POM-V Prescription Required

Cevac Chlamydia

Active ingredient: Chlamydophila abortus

Form

Injection

Species

Sheep

Manufacturer

Ceva Sante Animale

VMD MA No.

14966/5014

What it's used for

For the active immunisation of susceptible breeding female sheep to reduce abortion caused by infection.

Full indications, dosage and side effects ↓

View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Chlamydophila abortus

1

Ask your vet for a written prescription

They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

Fill it at a registered online retailer

The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Your prescription rights → VMD register of retailers →

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Cevac Chlamydia — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 26 Mar 2026.

For the active immunisation of susceptible breeding female sheep to reduce abortion
caused by infection.

The vaccine is supplied in vials containing 10, 20, 50 or 100 doses.
Reconstitution: The vaccine is reconstituted with the solvent immediately prior to
use, allowing
2 ml of diluent per dose. If using the vented transfer device push one end of the
device through the centre of the vaccine vial using a firm, twisting action. Similarly,
push the solvent vial onto the opposite end of the device taking care to ensure the
spike penetrates the centre of the vial bung. Carefully allow diluent to flow into the
vaccine vial without completely filling it. Ensure the powder plug is fully dissolved and
then invert until all the vaccine solution drains into the diluent vial. Remove the empty
vaccine vial and transfer spike from the diluent vial and place into an appropriate
disinfectant solution. Alternatively, remove approximately 5 ml of the solvent from the
vial with a syringe and needle, inject into the vaccine vial and shake well until the
powder plug is fully dissolved. Remove the vaccine solution from the vial, reinject into
the diluent vial and shake well. Great care should be taken not to generate an
aerosol.
Administration Dose: 2 ml by intramuscular or subcutaneous injection. Ewe lambs,
where it is intended to breed from them, may be vaccinated from 5 months of age.
Shearlings and older ewes should be vaccinated during the 4 month period prior to
mating.
Injection equipment To minimise the risk of self-injection the vaccine should be
administered using automatic syringes fitted with the sterimatic guarded needle
system according to the manufacturer's instructions. It is vital that a vented draw off
tube is used with this equipment. Regular checks should be made to ensure the
syringes are properly calibrated. Carefully attach the vial of reconstituted vaccine to
the injection equipment and avoid aerosols during the priming process. It may be
advisable to wear a visor while carrying out this operation.

Do not vaccinate animals less than 4 weeks before mating. Do not vaccinate
pregnant animals Do not vaccinate animals which are being treated with
antimicrobials, particularly tetracyclines.

A transient temperature rise may be observed after vaccination (average of 1.5°C for
a maximum of 3 days).
Molecular investigations revealed the possible presence of the vaccine strain 1B in
placentas collected in cases of enzootic abortion of ewes vaccinated with Cevac
Chlamydophila. Although the causal relationship has not been firmly established
(differential diagnosis incomplete), and the representative sampling should be
specified in the domestic context, the possibility that the vaccine strain can be at the
origin of abortions can not however be excluded in the present state of knowledge.
This should be considered in the benefit / risk analysis conducted by the vet before
prescribing the vaccine, especially in farms where the infection pressure related to
Chlamydophila abortus is low.In very rare cases the vaccine may cause
hypersensitivity reactions.

Chlamydophila abortus is only one of the causes of abortion in sheep. If abortion
rates remain unchanged in flocks which have been vaccinated with Cevac
®
Chlamydia it is recommended that veterinary advice is sought. The epidemiology of
abortion due to Chlamydophila abortus in ewes involves a long incubation period.
Ewes that abort in any lambing season have usually been infected at the previous
lambing. Field trial data indicate that vaccinating incubating ewes will reduce the
incidence of abortion, but a proportion can still go on to abort. Care should be taken
in handling such abortions as susceptible humans may be at risk of infection.

Revised: September 2025
AN: 01751/2025

the person administering the medicinal product to animals
i. Special precautions for use in animals
Not applicable.
ii. Special precautions to be taken by the person administering the medicinal
product to animals
Cevac® Chlamydia should not be handled by pregnant women or women of child
bearing age as the vaccine may cause abortion. Cevac® Chlamydia should not be
handled be persons who are immune-deficient (e.g. AIDS sufferers, persons
undergoing chemotherapy or taking immune-suppressive drugs.) If in any doubt, you
should consult your GP. Operators should wear gloves when handling the vaccine.
Care should be taken to avoid self-injection, but if this occurs, immediate medical
advice should be sought and the doctor informed that self injection with a living
Chlamydophila vaccine has occurred. Tetracycline therapy is the current recognised
treatment for infection with Chlamydophila abortus in humans.

Safety and efficacy data are available which demonstrate that this vaccine can be
administered the same day but not mixed with a commercial
vaccine containing live tachyzoites of the S48 strain. No information is available on
the safety and efficacy of this vaccine when used with any other veterinary medicinal
product except the products mentioned above. A decision to use this vaccine before

Revised: September 2025
AN: 01751/2025
or after any other veterinary medicinal product therefore needs to be made on a case
by case basis.

Store between +2° and +8°C. Protect from light. Do not freeze.

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This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.