse reaction(s))
- common (more than 1 but less than 10 animals in 100 animals treated)
- uncommon (more than 1 but less than 10 animals in 1,000 animals treated)
- rare (more than 1 but less than 10 animals in 10,000 animals treated)
- very rare (less than 1 animal in 10,000 animals treated, including isolated reports)
Vaccinate healthy animals only.

Revised: August 2025
AN: 01269/2025 and AN: 01600/2025Page 2 of 5

Special precautions for use in animals
Vaccinated chickens may excrete the vaccine strain for up to 28 days following
vaccination.
During this time, special precautions should be taken to avoid spreading of the vaccine
strain to unvaccinated chickens and to other bird species, if any are close by.
All chickens within the same farm should be vaccinated before or when entering the
premises.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals
Care should be taken when reconstituting and administering the vaccine. Wash and
disinfect hands and equipment after administration of the vaccine. When spraying the
vaccine, personal protective equipment consisting of a mask with eye protection
should be worn by the operator and staff.
Safety and efficacy data are available which demonstrate that this vaccine can be
mixed and administered with Cevac IBird by spray application in chickens from day old
onwards. Do not use the mixed products in birds in lay and within 4 weeks before the
onset start of the laying period. The mixed products protect against strains belonging
to Massachusetts and 793/B groups of IBV. The safety parameters of the mixed
vaccines are not different from those described for the vaccines administered
separately. Read the product information of Cevac IBird before use.
Care should be taken to avoid spreading of the vaccine strains to other bird species, in
particular when the vaccines are mixed.
Simultaneous use of both vaccines may increase the risk of recombination of viruses
and potential emergence of new variants. However, the chance of a hazard occurring
has been estimated very low.

Revised: August 2025
AN: 01269/2025 and AN: 01600/2025Page 3 of 5
No information is available on the safety and efficacy of this vaccine when used with
any other veterinary medicinal product except Cevac IBird. A decision to use this
vaccine before or after any other veterinary medicinal product therefore needs to be
made on a case by case basis.
Store and transport refrigerated (2 °C - 8 °C).
Protect from light.
The reconstituted vaccine is to be kept below 25°C.
Zero days.
5. IMMUNOLOGICAL PROPERTIES
Pharmacotherapeutic group: immunologicals for aves / domestic fowl / live viral
vaccines / avian infectious bronchitis virus
ATCvet code: QI01AD07
To stimulate active immunity against the Massachusetts serotype of avian infectious
bronchitis virus in chickens.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.

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